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| 1 | Physical rehabilitation for lung transplant candidates and recipients: An evidence-informed clinical approach显示文摘Physical rehabilitation of lung transplant candidates and recipients plays an important in optimizing physical function prior to transplant and facilitating recovery of function post-transplant. As medical and surgical interventions in lung transplantation have evolved over time, there has been a demographic shift of individuals undergoing lung transplantation including older individuals, those with multiple co-morbidites, and candidates with respiratory failure requiring bridging to transplantation. These changes have an impact on the rehabilitation needs of lung transplant candidates and recipients. This review provides a practical approach to rehabilitation based on research and clinical practice at our transplant centre. It focuses on functional assessment and exercise prescription during an uncomplicated and complicated clinical course in the pre-transplant, early and late post-transplant periods. The target audience includes clinicians involved in pre- and posttransplant patient care and rehabilitation researchers. | Lisa Wickerson Dmitry Rozenberg Tania Janaudis-Ferreira Robin Deliva Vincent Lo Gary Beauchamp Denise Helm Chaya Gottesman Polyana Mendes Luciana Vieira Margaret Herridge Lianne G Singer Sunita Mathur | 2016 | World Journal of Transplantation2016，6，3： | 8 |
| 2 | What operation for recurrent rectal prolapse after previous Delorme's procedure? A practical reality显示文摘AIM: To report our experience with perineal repair(Delorme's procedure) of rectal prolapse with particular focus on treatment of the recurrence.METHODS: Clinical records of 40 patients who underwent Delorme's procedure between 2003 and 2014 were reviewed to obtain the following data: Gender; duration of symptoms, length of prolapse, operation time, ASA grade, length of post-operative stay, procedure-related complications, development and treatment of recurrent prolapse. Analysis of post-operative complications, rate and time of recurrence and factors influencing the choice of the procedure for recurrent disease was conducted. Continuous variables were expressed as the median with interquartile range(IQR). Statistical analysis was carried out using the Fisher exact test.RESULTS: Median age at the time of surgery was 76 years(IQR: 71-81.5) and there were 38 females and 2 males. The median duration of symptoms was 6 mo(IQR: 3.5-12) and majority of patients presented electively whereas four patients presented in the emergency department with irreducible rectal prolapse. The median length of prolapse was 5 cm(IQR: 5-7), median operative time was 100 min(IQR: 85-120) and median post-operative stay was 4 d(IQR: 3-6). Approximately16% of the patients suffered minor complications such as- urinary retention, delayed defaecation and infected haematoma. One patient died constituting postoperative mortality of 2.5%. Median follow-up was 6.5 mo(IQR: 2.15-16). Overall recurrence rate was 28%(n = 12). Recurrence rate for patients undergoing an urgent Delorme's procedure who presented as an emergency was higher(75.0%) compared to those treated electively(20.5%), P value 0.034. Median time interval from surgery to the development of recurrence was 16 mo(IQR: 5-30). There were three patients who developed an early recurrence, within two weeks of the initial procedure. The management of the recurrent prolapse was as follows: No further intervention(n = 1), repeat Delorme's procedure(n = 3), Altemeier's procedure(n = 5) and rectopexy with faecal diversion(n = 3). One patient was lost during follow up.CONCLUSION: Delorme's procedure is a suitable treatment for rectal prolapse due to low morbidity and mortality and acceptable rate of recurrence. The management of the recurrent rectal prolapse is often restricted to the pelvic approach by the same patientrelated factors that influenced the choice of the initial operation, i.e., Delorme's procedure. Early recurrence developing within days or weeks often represents a technical failure and may require abdominal rectopexy with faecal diversion. | Muhammad A Javed Faryal G Afridi Dmitri Y Artioukh | 2016 | World Journal of Gastrointestinal Surgery2016，8，7： | 4 |
| 3 | Value of two-phase dynamic multidetector computed tomography in differential diagnosis of post-inflammatory strictures from esophageal cancer显示文摘AIM: To characterize the computed tomography(CT) findings in patients with post-inflammatory esophageal strictures(corrosive and peptic) and reveal the optimal scanning phase protocols for distinguishing postinflammatory esophageal stricture and esophageal cancer.METHODS: Sixty-five patients with esophageal strictures of different etiology were included in this study: 24 patients with 27 histopathologically confirmed corrosive strictures, 10 patients with 12 peptic strictures and 31 patients with esophageal cancer were evaluated with a two-phase dynamic contrast-enhanced MDCT. Arterial and venous phases at 10 and 35 s after the attenuation of 200 HU were obtained at the descending aorta, with a delayed phase at 6-8 min after the start of injection of contrast media. For qualitative analysis, CT scans of benign strictures were reviewed for the presence/absence of the following features: 'target sign', luminal mass, homogeneity of contrast medium uptake, concentric wall thickening, conically shapedsuprastenotic dilatation, smooth boundaries of stenosis and smooth mucous membrane at the transition