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| 1 | Acute antibody-mediated rejection after intestinal transplantation显示文摘AIM To investigate the incidence, risk factors and clinical outcomes of acute antibody-mediated rejection(ABMR) after intestinal transplantation(ITx).METHODS A retrospective single-center analysis was performed to identify cases of acute ABMR after ITx, based on the presence of donor-specific antibody(DSA), acute tissue damage, C4 d deposition, and allograft dysfunction.RESULTS Acute ABMR was identified in 18(10.3%) out of 175 intestinal allografts with an average occurrence of 10 d(range, 4-162) after ITx. All acute ABMR cases were presensitized to donor human leukocyte antigens class Ⅰand/or Ⅱ antigens with a detectable DSA. A positive cross-match was seen in 14(77.8%) cases and twelve of 18 patients(66.7%) produced newly-formed DSA following ITx. Histological characteristics of acute ABMR include endothelial C4 d deposits, interstitial hemorrhage, and severe congestion with focal fibrin thrombin in the lamina propria capillaries. Multivariate analysis identified a liver-free graft and high level of panel reactive antibodyas a significant independent risk factor. Despite initial improvement after therapy, eleven recipients(61.1%) lost transplant secondary to rejection. Of those, 9(50%) underwent graft removal and 4(22.2%) received second transplantation following acute ABMR. At an average follow-up of 32.3 mo(range, 13.3-76.4), 8(44.4%) recipients died.CONCLUSION Our results indicate that acute ABMR is an important cause of intestine graft dysfunction, particularly in a liver-exclusive graft and survivors are at an increased risk of developing refractory acute rejection and chronic rejection. More effective strategies to prevent and manage acute ABMR are needed to improve outcomes. | Guo-Sheng Wu Ruy J Cruz Jr Jun-Chao Cai | 2016 | World Journal of Transplantation2016，6，4： | 5 |
| 2 | Chitosan microparticles as injectable scaffolds for tissue engineering 显示文摘 | CRUZ D M IVIRICO J L GOMES M M | 2008 | J Tissue Eng Regen Med2008，2，6： | 1 |
| 3 | Supply chain networks, electronic commerce, and supply side and demand side risk显示文摘 | NAGURNEY A CRUZ J DONG J | 2005 | European Journal of Operational Research2005，164，： | 1 |
| 4 | Studies on the extraction and composition of rice protein显示文摘 | Cruz L J Espiritu S G | 1966 | Cereal Chem1966，43，： | 1 |
| 5 | Purification of metallurgical grade silicon by acid leaching显示文摘 | SANTOS I C GONCALVES A P SANTOS C S ALMEIDA M AFONSO M H CRUZ M J | 1990 | Hydrometallurgy1990，23，： | 1 |
| 6 | Allergic rhinitis and its im- pact on asthma (ARIA)2008 update (in collaboration with the World Health Organization,GA(2)LEN and AllerGen)显示文摘 | Bousquet J Khaltaev N Cruz AA | 2008 | Allergy2008，，： | 1 |
| 7 | Biomechanical comparison of unipedicular versus bipedicular kyphoplasty显示文摘 | Steinmann J Tingey CT Cruz G | 2005 | Spine2005，30，2： | 1 |
| 8 | Study of the migration of benzophenone from printed paperboard packages to cakes through different plastic films 显示文摘 | Pastorelli S Sanches-Silva A Cruz J M | 2008 | Eur Food Res Technol2008，227，： | 1 |
| 9 | Amphotericin B therapy: past, present, and future 显示文摘 | Peacock J E Herrington D A Cruz J M | 1993 | Infect Dis Clin Pract1993，2，： | 1 |
| 10 | A Nonlinear Discriminant Algorithm for Feature Extraction and Data Classification显示文摘 | Cruz C S Dorronsoro J R | 1998 | IEEE Transactions on Neural Networks1998，9，6： | 1 |
| 11 | Xylitol Production from Wood Hydrolyzaties by Entrapped Debammyas Hansenii and Candida Guilliermondi Cells显示文摘 | Dominguez J M Cruz J M Roca E | | 0，，： | 1 |
| 12 | Aneurysmal ('angiomatoid') fibrous histioeytoma of the skin 显示文摘 | Santa Cruz D J Kyriakos M | 1981 | Cancer1981，47，8： | 1 |
| 13 | Surgical and visual outcomes of the type I Boston Kera- toprosthesis for the management of aniridic fibrosis syndrome in congenital aniridia 显示文摘 | Bakhtiari P Chan C Welder JD de la Cruz J Holland E J Djalil- ian AR | 2012 | Am J Ophthalmol2012，153，5： | 1 |
| 14 | Effects of salbutamol on ex- haled breath condensate biomarkers in acute lung injury:prospective analysis显示文摘 | Roca O G6mez-Oll6s S Cruz M J | 2008 | Crit Care2008，12，3： | 1 |
| 15 | Distinct roles of isoforms of the heme-liganded nuclear receptor E75, an insect ortholog of the vertebrate Rev-erb, in mosquito reproduction 显示文摘 | Cruz J Mane-Padros D Zou Z | 2012 | Molecular and Cellular Endocrinology2012，349，2： | 1 |
| 16 | Update on peripartum cardiomyopa- thy 显示文摘 | Cruz MO Briller J Hibbard JU | 2010 | Obstetrics and gynecology clinics of North America2010，37，2： | 1 |
| 17 | Hypothermic reperfusion after cardiac arrest augments brain-derived neurotrophic factor ac- tivation显示文摘 | D' Cruz B J Fertig KC Filiano AJ | 2002 | J Cereb Blood Flow Metab2002，22，7： | 1 |
| 18 | Nuclear receptor BgFTZ-F1 regulates molting and the timing of ecdysteroid production during nymphal development in the hemimetabolous insect Blattella germanica显示文摘 | Cruz J Nieva C Mané-Padrós D | | 0，，11： | 1 |
| 19 | Stabilization and non- linear control for a novel trirotor mini -aircraft显示文摘 | Salazar - Cruz S Lozano R Esearefio J | 2009 | Control En- gineering Practice2009，17，8： | 1 |
| 20 | Fine-tuning of the piping model through small-scale,medium-scale and ijkdijk experiments 显示文摘 | SELLMEIJER J B LOPEZ de LA CRUZ J van BEEK V M KNOEFF J G | 2011 | European Journal of Environmental and Civil Engineering2011，15，8： | 1 |
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