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4篇 您的检索式:作者名="DEMIREL Ufuk"
    题名 作者 年代 出处 被引量
1Macroeconomic stabilization in developing economies:Are optimal policies procyclical显示文摘Ufuk Devrim Demirel 0,,:1
2A microarray based expression profiling of paclitaxel and vincristine resistant MCF-7 cells显示文摘Meltem Demirel Kars ?zlem Darcansoy I?eri Ufuk Gündüz 2010European Journal of Pharmacology2010,,1:1
3Exploring a natural MDR reversal agent: potential of medicinal food supplement Nerium oleander leaf distillate显示文摘Objective:To investigate the molecular effects ofNerium oleanderleaf distillate on paclitaxel and vincristine resistant(MCF-7/Pac and MCF-7/Vinc)cells and sensitive(MCF-7/S)cell lines.Methods:Nerium oleander(N.oleander)leaf extract was obtained by hydrodistillation method.The toxicological effects ofN.oleanderdistillate,previously suggested as medicinal food supplement,on drug resistant cells were evaluated by XTT tests.MDR modulation potential of the plant material was evaluated by flow cytometry and fluorescent microscopy.Paclitaxel and vincristine were applied to the sublines in combination with N.oleanderdistillate.Results:Fractional inhibitory indices show thatN.oleanderdistillate did not increase the antiproliferative effects of anticancer drugs.N.oleandertreatment in to MCF-7/Pac and MCF-7/Vinc did not inhibit P-gp activity and MDR1 gene expression level.Conclusions:As a result it may be suggested that althoughN.oleanderdistillate has some medicinal effects as food supplement it may not be suitable as an MDR modulator for drug resistant breast cancer cells.Meltem Demirel Kars Ufuk Gündüz Kamilüney AhmetLevent Ba 2013Asian Pacific Journal of Tropical Biomedicine2013,3,8:1
4Heat Stress Related Gene Expression in Gossypium hirsutum L.显示文摘Abiotic stress is a major limiting factor to crop productivity,and heat stress is one of the important elements for reduced crop production.Plants respond to heat stress at molecular and cellular levels as well as physiological level.Heat stress alters expression patterns of numerous genes in plants.DEMIREL Ufuk GR M Atilla KARAKU Mehmet MEMON Abdul Rezaque 2008棉花学报2008,20,S1:0
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