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2篇 您的检索式:作者名="D.M.Parikh"
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1异环磷酰胺治疗晚期头颈部癌的Ⅱ期临床研究——大剂量单药治疗及异环磷酰胺-顺铂联合化疗显示文摘作者共收治128例病理证实的晚期和/或复发头颈癌。64例用异环磷酰胺(IFO)1.5g/m^2×5天治疗,58例可评价,其中6例CR,25例PR,总有效率53%;另外64例采用IFO1.5g/m^2和DDP10mg/m^2各5天联合化疗,54例可以评价,其中7例CR,29例PR,总有效率67%。每4星期重复疗程,每例病人接受3疗程化疗。所有病人均可见到不同程度恶心、呕吐、脱发和白细胞下降。V.R.PAI D.M.PARIKH A.T.MAZUMDAR R.S.RAO 黄慧强 1992癌症1992,11,3:4
2Pareto optimization of WEDM process parameters for machining a NiTi shape memory alloy using a combined approach of RSM and heat transfer search algorithm显示文摘Machining of shape memory alloys(SMAs)without losing the shape memory effect could immensely extend their applications.Herein,the wire electric discharge machining process was used to machine NiTi—a shape memory alloy.The experimental methodology was designed using a Box-Behnken design approach of the response surface methodology.The effects of input variables including pulse on time,pulse off time,and current were investigated on the material removal rate,surface roughness,and microhardness.ANOVA tests were performed to check the robustness of the generated empirical models.Optimization of the process parameters was performed using a newly formulated,highly efficient heat transfer search algorithm.Validation tests were conducted and extended for analyzing the retention of the shape memory effect of the machined surface by differential scanning calorimetry.In addition,2D and 3D Pareto curves were generated that indicated the trade-offs between the selected output variables during the simultaneous output variables using the multi-objective heat transfer search algorithm.The optimization route yielded encouraging results.Single objective optimization yielded a maximum material removal rate of 1.49 mm^(3)/s,maximum microhardness 462.52 HVN,and minimum surface roughness 0.11μm.The Pareto curves showed conflicting effects during the wire electric discharge machining of the shape memory alloy and presented a set of optimal non-dominant solutions.The shape memory alloy machined using the optimized process parameters even indicated a shape memory effect similar to that of the starting base material.Rakesh Chaudhari Jay J.Vora S.S.Mani Prabu I.A.Palani Vivek K.Patel D.M.Parikh 2021Advances in Manufacturing2021,9,1:0
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