to stenosis, which were compared with a control group of 31 patients who had esophageal cancer. The quantitative analysis included densitometric parameter acquisition using regions-of-interest measurement of the zone of stenosis and normal esophageal wall and the difference between those measurements(ΔCT) at all phases of bolus contrast enhancement. Esophageal wall thickening, length of esophageal wall thickening and size of the regional lymph nodes were also evaluated. RESULTS: The presence of a concentric esophageal wall, conically shaped suprastenotic dilatation, smooth upper and lower boundaries, 'target sign' and smooth mucous membrane at the transition to stenosis were suggestive of a benign cause, with sensitivities of 92.31%, 87.17%, 94.87%, 76.92% and 82.05%, respectively, and specificities of 70.96%, 89.66%, 80.65%, 96.77% and 93.55%, respectively. The features that were most suggestive of a malignant cause were eccentric esophageal wall thickening, tuberous upper and lower boundaries of stenosis, absence of mucous membrane visualization, rupture of the mucous membrane at the upper boundary of stenosis, cup-shaped suprastenotic dilatation, luminal mass and enlarged regional lymph nodes with specificities of 92.31% 94.87%, 67.86%, 100%, 97.44%, 94.87% and 82.86%, respectively and sensitivities of 70.97%, 80.65%, 96.77%, 80.65%, 54.84%, 87.10% and 60%, respectively. The highest tumor attenuation occurred in the arterial phase(mean attenuation 74.13 ± 17.42 HU), and the mean attenuation difference between the tumor and the normal esophageal wall(mean ΔCT) in the arterial phase was 23.86 ± 19.31 HU. Here, 11.5 HU of ΔCT in the arterial phase was the cut-off value used to differentiate esophageal cancer from post-inflammatory stricture(P = 0.000). The highest attenuation of postinflammatory strictures occurred in the delayed phase(mean attenuation 71.66 ± 14.28 HU), and the mean ΔCT in delayed phase was 34.03 ± 15.94 HU. Here, 18.5 HU of ΔCT in delayed phase was the cut-off value used to differentiate post-inflammatory stricture from esophageal cancer(P < 0.0001).CONCLUSION: The described imaging findings reveal high diagnostic significance in the differentiation of benign strictures from esophageal cancer. | Grigory G Karmazanovsky Svetlana A Buryakina Evgeny V Kondratiev Qin Yang Dmitry V Ruchkin Dmitry V Kalinin | 2015 | World Journal of Gastroenterology2015，21，29： | 3 |
| 4 | CHIP-ping away at tau显示文摘 | Dmitry G Ronald K H | 2007 | J Clin Invest2007，117，3： | 1 |
| 5 | Effect of hemagglutinin glycoprotein on influenza virus susceptibility to neuraminidase inhibitors 显示文摘 | Vasiliy P M Dmitri N Frederick G | 2005 | J Virol2005，79，12： | 1 |
| 6 | Effect of Two-and Three-locus linkage disequilibrium on the power to detect marker/phenotype associations显示文摘 | Dahila M N Margaret G E Dmitri V Z | 2004 | Genetics2004，168，： | 1 |
| 7 | Collagen coating promotes biocompatibility of semiconductor nanoparticles in stratified LBL films显示文摘 | Sinani Vladimir A Koktysh Dmitry S Yun B G | 2003 | Nano Lett2003，3，： | 1 |
| 8 | Photocatalytic activities of porous titania and titania/ zirconia structures formed by using a polymer gel templating technique显示文摘 | Jan H Dmitry S Shchukin G | 2002 | Chemistry Material2002，14，15： | 1 |
| 9 | Cerium phosphate nanotubes: synthesis, valence state, and optical properties显示文摘 | Tang C C Yoshio B Dmitri G | 2005 | Angewandte Chemie International Edition2005，44，57： | 1 |
| 10 | Influence of catalyst pretrentment ona-pinene isomerization over natural clays 显示文摘 | GONUL G DMITRY Y M | 2002 | React Kinet CatalLett2002，75，2： | 1 |
| 11 | The effect of rapid thermal processing (RTP) on TiN coatings deposited by PVD and the steel-turning performance of coated cemen- ted carbide 显示文摘 | Anthoy J Perry J N Steve J Bull Dmitri I P Peter C R Trevor F P Daniel E G James T John J V Robert E D Vladinmir R Alexey B M | 1999 | Surface and Coatings Technology1999，120，121： | 1 |
| 12 | Dynamics and temperature dependence of etching processes of porous and barrier aluminum oxide layers 显示文摘 | Dmitri A Brevnov Rama Rao G V Gabriel P Lrpez | 2004 | Electrochemical Acta2004，49，15： | 1 |
| 13 | Mecha- nisms of Flow Near Surface Electrical Discharge Genera- tion 显示文摘 | Leonov S B Dmitry A Y Gromov V G | 2006 | Vacuum2006，80，11： | 1 |
| 14 | Synthesis of nanosized magnetic ferrite particles inside hollow polyelectrolyte capsules显示文摘 | Dmitry G Shchukin Igor L Radtchenko Gleb B Sukhorukov | 2003 | J Phys Chem B2003，107，： | 1 |
| 15 | A simple model for solid polymer electrolyte (SPE) water electrolysis 显示文摘 | Pyoungho C Dmitri G B Ravindra D | 2004 | Solid State Ionics2004，175，14： | 1 |
| 16 | Detection and tracking of marine vehicles in video显示文摘 | SERGIY F DMITRY G | 2008 | IEEE2008，12，： | 1 |
| 17 | Correlation of emission capability and longevity of dispenser cathodes with characteristics of tungster powders 显示文摘 | lrina P M Victor G V Dmitry A U | 2003 | Applied Surface Science2003，215，： | 1 |
| 18 | Clinical significance of defective dendritic cell differentiation in cancer显示文摘 | Dmitry G Mayer F John S | 2000 | Clin Cancer Res2000，6，： | 1 |
| 19 | Photocatalytic activities of porous titania and titania/zirconia structures formed by using a polymer gel templating technique 显示文摘 | Jan H Schattka Dmitry G Shchukin Jianguang J | 2002 | Chem Mater2002，14，11： | 1 |
| 20 | Halloysite Clay Nanotubes for Controlled Release of Protective Agents 显示文摘 | Yuri M L Dmitry G Helmuth M Ronald R P | 2008 | Acs Nano2008，2，5： | 1 |
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