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| 1 | Occurrence of retained placenta is preceded by an inflammatory state and alterations of energy metabolism in transition dairy cows显示文摘Background: Failure to expel fetal membranes within 24 h of calving is a pathological condition defined as retained placenta(RP). The objective of this investigation was to evaluate whether there are alterations in several selected serum variables related to innate immunity and carbohydrate and lipid metabolism that precede occurrence of RP in transition Holstein dairy cows.Methods: One hundred multiparous Holstein dairy cows were involved in the study. Blood samples were collected from the coccygeal vein during the-8 to +4 wks around parturition, once per week before the morning feeding.Six healthy control cows(CON) and 6 cows with RP were selected and serum samples at-8,-4, time of diagnosis of disease, and +4 wks relative to parturition were used for analyses. All samples were analyzed for lactate, nonesterified fatty acids(NEFA), β-hydroxybutyrate(BHBA), interleukin-1(IL-1), interleukin-6(IL-6), tumor necrosis factor(TNF), haptoglobin(Hp), and serum amyloid A(SAA).Results: Cows with RP had greater concentrations of serum lactate, IL-1, IL-6, TNF, and SAA in comparison with CON cows. Intriguingly, elevated concentrations of all five variables were observed at-8 and-4 wks before the occurrence of RP compared to healthy cows. Cows with RP also had lower DMI and milk production vs CON animals; however milk composition was not affected by RP.Conclusions: Cows with RP showed an activated innate immunity 8 wks prior to diagnosis of disease. Overall results suggest that serum IL-1, IL- 6, and TNF, and lactate can be used as screening biomarkers to indicate cows that might have health issues during the transition period. | Elda Dervishi Guanshi Zhang Dagnachew Hailemariam Suzana M.Dunn Burim N.Ametaj | 2016 | Journal of Animal Science and Biotechnology2016，7，3： | 2 |
| 2 | The effect of feeding system in the expression of genes related with fat metabolism in semitendinous muscle in sheep显示文摘 | Dervishi E Serrano C Joy M | 2011 | Meat Science2011，89，1： | 1 |
| 3 | Antioxidant and chemopreventive properties of polyphenolic compounds derived from Greek legume plant extracts显示文摘 | Spanou C Bourou G Dervishi A | 2008 | Joumal of Agricultural and Food Chemistry2008，56，16： | 1 |
| 4 | Carbon nanotubes are able to penetrate plant seed coat and dramatically affect seed germination and plant growth显示文摘 | Khodakovskaya M Dervishi E Mahmood M | 2009 | ACS Nano2009，3，10： | 1 |
| 5 | Large-seale graphene production by RF-cCVD method显示文摘 | DERVISHI E ZHONGRUI L WATANABE F | 2009 | Chemical Commu- nications2009，，27： | 1 |
| 6 | Cytotoxicity effects of graphene and single-wall carbon nanotubes in neural phaeochromocytoma-de- rived PC12 ceils显示文摘 | Zhang Y Ali SF Dervishi E | 2010 | Acs Nano2010，4，6： | 1 |
| 7 | The effect of feeding system in the expression of genes re- lated with fat metabolism in semitendinous muscle in sheep显示文摘 | DERVISHI E SERRANO C JOY M | 2011 | MeatSci2011，89，1： | 1 |
| 8 | Carbon Nanotubes: Synthe- sis, Properties, and Applications显示文摘 | Dervishi E Li Z Xu Y | 2009 | Particulate Science and Technology2009，27，2： | 1 |
| 9 | Carbon nanotubes are able to penetrate plant seed coat and dramatically affect seed germination and plant growth 显示文摘 | Khodakovskaya M Dervishi E Mahmood M | 2009 | ACS Nano2009，3，10： | 1 |
| 10 | Carbon nanotubes are able to penetrate plant seed coat and dramatically affect seed germination and plant growth显示文摘 | Khodakovskaya M Dervishi E Mahnood M | | 0，，10： | 1 |
| 11 | Cytotoxicity effects of graphene and single - wall carbon nanotubes in neural phaeochromocytoma - derived 19C12 cells显示文摘 | Ali S F Dervishi E Xu Y Li Z | 2010 | Acs Nano2010，4，6： | 1 |
| 12 | Carbon nanotubes are able to penetrate plant seed coat and dramatically 'affect seed germination and plant growth显示文摘 | KHODAKOVSKAYA M DERVISHI E MAHMOOD M | 2009 | ACS Nano2009，3，10： | 1 |
| 13 | Does the wall num-ber of carbon nanotubes matter as conductive transparent material显示文摘 | Li Z R Kandel H R Dervishi E | 2007 | Appl Phys Lett2007，91，05： | 1 |
| 14 | Carbon nanotubes are able to penetrate plant seed coat and dramatically affect seed germination and plant growth显示文摘 | Khodakovskaya M Dervishi E Mahmood M | | 0，，10： | 1 |
| 15 | Carbon nanotubes are able to penetrate plant seed coat and dramatically affect seed germination and plant growth显示文摘 | Khodakovskaya M Dervishi E Mahmood M Xu Y Li Z Watanabe F Biris A S | | 0，，10： | 1 |
| 16 | Comparative Study on Different Caibon Nanotube Materials in Terms of Transparent Conductive Coatings 显示文摘 | Li Z Rt Kandel H R Dervishi E | 2008 | Langmuir2008，24，6： | 1 |
| 17 | The effect of feeding system inthe expression of genes related with fat metabolism in semitendinousmuscle in sheep显示文摘 | Dervishi E Serrano C Joy M | 2011 | Meat Sci2011，89，1： | 1 |
| 18 | 显示文摘 | Zhang Y B Ali S F Dervishi E | 2010 | ACS Nano2010，4，6： | 1 |
| 19 | Cytotoxicity effects of graphene and single-wall carbon nanotubes in neural phaeochromocytoma-derived pcl2 cells显示文摘 | Zhang Y All S F Dervishi E | 2010 | ACS Nano2010，4，6： | 1 |
| 20 | Cytotoxicity effects of graph- ene and single-wall carbon nanotubes in neural phaeochromoc- ytoma-derived PC12 cells显示文摘 | Zhang Y Ali SF Dervishi E | 2010 | ACS Nano2010，4，6： | 1 |
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