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| 1 | 光激酶C基因突变导致的大头精子畸形是阿尔及利亚男性不育症的最常见遗传因素显示文摘克氏综合征和Y染色体微缺失是过去针对男性不育症仅有的两项基因检测分析技术。北非男性经常出现两种罕见的畸形精子症:大头和圆头精子畸形,推荐进行AURKC和DPYl9L2基因检测。对阿尔及利亚男性不育患者进行以上基因检测,评估两种畸形精子症的患病率,并与克氏综合征和Y染色体微缺失的频率进行比较。我们对阿尔及利亚君士坦丁市的IbnRochd医院辅助生殖中心进行不育症咨询的599名患者进行了回顾性研究,其中404人存在精液参数异常现象。14人和7人分别患有典型的大头精子畸形或圆头精子畸形,进而对这些患者进行了AURKC和DPYl9L2基因分析显示,11名大头精子畸形患者存在4URKC基因突变(79%),相当于所有精液异常人群的2.7%。而5名圆头精子畸形患者,相当于1.2%的不育症患者,均存在DPYl9L2基因缺失。通过比较,我们预测该人群中克氏综合症和Y染色体微缺失的患病率分别是1.6%和0.23%。我们的研究表明AURKC基因突变较克氏综合症更常见,它是导致北非男性不育的主要遗传因素。此外,本文也预测了AURKC和DP"觋2基因缺陷发生率分别是Y染色体微缺失发生率的10倍和5倍。 | Leyla Ounis Abdelali Zoghmar Charles Coutton Leila Rouabah Maroua Hachemil Delphine Martinez Guillaume Martinez Ines Bellil Douadi Khelifi Christophe Arnoult Julien Faure Sebti Benbouhedja Abdelkader Rouabah Pierre F Ray | 2015 | Asian Journal of Andrology2015，17，1： | 5 |
| 2 | High-performance waveguide-integrated germanium PIN photodiodes for optical communication applications[Invited]显示文摘This paper reports on high-performance waveguide-integrated germanium photodiodes for optical communications applications.200 mm wafers and production tools were used to fabricate the devices.Yields over 97%were obtained for three different compact photodiodes(10×10μm and intrinsic region width of 0.5,0.7,and 1μm)within the same batch of three wafers.Those photodiodes exhibit low dark currents under reverse bias with median values of 74,62,and 61 nA for intrinsic widths of 0.5,0.7,and 1μm,respectively,over a full wafer.Responsivities up to 0.78 A∕W at 1550 nm and zero bias were measured.Zero bias operation is possible for 25 and 40 Gbps with receiver sensitivity estimated to−13.9 and−12.3 dBm,respectively. | Léopold Virot Laurent Vivien Jean-Marc Fédéli Yann Bogumilowicz Jean-Michel Hartmann Frédéric Bœuf Paul Crozat Delphine Marris-Morini Eric Cassan | 2013 | Photonics Research2013，1，3： | 2 |
| 3 | 25 Gbps low-voltage hetero-structured silicongermanium waveguide pin photodetectors for monolithic on-chip nanophotonic architectures显示文摘Near-infrared germanium(Ge) photodetectors monolithically integrated on top of silicon-on-insulator substrates are universally regarded as key enablers towards chip-scale nanophotonics, with applications ranging from sensing and health monitoring to object recognition and optical communications. In this work, we report on the highdata-rate performance pin waveguide photodetectors made of a lateral hetero-structured silicon-Ge-silicon(Si-Ge-Si) junction operating under low reverse bias at 1.55 μm. The pin photodetector integration scheme considerably eases device manufacturing and is fully compatible with complementary metal-oxide-semiconductor technology. In particular, the hetero-structured Si-Ge-Si photodetectors show efficiency-bandwidth products of^9 GHz at-1 V and ~30 GHz at-3 V, with a leakage dark current as low as ~150 nA, allowing superior signal detection of high-speed data traffic. A bit-error rate of 10-9 is achieved for conventional 10 Gbps, 20 Gbps, and25 Gbps data rates, yielding optical power sensitivities of-13.85 dBm,-12.70 dBm, and-11.25 dBm, respectively. This demonstration opens up new horizons towards cost-effective Ge pin waveguide photodetectors that combine fast device operation at low voltages with standard semiconductor fabrication processes, as desired for reliable on-chip architectures in next-generation nanophotonics integrated circuits. | DANIEL BENEDIKOVIC LéOPOLD VIROT GUY AUBIN FARAH AMAR BERTRAND SZELAG BAYRAM KARAKUS JEAN-MICHEL HARTMANN CARLOS ALONSO-RAMOS XAVIER LE ROUX PAUL CROZAT ERIC CASSAN DELPHINE MARRIS-MORINI CHARLES BAUDOT FRéDéRIC BOEUF JEAN-MARC FéDéLI CHRISTOPHE KOPP LAURENT VIVIEN | 2019 | Photonics Research2019，7，4： | 2 |
