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| 1 | Massive haemorrhage in liver transplantation:Consequences,prediction and management显示文摘From its inception the success of liver transplantation has been associated with massive blood loss. Massive transfusion is classically defined as > 10 units of red blood cells within 24 h, but describing transfusion rates over a shorter period of time may reduce the potential for survival bias. Both massive haemorrhage and transfusion are associated with increased risk of mortality and morbidity(need for dialysis/surgical site infection) following liver transplantation although causality is difficult to prove due to the observational design of most trials. The blood loss associated with liver transplantation is multifactorial. Portal hypertension secondary to cirrhosis results in extensive collateral circulation, which can bleed during hepatectomy particular if portal pressures are increased. Avoiding volume loading and maintenance of a low central venous pressure together with the use of vasopressors have been shown to reduce blood loss and transfusion during liver transplantation, but may increase the risk of renal impairment post-operatively. Coagulation defects may be present pre-transplant, but haemostasis is often re-balanced due to a deficit in both proand anti-coagulation factors. Further derangement of haemostasis may develop in the anhepatic and neohepatic phases due to absent hepatic metabolic function, hyperfibrinolysis and platelet sequestration in the donor liver. Point-of-care tests of coagulation such as the viscoelastic tests rotation thromboelastometry/thromboelastometry allow and more accurate and rapid assessment of these derangements in coagulation and guide the use of factor replacement and antifibrinolytics. Transfusion protocols guided by these tests have been shown to reduce transfusion rates compared with conventional coagulation tests, but have not shownimprovements in mortality or morbidity. Pre-operative factors associated with massive transfusion include previous surgery, re-do transplantation, the aetiology and severity of liver disease. Intra-operatively the use of piggy-back technique and avoiding veno-veno bypass has been shown to reduced blood loss. | Stuart Cleland Carlos Corredor Jia Jia Ye Coimbatore Srinivas Stuart A Mc Cluskey | 2016 | World Journal of Transplantation2016，6，2： | 11 |
| 2 | Detection and quantitation of fowl adenovirus genome by a real-time PCR assay显示文摘 | Nadya Romanova Juan Carlos Corredor éva Nagy | 2009 | Journal of Virological Methods2009，，1： | 1 |
| 3 | Gastrointestinal polyps in children:advances in molecular genetics,diagnosis,and management显示文摘 | CORREDOR J WAMBACH J BARNARD J | 2001 | J Pediatr2001，138，5： | 1 |
| 4 | Structural styles in the deep-water fold and thrust belts of the Niger Delta显示文摘 | Corredor F Shaw J H Bilotti F | | 0，，06： | 1 |
| 5 | Endogenous fungal endophthalmitis:risk factors,clinical course,and visual outcome in 13 patients显示文摘AIM:To analyze the risk factors,ophthalmological features,treatment modalities and their effect on the visual outcome in patients with endogenous fungal endophthalmitis(EFE).METHODS:Data retrieved from the medical files included age at presentation to the uveitis clinic,gender,ocular symptoms and their duration before presentation,history of fever,eye affected,anatomical diagnosis and laboratory evidence of fungal infection.Medical therapy recorded included systemic antifungal therapy and its duration,use of intravitreal antifungal agents and use of oral/intravitreal steroids.Surgical procedures and the data of ophthalmologic examination at presentation and at last follow-up were also collected.RESULTS:Included were 13 patients(20 eyes,mean age 58 y).Ten patients presented after gastrointestinal or urological interventions and two presented after organ transplantation.In one patient,there was no history of previous intervention.Diagnostic vitrectomy was performed in 16 eyes(80%)and vitreous cultures were positive in 10 of the vitrectomized