|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Yes相关蛋白通过肿瘤坏死因子受体相关因子6控制内皮活化和血管炎症显示文摘继发于异常的内皮激活的微血管炎症和内皮功能障碍在败血症和器官衰竭的病理生理学中起关键作用。抑制内皮细胞过度活化的内在信号传导机制尚未完全明了。该研究旨在确定Yes相关蛋白(Yes-associated protein,YAP)(Hippo通路的主要转录共激活剂)在调节内皮活化和血管炎症的强度和程度中的中心作用。 | 刘青 叶鹏 Lv Y Kim K Sheng Y Cho J Qain Z Zhao YY Hu G Pan D Malik AB | 2018 | 中华高血压杂志2018，26，8： | 20 |
| 2 | Genome resequencing and transcriptome profiling reveal structural diversity and expression patterns of constitutive disease resistance genes in Huanglongbing-tolerant Poncirus trifoliata and its hybrids显示文摘Huanglongbing(HLB)is the most destructive bacterial disease of citrus worldwide.While most citrus varieties are susceptible to HLB,Poncirus trifoliata,a close relative of Citrus,and some of its hybrids with Citrus are tolerant to HLB.No specific HLB tolerance genes have been identified in P.trifoliata but recent studies have shown that constitutive disease resistance(CDR)genes were expressed at much higher levels in HLB-tolerant Poncirus hybrids and the expression of CDR genes was modulated by Candidatus Liberibacter asiaticus(CLas),the pathogen of HLB.The current study was undertaken to mine and characterize the CDR gene family in Citrus and Poncirus and to understand its association with HLB tolerance in Poncirus.We identified 17 CDR genes in two citrus genomes,deduced their structures,and investigated their phylogenetic relationships.We revealed that the expansion of the CDR family in Citrus seems to be due to segmental and tandem duplication events.Through genome resequencing and transcriptome sequencing,we identified eight CDR genes in the Poncirus genome(PtCDR1-PtCDR8).The number of SNPs was the highest in PtCDR2 and the lowest in PtCDR7.Most of the deletion and insertion events were observed in the UTR regions of Citrus and Poncirus CDR genes.PtCDR2 and PtCDR8 were in abundance in the leaf transcriptomes of two HLB-tolerant Poncirus genotypes and were also upregulated in HLB-tolerant,Poncirus hybrids as revealed by real-time PCR analysis.These two CDR genes seem to be good candidate genes for future studies of their role in citrus-CLas interactions. | Nidhi Rawat Brajendra Kumar Ute Albrecht Dongliang Du Ming Huang Qibin Yu Yi Zhang Yong-Ping Duan Kim D Bowman Fred G Gmitter Jr Zhanao Deng | 2017 | Horticulture Research2017，4，1： | 5 |
| 3 | Nat Genet:单基因突变导致过敏性皮炎的发生显示文摘最近,研究者们鉴定出了一类导致神经性皮炎发生的关键基因突变:CARDll。来自美国NIH过敏与传染病研究所的研究者们通过对四个没有血缘关系的患病家庭进行分析,发现了这一导致疾病产生的基因、 | Chi A Ma, Yuan Zhang, Michael A Weinreich, Jonathan J Lyons, Celeste G Nelson, Thomas DiMaggio, Kelly D Stone, Joshua D Milner Jeffrey R Stinson, Elisa Ruffo, Batsukh Dorjbal, Swadhinya Arjunaraja, Kelsey Voss, Andrew L Snow Jordan K Abbott, Pia J Hauk, Paul R Reynolds, Erwin W Gelfand Elisa Ruffo Salomé Glauzy, Natsuko Yamakawa, Eric Meffre Jennifer Stoddard, Julie Niemela, Sergio D Rosenzweig Yu Zhang, Helen F Matthews Joshua J McElwee Nina Jones Alejandro Palma, Matías Oleastro, Emma Prieto, Andrea R Bernasconi, Geronimo Dubra, Silvia Danielian, Jonathan Zaiat, Marcelo A Marti Brian Kim Megan A Cooper Neil Romberg | 2017 | 现代生物医学进展2017，17，27： | 3 |
