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| 1 | Nutritional care in hospitalized patients with chronic liver disease显示文摘AIM: To evaluate the practice of nutritional assessment and management of hospitalised patients with cirrhosis and the impact of malnutrition on their clinical outcome.METHODS: This was a retrospective cohort study on patients with liver cirrhosis consecutively admitted to the Department of Gastroenterology and Hepatology at the Royal Adelaide Hospital over 24 mo. Details were gathered related to the patients' demographics, disease severity, nutritional status and assessment, biochemistry and clinical outcomes. Nutritional status was assessed by a dietician and determined by subjective global assessment. Estimated energy and protein requirements were calculated by Simple Ratio Method. Intake was estimated from dietary history and/or food charts, and represented as a percentage of estimated daily requirements. Median duration of follow up was 14.9(0-41.4) mo. RESULTS: Of the 231 cirrhotic patients(167 male, age: 56.3 ± 0.9 years, 9% Child-Pugh A, 42% ChildPugh B and 49% Child-Pugh C), 131(57%) had formal nutritional assessment during their admission and 74(56%) were judged to have malnutrition. In-hospitalcaloric(15.6 ± 1.2 kcal/kg vs 23.7 ± 2.3 kcal/kg, P = 0.0003) and protein intake(0.65 ± 0.06 g/kg vs 1.01 ± 0.07 g/kg, P = 0.0003) was significantly reduced in patients with malnutrition. Of the malnourished cohort, 12(16%) received enteral nutrition during hospitalisation and only 6(8%) received ongoing dietetic review and assessment following discharge from hospital. The overall mortality was 51%, and was higher in patients with malnutrition compared to those without(HR = 5.29, 95%CI: 2.31-12.1; P < 0.001). CONCLUSION: Malnutrition is common in hospitalised patients with cirrhosis and is associated with higher mortality. Formal nutritional assessment, however, is inadequate. This highlights the need for meticulous nutritional evaluation and management in these patients. | Dep K Huynh Shane P Selvanderan Hugh AJ Harley Richard H Holloway Nam Q Nguyen | 2015 | World Journal of Gastroenterology2015，21，45： | 6 |
| 2 | A fast and elitist multi - objective genetic algorithm : NSGA - Ⅱ 显示文摘 | DEP K PRATAP A AGARWAL S | 2002 | IEEE Transactions on Evolutionary Computation2002，6，2： | 1 |
| 3 | Dei ning pathways显示文摘 | De Bleser L Dep reitere R De Waele K | 2006 | Nurs M2006，14，7： | 1 |
| 4 | A dominant-negative isoform of hypoxia-inducible factor-1 alpha specifically expressed in human testis显示文摘 | Depping R Hagele S Wagner K F | 2004 | Biol Reprod2004，71，1： | 1 |
| 5 | Expression of the erythropoietin receptor in human heart显示文摘 | Depping R Kawakami K Ocker H | 2005 | J Tberac Cardiovasc Surg2005，130，3： | 1 |
| 6 | Defining pathways显示文摘 | De Bleser L Dep reitere R De Waele K | 2006 | Nurs M2006，14，7： | 1 |
| 7 | Second-generation antipsychotics for anxiety disorders 显示文摘 | Depping AM Komossa K Kissling W | 2010 | Cochr Datab Syst Rev2010，，00： | 1 |
| 8 | Defining pathways显示文摘 | De Bleser L Dep reitere R De Waele K | 2006 | Nurs M2006，14，7： | 1 |
| 9 | Second-generation antipsychotics for obsessive compulsive disorder显示文摘 | Komossa K Depping A M Meyer M | 2010 | Coehrane Database Syst Rev2010，12，00： | 1 |
| 10 | Expression of the erythropoietin receptor in human heart 显示文摘 | Depping R Kawakami K Ocker H | 2005 | J Thorac Cardiovasc Surg2005，130，： | 1 |
| 11 | Defining pathways显示文摘 | De Bleser L Dep reitere R De Waele K | 2006 | JNursManag2006，14，7： | 1 |
| 12 | Second-generation antipsychotics for obsessive compulsive disorder显示文摘 | Komossa K Depping AM Meyer M | 2010 | Cochrane Database Syst Rev2010，12，00： | 1 |
| 13 | Defining pathways显示文摘 | De Bleser L Dep reitere R De Waele K | 2006 | Nurs M2006，14，7： | 1 |
| 14 | Expression of the erythropoietin receptor in human heart显示文摘 | Depping R Kawakami K Ocker H | 2005 | Thorac Cardiovasc Surg2005，130，3： | 1 |
| 15 | A dominant-negative isoform of hypoxia-inducible factor-1(specifically expressed in human testis显示文摘 | DEPPING R GELE S H WAGNER K F | 2004 | Biol Rep2004，19，71： | 1 |
| 16 | Expression of the erythropoietin receptor in human heart显示文摘 | DEPPING R KAWAKAMI K OCKER H | 2005 | J Thorac Cardiovasc Surg2005，130，3： | 1 |
| 17 | Defining pathways显示文摘 | De Bleser L Dep reitere R De Waele K | 2006 | Nuts M2006，14，7： | 1 |
| 18 | Polyphenol oxidase and photosynthesis research 显示文摘 | Trebst A Dep K B | 1995 | Photosynthesis Research1995，46，： | 1 |
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