eyes(62.5%).In only 4 patients(31%),blood cultures were positive.All patients received systemic antifungal therapy.Sixteen eyes(80%)received intravitreal antifungal agent with voriconazole being the most commonly used.Visual acuity(VA)improved from 0.9±0.9 at initial exam to 0.5±0.8 logMAR at last followup(P=0.03).A trend of greater visual improvement was noted in favor of eyes treated with oral steroids(±intravitreal dexamethasone)than eyes that were not treated with steroids.The most common complication was maculopathy.Twelve eyes(60%)showed no ocular complications.CONCLUSION:High index of suspicion in patients with inciting risk factors is essential because of the low yield of blood cultures and the good general condition of patients at presentation.Visual prognosis is improved with the prompt institution of systemic and intravitreal pharmacotherapy and the immediate surgical intervention.Oral±local steroids could be considered in cases of prolonged or marked inflammatory responses in order to hasten control of inflammation and limit ocular complications. | Jamel Corredores Itzhak Hemo Tareq Jaouni Zohar Habot-Wilner Michal Kramer Shiri Shulman Haneen Jabaly-Habib Ala'a Al-Talbishi Michael Halpert Edward Averbukh Jaime Levy Iris Deitch-Harel Radgonde Amer | 2021 | International Journal of Ophthalmology(English edition)2021，14，1： | 1 |
| 6 | Performance and characterization of dispersion strengthened Cu-TiB2 composite for electrical use 显示文摘 | LOPEZ M CORREDOR D CAMURRI C VERGARA V JIMENEZ J | 2005 | Materials Characterization2005，55，45： | 1 |
| 7 | Structral styles in the deep water fold and thrust belts of the Niger Delta显示文摘 | Corredor F Shaw J h Bilotti F | | 0，，06： | 1 |
| 8 | Diastolic dysfunction and mortality in septic patients: a systematic review and meta- analysis显示文摘 | Sanfilippo F Corredor C Fletcher N | 2015 | Intensive Care Med2015，32，6： | 1 |
| 9 | Persistence of spilled oil in a tropical intertidal environment 显示文摘 | Corredor J E J M Morrell Castillo C E D | 1990 | Mar Pollut Bull1990，21，8： | 1 |
| 10 | Tumor necrosis factor regulates intestinal epithelial cell migration by receptor-dependent mechanisms显示文摘 | CORREDOR J YAN F SHEN CC | 2003 | Am J Physiol Cell Physiol2003，284，4： | 1 |
| 11 | Factors affecting prognosis in childhood Guillain Barre Syndrone 显示文摘 | Ortiz corredor F | 2004 | Rev Neurol2004，38，6： | 1 |
| 12 | Structural styles in the deep-water fold and thrust belts of Niger Delta 显示文摘 | Corredor F John H Shaw | 2005 | AAPG Bulletin2005，89，6： | 1 |
| 13 | β1 Integrin fo- cal adhesion kinase (FAK) signaling modulates retinal ganglion eell(RGC) survival显示文摘 | Santos AR Corredor RG Obeso BA | 2012 | PLoS One2012，7，48： | 1 |
| 14 | El efecto dia de la semana: Resuhados Sobre Algunos Mereados de Valores Europeos 显示文摘 | Corredor P R Santamarfa | 1996 | Revista Espanola de Financiacion y Contabilidad1996，25，86： | 1 |
| 15 | Transition metal-coated nanoparticle films: vibrational characterization with surface-enhanced Raman scattering 显示文摘 | Park S Yang P Corredor P | 2002 | J Am Chem Soc2002，124，： | 1 |
| 16 | Increase of nitrous oxide flux to the atmosphere upon nitrogen addition to red mangroves sediments显示文摘 | Mufioz-Hincapi~ M Morell J M Corredor J E | 2002 | Marine Pollution Bulletin2002，44，10： | 1 |
| 17 | Natural evolution of carpal tunnel syndrome in untreated patients显示文摘 | Ortiz -Corredor F Enriquez F Diaz-Ruiz J et d | 2008 | Clin Neurophysiol2008，119，6： | 1 |
| 18 | Three-dimensional geometry and kine matics of the west ern thrust front of the eastern Cordillera显示文摘 | Corredor F O | 1996 | Columbia AAPGS EPM1996，，5： | 1 |
| 19 | Nitrogen cycling and anthropogenic impact in the tropical interamerican seas显示文摘 | Jorge E. Corredor Robert W. Howarth Robert R. Twilley Julio M. Morell | 1999 | Biogeochemistry (-)1999，，1： | 1 |
| 20 | One- and two-photon photochromism of 3,4-bis- ( 2,4, 5-trimethyl-thiophen-3-yl) furan-2, 5- dione显示文摘 | Corredor C C Belfield K D Bondar M V | 2006 | J Photoehem Photobiol A: Chem2006，184，： | 1 |
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