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| 1 | The impact of patient expectations on outcome following treatment for spinal trauma (part 1): What are spine surgeons telling their patients? 显示文摘 | Darin Davidson Marcel F Dvorak A | 2010 | Soine2010,35,19: | 1 |
| 2 | Comparison of the effectiveness of passive (dam) ver- sus active (piglet) immunization against porcine cir covirus type 2 (PCV2) and impact of passively de- rived PCV2 vaccine-induced immunity on vaccination 显示文摘 | OPRIESSNIG A PATTERSON A DARIN M | 2009 | Vet Microhiol2009,,10: | 1 |
| 3 | Autosomal dominant myupathy : missense mutation ( Glu-706 - > Lys ) in the mysin heavy chain Ⅱ a gene显示文摘 | Martiusson T Oldfors A Darin N | 2000 | Proc Natl Aead Sci USA2000,97,14: | 1 |
| 4 | The incidence of mitochondrial encephalomyopathies in childhood: clinical features and morphological,biochemical, and DNA abnormalities 显示文摘 | Darin N Oldfors A Moslemi AR | 2001 | Ann Neurol2001,49,3: | 1 |
| 5 | Increased childhood incidence of narcolepsy in western Sweden after H1N1 influenza vaccination显示文摘 | Szakács A Darin N Hallbk T | 2013 | Neurology2013,80,14: | 1 |
| 6 | Efficacy and safety of non-vitamin K antagonist oral anticoagulants post-kidney transplantation显示文摘BACKGROUND Novel oral anticoagulants(NOACs)were developed as alternatives to vitamin K antagonists,primarily warfarin,as they do not require routine monitoring and have limited drug-drug and drug-food interactions.However,the efficacy and safety of these agents in kidney transplantation are not well studied.AIM To assess the profile and safety of NOACs for patients who had kidney transplantation,and to provide recommendations and guidelines on therapeutic strategies in these patients.METHODS This was a retrospective study carried out among adult patients who were actively on the following NOACs(apixaban,rivaroxaban or dabigatran)in our renal transplantation program from December 2015 to December 2016.The patients were identified primarily through electronic medical record system(patient data linkage).Data on the clinical and laboratory profile of the patients were retrieved and analyzed with SPSS 22.0.RESULTS Complete data on 42 renal transplant patients were retrieved:59.5%males,90.5%were whites and 66.7%were older than 60 years old.The mean duration since renal transplantation of the patients was 8.8±7.4 years.The most common risk factors for the development of end-stage renal disease in the subjects were hypertension(19.0%),polycystic kidney disease(19.0%),followed by diabetic nephropathy(16.7%)and chronic glomerulonephritis(16.7%).The main indications for NOACs use in the cohort were atrial fibrillation in 25 patients(59.5%)and venous thromboembolism in 10 patients(23.8%).Overall,29 patients(69%)were treated with apixaban,10 patients(23.8%)with rivaroxaban and 3 patients(7.14%)with dabigatran.No(0%)thromboembolic events were observed during the one-year period,but 3(7.1%)bleeding events occurred in the cohort consisting of 1 patient treated with rivaroxaban 15 mg daily and 2 patients who received apixaban 2.5 mg twice daily.There were no significant changes in serum tacrolimus level three days after the initiation of NOACs among patients treated with tacrolimus(pre-and post-NOACs tacrolimus levels were 7.2516 and 7.8867 ng/m L,P=0.55,respectively).Also,after one-year of treatment with NOACs there were no significant changes in the pre-and post-NOACs serum creatinine level(P=0.772)and estimated glomerular filtration rates(P=0.232).CONCLUSION No thromboembolic events or significant changes in renal profile were observed in our cohort of kidney transplant recipients who were treated with NOACs for at least a year.However,a few bleeding events were observed.This calls for further well-planned randomized controlled trials to assess the efficacy and safety of NOACs among renal transplant recipients. | Muhammad A Bukhari Abdulrahman Al-Theaby Mohammed Tawhari Ali Al-Shaggag Ryan Pyrke Azim Gangji Darin Treleaven Christine Ribic | 2019 | World Journal of Transplantation2019,9,6: | 1 |
