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| 1 | 与久坐者相比,职业运动员的肠道菌群在代谢组分,尤其是功能代谢水平上有所不同显示文摘目的有证据表明肠道菌群以及影响其结构和活性的因素在人类代谢、免疫和发育过程中发挥作用。我们曾报道,与久坐者相比,诸如职业运动员,配有相应饮食的极度体育活动者肠道菌群种属和代谢组分发生了改变。这次我们重点研究这些因素对菌群功能/代谢活动的影响,以进一步揭示运动者和久坐者间的差别。方法对专业国际橄榄球联盟球员(样本数为40例)和对照(样本数为46例)的肠道菌群进行代谢表型和功能宏基因组分析,并将结果与生活方式指标(比如饮食习惯)和临床评估指标(比如血清肌酸激酶)进行关联。结果与对照相比,运动员组中与肌肉更新和整体健康相关的信号通路(比如:氨基酸、抗生素生物合成和碳水化合物代谢)和肠道菌群代谢产物(比如:短链脂肪酸乙酸酯、丙酸酯和丁酸酯)有所增加。结论运动和久坐相比,其肠道菌群在宏基因组和代谢组学上比组织水平显示出更大差异,拓展了饮食.运动.肠道微生态模式新视野。 | Barton W Penney NC Cronin O Garcia-Perez I Molloy MG Holmes E Shanahan F Cotter PD O'Sullivan O 毛玲娜 宋震亚 | 2017 | 英国医学杂志中文版2017，20，7： | 2 |
| 2 | Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models显示文摘 | Murphy EF Cotter PD Healy S | 2010 | Gut2010，59，12： | 1 |
| 3 | Prenatal diagnosis of a fetus with two balanced de nov{} chromosome rearrangements显示文摘 | Cotter PD Caggana M Willner JP | 1996 | Am J Med Genet1996，66，2： | 1 |
| 4 | Genomic rearrangements of PTEN in prostate cancer显示文摘 | Phin S Moore MW Cotter PD | 2013 | Front Oncol2013，3，： | 1 |
| 5 | Transformation of follicular lymphoma to Burkitt-like lymphoma within a single lymph node显示文摘 | Mukhopadhyay S Readling J Cotter PD | 2005 | Hum Pathol2005，36，3： | 1 |
| 6 | Bacteriocins:biological tools for bio-preservation and shelf-life extension显示文摘 | Deegan LH Cotter PD Hill C | 2006 | International Dairy Journal2006，16，9： | 1 |
| 7 | Bacteriocins: Biological tools for bio-preservation and shelf-life extension 显示文摘 | Deegan LH Cotter PD Hill C | 2006 | Int Dairy J2006，16，9： | 1 |
| 8 | Strategies to improve the bacteriocin protection provided by lactic acid bacteria显示文摘 | O’Shea EF Cotter PD Ross RP | 2013 | Current Opinion in Biotechnology2013，24，2： | 1 |
| 9 | Composition and energy harvesting capacity of the gut microbiota:relationship to diet,obesity and time in mouse models显示文摘 | Murphy EF Cotter PD Healy S | | 0，，： | 1 |
| 10 | Surviving the acid test: Responses of grampositive bacteria to low pH显示文摘 | Cotter PD Hill C | 2003 | Microbiol Mol Biol Rev2003，67，3： | 1 |
| 11 | Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models 显示文摘 | Murphy EF Cotter PD Healy S | 2010 | Gut2010，59，： | 1 |
| 12 | Prenatal diagnosis of afetus with two balanced de novo chromosome rearrangements 显示文摘 | Cotter PD Caggana M Willner JP | 1996 | Am J Med Genet1996，66，： | 1 |
| 13 | Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in diet-induced obesity 显示文摘 | Murphy EF Cotter PD Hogan A O'Sullivan O Joyce A Fouhy F Clarke SF Marques TM O'Toole PW Stanton C Quigley EM Daly C Ross PR OtDoherty RM Shanahan F | 2013 | Gut2013，62，2： | 1 |
| 14 | Rapid prenatal diagnosis in transloeation carriers by interphase FISH with chromosome-spe- cific subtelomere probes显示文摘 | Cotter PD Musci TJ Norton ME | 2003 | Am J Med Genet A2003，122，1： | 1 |
| 15 | Enzymatic defect in 'X-linked' sideroblastic anemia:molecular evidence for erythroid delta-aminolevulinate synthase deficiency显示文摘 | Cotter PD Baumann M Bishop DF | | 0，，： | 1 |
| 16 | Bacteriocins: developing innate im- munity for food 显示文摘 | Cotter PD Hill C Ross RP | 2005 | Nat Rev Microbiol2005，3，10： | 1 |
| 17 | Composition and energy harvesting capacity of the gut microbiota= relationship to diet,obe sity and time in mouse models显示文摘 | Murphy EF Cotter PD Healy S | 2010 | Gut2010，59，12： | 1 |
| 18 | Prenatal diagnosis of afetus with two balanced de novo chromosome rearrangementa显示文摘 | Cotter PD Caggana M Willner JP | 1996 | Am J Med Genet1996，66，： | 1 |
| 19 | Listeriolysin S, a Novel Peptide Haemolysin Associated with a Subset of Lineage I Listeria monocytogenes 显示文摘 | Cotter PD Draper LA Lawton EM | 2008 | PLoS Pathog2008，4，10： | 1 |
| 20 | Interphase FISH with chromosome specific protelomere probes for rapiod prenatal diagnosis in a reciprocal translocation carrier显示文摘 | Cotter PD Musci JJ | 2001 | Prenat Diagn2001，21，3： | 1 |
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