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| 1 | Factor analysis identifies subgroups of constipation显示文摘AIM:To determine whether distinct symptom groupings exist in a constipated population and whether such grouping might correlate with quantifiable pathophysiological measures of colonic dysfunction.METHODS:One hundred and ninety-one patients presenting to a Gastroenterology clinic with constipation and 32 constipated patients responding to a newspaper advertisement completed a 53-item,wide-ranging selfreport questionnaire.One hundred of these patients had colonic transit measured scintigraphically.Factor analysis determined whether constipation-related symptoms grouped into distinct aspects of symptomatology.Cluster analysis was used to determine whether indi-vidual patients naturally group into distinct subtypes.RESULTS:Cluster analysis yielded a 4 cluster solution with the presence or absence of pain and laxative unresponsiveness providing the main descriptors.Amongst all clusters there was a considerable proportion of patients with demonstrable delayed colon transit,irritable bowel syndrome positive criteria and regular stool frequency.The majority of patients with these characteristics also reported regular laxative use.CONCLUSION:Factor analysis identified four constipation subgroups,based on severity and laxative unresponsiveness,in a constipated population.However,clear stratification into clinically identifiable groups remains imprecise. | Philip G Dinning Mike Jones Linda Hunt Sergio E Fuentealba Jamshid Kalanter Denis W King David Z Lubowski Nicholas J Talley Ian J Cook | 2011 | World Journal of Gastroenterology2011，17，11： | 3 |
| 2 | Entrepreneurial finance:An overview of the issues and evidence显示文摘 | DAVID J DENIS | 2004 | Journal of Corporate Finance2004，，10： | 1 |
| 3 | Leverage and Investment in Diversified Finns 显示文摘 | Ahn Seoungpil Denis David J | 2006 | Journal of Financial Economics2006，，79： | 1 |
| 4 | Managerial Discretion, Organizational Structure, and Corporate Performance : A Study of Leveraged Recapitalizations 显示文摘 | David J Denis Diane K Denis | 1993 | Journal of Accounting and Economics1993，16，13： | 1 |
| 5 | Financial Constraints, In- vestment, and the Value of Cash Holdings 显示文摘 | Denis David J Sibilkov Valeriy | 2010 | Review of Fiancial Studies2010，23，1： | 1 |
| 6 | Agency Problems, Equity Wwnership and Corporate Diversification 显示文摘 | Denis David J Diane Denis Atula Satin | 1997 | Journal of Finance1997，52，1： | 1 |
| 7 | The Choice Among Bank Debt, Non-bank Private Debt, and Public Debt: Evidence from new Corporate Borrowings显示文摘 | David J Denis Vassil T Mihov | 2003 | Journal of Financial Economics2003，70，1： | 1 |
| 8 | Agency problems, equity ownership and corporate diversification显示文摘 | Denis David J Diane Denis Atulya Satin | 1997 | Journal of Finance1997，，52： | 1 |
| 9 | Agency problems,equity ownership and corporate diversification显示文摘 | Denis David J Diane Denis Atulya Sarin | 2002 | Journal of Finance2002，1，52： | 1 |
| 10 | Financial Constraints, Investment, and the Value of Cash Holdings 显示文摘 | Denis David J Sibilkov Valeriy | 2010 | The Review of Finance Studies2010，23，1： | 1 |
| 11 | The choice among bank debt, non-bank private debt, and public debt: evidence from new corporate borrowings显示文摘 | David J Denis Vassil T Mihov | 2003 | Journal of Financial Economics2003，，1： | 1 |
| 12 | Managerial discre- tion, organizational structure, and corporate performance : a study of leveraged recapitalizations显示文摘 | DAVID J DENIS DIANE K DENIS | 1993 | Journal of Account- ing and Economics1993，16，13： | 1 |
| 13 | Financial con- straints,investment, and the value of cash holdings显示文摘 | DAVID J DENIS VALERIY SIBILKOV | 2010 | The Review of Financial Studies2010，23，1： | 1 |
| 14 | Internal capital markets and investment policy evidence from corporate spinoffs显示文摘 | Seoungpil Ahn David J Denis | 2004 | Journal of Financial Economics2004，71，： | 1 |
| 15 | Internal capital markets and investment policy: Evidence from corporate spinoffs显示文摘 | Ahn S and Denis David J | 2002 | Journal of Financial Economics2002，71，1： | 1 |
| 16 | Managerial Discretion, Organizational Structure, and Corporate Performance: A Study of Leveraged Recapitalizations显示文摘 | David J Denis Diane K Denis | 1993 | Jouranl of Accounting and Economics1993，16，13： | 1 |
| 17 | Ownership and board structures in publicly traded corporations显示文摘 | David J Denis Atulya Sarin | 1999 | Journal of Financial Economics1999，，2： | 1 |
| 18 | N,N-disubstituted 2-amino thiazole-5-carboxaldehydes:preparation and investigation of structural features显示文摘 | David W Gillon Lan J Forrest G Denis Meakins | 1983 | J Chem Soc Pe rkin Transl1983，，2： | 1 |
| 19 | Structural, thermal, and spectral characterization of the different crystalline forms of Alq3, tris( quinolin-8-ola- to) aluminum( Ⅲ), an electroluminescent material in OLED technology 显示文摘 | Rajeswaran Manju Blanton Thomas N Tang Ching W Lenhart William C Switalski Steven C Giesen David J Antalek Brian J Pawlik Thomas D Kondakov Denis Y Nicholas Zumbulyadis Young Ralph H | 2009 | Polyhedron2009，28，： | 1 |
| 20 | Ownership and board structures in publicly traded corporations显示文摘 | David J Denis Atulya Sarin | 1999 | Journal of Financial Economics1999，，2： | 1 |
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