| 7 | Cerebral metabolic correlates as potential predictors of response to anterior cingulotomy for obsessive compulsive disorder显示文摘 | Scott L Rauch Darin D Dougherty G.Rees Cosgrove Edwin H Cassem Nathaniel M Alpert Bruce H Price Andrew A Nierenberg Helen S Mayberg Lee Baer Michael A Jenike Alan J Fischman | 2001 | Biological Psychiatry2001,,9: | 1 |
| 8 | Metabolism of(+)- 1,4-Dihydro-7-(trans-3-methoxy-4-methylamino- l-pyrrolidinyl)-4-oxo- 1 -(2-thiazolyl)-1,8-naphthyridine-3-carboxytic Acid (Voreloxin; Formerly SNS- 595), a Novel Replication-Dependent DNA-Damaging Agent显示文摘 | Marc J E Darin A Josh C Y | 2009 | The American Society for Pharmacology and Experimental Therapeutics2009,37,3: | 1 |
| 9 | Ircreased dicarbonyl metabolism in endothelial cells in increased dicarbonyl metabolism in endothelial cells显示文摘 | Darin D Naila A Song L J | 2006 | Diabetes2006,55,7: | 1 |
| 10 | Increased childhood incidence of narcolepsy in wester Sweden after H1N1 influenza vaccina- tion显示文摘 | Szakacs A Darin N Hallbook T | 2013 | Neurology2013,80,14: | 1 |
| 11 | Myopathies associated with myosin heavy chain mutations显示文摘 | Oldfors A Tajsharghi H Darin N | 2004 | Acta Myol2004,23,2: | 1 |
| 12 | The incidence of mitochondrial encephalomyopathies in childhood: clinical features and morphological, biochemical, and DNA abnormalities 显示文摘 | Darin N Oldfors A Moslemi AR | 2001 | Ann Neurol2001,49,3: | 1 |
| 13 | Stroke health and risk education (SHARE) pilot project: feasibility and need for church-based stroke health promotion in a bi-ethnic community显示文摘 | Darin B Zahuranec Lewis B Morgenstem Nelda M Garcia Kathleen M Conley Lynda D Lisabeth Grace S Rank Melinda A Smith William J Meurer Ken Resnicow Devin L Brown | 2008 | Stroke a journal of cerebral circulation2008,39,5: | 1 |
| 14 | The incidence of mitochondrial encephalomyopathies in childhood:clinical features and morphological,biochemical,and DNA abnormalities显示文摘 | Darin N Oldfors A Moslemi AR | | 0,,: | 1 |
| 15 | Chemical composition and antifungal activity of Illicium verum and Eugenia caryophyllata essential oils 显示文摘 | DARINE A SOKOVIC M RISTIC M S | 2009 | Chem Nat Comp2009,45,2: | 1 |
| 16 | Analysis of cyclic loading of plane R/C structures显示文摘 | Darin D Pecknold D A W | 1977 | Computers and Structures1977,7,: | 1 |
| 17 | Novel mutations in the thymidine kinase 2 gene ( TK2 ) associated with fatal mitochondrial myopathy and mitochondrial DNA depletion 显示文摘 | Tulinius M Maslemi A R Darin N | 2005 | Neuromuscul Disord2005,15,6: | 1 |
| 18 | Capillary electrochromatography with monolithic silica columns: III Preparation of hydrophilic silica monoliths having surface-bound cyano groups: chromatographic characterization and application to the separation of carbohydrates, nucleosides, nucleic acid bases and other neutral polar species 显示文摘 | DARIN A ZIAD E R | 2004 | J Chromatogr A2004,1029,23: | 1 |
| 19 | Population-based analysis of the impact of expanding the time window for acute strok treatment显示文摘 | Jennifer J M Melinda A S Darin B Z | 2007 | Stroke2007,38,12: | 1 |
| 20 | POLG1 muta-tions associated with progressive encephalopathy in childhood显示文摘 | KOLLBERG G MOSLEMI A R DARIN N | 2006 | J Neuropathol Exp Neurol2006,65,8: | 1 |