| 4 | A shapley decomposition of carbon emissionswithout residuals 显示文摘 | Johan A Delphine F Koen S | 2002 | Energy Policy2002，30，： | 1 |
| 5 | A Shapley Decomposi- tion of Carbon Emissions Without Residuals显示文摘 | Johan A Delphine F Koen S | 2002 | En- ergy Policy2002，30，： | 1 |
| 6 | Magnetic iron oxide nanoparticles:synthesis,stabilization,vectorization,physicochem ical characte-rizations,and biological applications显示文摘 | SOPHIE L DELPHINE F ROBERT N M | 2008 | Chem Rev2008，108，6： | 1 |
| 7 | A shapley decomposition of carbon emissions without residuals显示文摘 | A JOHAN F DELPHINE S KOEN | | 0，，30： | 1 |
| 8 | A Shapley Decomposition of Carbon Emissions without Residuals显示文摘 | Johan A Delphine F Koen S | 2002 | Energy Policy2002，30，： | 1 |
| 9 | A Shapley Decomposition of Carbon Emission without Residuals 显示文摘 | Johan A Delphine F Koen S | 2002 | Energy Policy2002，30，： | 1 |
| 10 | A Shapley Decomposition of Carbon Emissions without Residuals显示文摘 | Johan A Delphine F Koen S | 2002 | Energy Policy2002，30，： | 1 |
| 11 | A Shapley Decomposition of Carbon Emissions without Residuals 显示文摘 | Johan A Delphine F Koen S | 2002 | Energy Policy2002，，30： | 1 |
| 12 | Structural analysis of new local features in SECIS RNA hairpins显示文摘 | Delphine F Alain L Robert W | 2000 | Nucleic Acids Res2000，28，14： | 1 |
| 13 | A Shapley Decomposition of Carbon Emissions without Residuals 显示文摘 | Johan A Delphine F Koen S | 2002 | Energy Policy2002，，： | 1 |
| 14 | Prevalence of Bordetella pertussis and Bordetella parapertussis infections in Tunisian hospitalized infants: results of a 4-year prospective study显示文摘 | Asma Zouari Hanen Smaoui Delphine Brun Elisabeth Njamkepo Soufien Sghaier Emna Zouari Renaud Félix Khaled Menif Najla Ben Jaballah Nicole Guiso Amel Kechrid | 2012 | Diagnostic Microbiology & Infectious Disease2012，，4： | 1 |
| 15 | The hepatitis B Virus X protein functionally interacts with CREB-binding protein/p300 in the regulation of CREB-mediated transcription显示文摘 | DELPHINE C WU Y F STEFANO C | 2007 | J Biol Chem2007，282，： | 1 |
| 16 | A Shapley decomposition of carbon emissions without residuals 显示文摘 | JOHAN A DELPHINE F KOEN S | 2002 | Energy Policy2002，，30： | 1 |
| 17 | A Shapley Decomposition of Carbo Enfissions without Residuals显示文摘 | Johan A Delphine F Koen S | 2002 | Energy Policy2002，30，： | 1 |
| 18 | A Shapley decomposition of carbon emissions without residuals 显示文摘 | JOHAN A DELPHINE F KOEN S | 2002 | Energy Policy2002，30，： | 1 |
| 19 | Shapley decomposi- tion of carbon emissions without residuals显示文摘 | JOHAN A DELPHINE F KOEN S A | 2002 | Energy Policy2002，30，： | 1 |
| 20 | A Shapley Decomposition of Carbon Emissions without Residuals 显示文摘 | Johan A Delphine F Koen S | 2002 | Energy Policy2002，30，： | 1 |
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