| 4 | Interleukin- 18 binding protein: a novel modulator of the Th1 cytokine response显示文摘 | Novick D Kim SH Fantuzzi G | | 0，，： | 2 |
| 5 | 显示文摘 | Jang G H Hong S J Kim D K | 2000 | IEEE Transactions On Magnetics2000，36，5： | 2 |
| 6 | Oxidation of either methionine 351 or methionine 358 in alpha-1-antitrypsin causes loss of anti-neutrophil elastase activity显示文摘 | Taggart C Cervantes-Laurean D Kim G | 2000 | J Biol Chem2000，275，27： | 1 |
| 7 | Improved serpentine laminating micromixer with enhanced local advection显示文摘 | PARK J M KIM D S KANG T G | 2008 | Microfluidics and Nanofluidics2008，4，6： | 1 |
| 8 | Radium tracing of submarine groundwater discharge (SGD) and associated nutrient fluxes in a highly-permeable bed coastal zone, Korea 显示文摘 | Kim G Ryu J W Hwang D W | 2008 | Marine Chemistry2008，，109： | 1 |
| 9 | A thermal elastic-plastic finite-element analysis to roll-life prediction on the twin rol strip continuous casting process 显示文摘 | Kang C G Kim Y D | 1997 | Metallurgical and Materials Transactions B1997，28，12： | 1 |
| 10 | Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid 显示文摘 | Mucida D Park Y Kim G | 2007 | Science2007，317，5835： | 1 |
| 11 | Aciraetobacterpneumonia:a review显示文摘 | Hartzell J D Kim A S Kortepeter M G | 2007 | Med Gen Med2007，9，3： | 1 |
| 12 | Hydrogen-reduction behavior and microstructural characteristics of WO3-CuO powder mixtures with various milling time显示文摘 | Oh S T Jeon H | 2003 | Journal of Alloys and Compounds2003，，354： | 1 |
| 13 | Nonradioactive method to study genetic profiles of natural bacterial comunities by PCR-single-strand-conformation polymorphism显示文摘 | Lee D H Zo Y G Kim S J | 1996 | Appl Environ Microbiol1996，62，： | 1 |
| 14 | Observation of electric-field induced Ni filamem channels in polycrystalline NiOx film 显示文摘 | Park G S Li X S Kim D C | 2007 | Applied Physics Letters2007，91，22： | 1 |
| 15 | Improvement of 4I11/2→4I13/2 transition rate and thermal stabilities in Er3+-doped TeO2-B2O3-(GeO2)ZnO-K2O Glasses 显示文摘 | Cho D H Choi Y G Kim K H | 2001 | ETRI Joural(S1225-6463)2001，2，4： | 1 |
| 16 | Preparation of noble metal nanowires using hexagonal mesoporous silica SBA- 15 显示文摘 | Ham Y J Kim J M Stucky G D | 2000 | Chem Mater2000，12，： | 1 |
| 17 | Conductivity and Magnetoresistane of Polyacetylene Fiber Network显示文摘 | Kim G T Burghard M Suh D S | 1999 | Synth Met1999，105，： | 1 |
| 18 | Light and brassinosteroid signals are integrated via a dark-induced small G protein in etiolated seedling growth 显示文摘 | KANG J G YUN J KIM D H | 2001 | Cell2001，105，： | 1 |
| 19 | Comparison of AI-Cu-Fe quasierystalline particle reinforced AI composites fabricated by conventional casting and extrusion显示文摘 | Fleury E Lee S M Choi G Kim W T Kim D H | 2001 | J Mater Sci2001，36，： | 1 |
| 20 | Nanosized Sn-Cu-B alloy anode prepared by chemical reduction for secondary lithium batteries 显示文摘 | KIM D G KIM H SOHN H J | 2002 | J Power Sources2002，104，2： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员