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| 1 | Role of polyethylene particles in peri-prosthetic osteolysis:A review显示文摘There is convincing evidence that particles produced by the wear of joint prostheses are causal in the periprosthetic loss of bone,or osteolysis,which,if it progresses,leads to the phenomenon of aseptic loosening.It is important to fully understand the biology of this bone loss because it threatens prosthesis survival,and loosened implants can result in peri-prosthetic fracture,which is disastrous for the patient and presents a difficult surgical scenario.The focus of this review is the bioactivity of polyethylene(PE)particles,since there is evidence that these are major players in the development and progression of osteolysis around prostheses which use PE as the bearing surface.The review describes the biological consequences of interaction of PE particles with macrophages,osteoclasts and cells of the osteoblast lineage,including osteocytes.It explores the possible cellular mechanisms of action of PE and seeks to use the findings to date to propose potential nonsurgical treatments for osteolysis.In particular,a nonsurgical approach is likely to be applicable to implants containing newer,highly cross-linked PEs(HXLPEs),for which osteolysis seems to occur with much reduced PE wear compared with conventional PEs.The caveat here is that we know little as yet about the bioactivity of HXLPE particles and addressing this constitutes our next challenge. | Gerald J Atkins David R Haynes Donald W Howie David M Findlay | 2011 | World Journal of Orthopedics2011，2，10： | 11 |
| 2 | T cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppression显示文摘 | Elena Klyushnenkova Joseph D Mosca Valentina Zernetkina Manas K Majumdar Kirstin J Beggs Donald W Simonetti Robert J Deans Kevin R McIntosh | 2005 | Journal of Biomedical Science2005，，1： | 2 |
| 3 | 2009年南极冰穹A的双色天光背景统计和分析显示文摘天光背景是天文台址的一个重要指标。利用2009年位于南极冰穹A的CSTAR望远镜两个波段的观测数据,对南极冰穹A的天光背景进行了统计和分析。结果表明约74%的g波段天光背景的ADU值小于每像素100/s;90.5%的r波段的天光背景的ADU值小于每像素100/s。在不考虑大气消光的情况下,定标后的结果为2009年冰穹A的观测数据中天光背景亮度的中值:g波段为19.9 mag/arcsec2,r波段为20.1 mag/arcsec2。 | 宗伟凯 付建宁 牛家树 Ashley Michael C B 宫雪非 Lawrence J S 刘强 Luong-Van Daniel Pennypacker C R Storey John W V 王灵芝 王力帆 杨惠根 袁祥岩 York Donald G 朱镇熹 | 2014 | 天文研究与技术2014，11，1： | 2 |
| 4 | No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics显示文摘 | Sanders Alan R Duan Jubao Levinson Douglas F Shi Jianxin He Deli Hou Cuiping Burrell Gregory J Rice John P Nertney Deborah A Olincy Ann Rozic Pablo Vinogradov Sophia Buccola Nancy G Mowry Bryan J Freedman Robert Amin Farooq Black Donald W | 2008 | The American Journal of Psychiatry2008，，4： | 1 |
| 5 | Cell cycle control as a basis for cancer drug development 显示文摘 | Mc Donald E R Deiry W S | 2000 | Int J Oncol2000，，16： | 1 |
| 6 | Sulfurcoated fertilizers for controlled release: pilot plant production 显示文摘 | Glenn M B Donald W R Oscar E M | 1971 | Agric Food Chem1971，19，5： | 1 |
| 7 | ELISA for the pyrethroid permethrin 显示文摘 | Guomin S Whiteey R Donald W | 2000 | J Agri Food Chem2000，48，9： | 1 |
| 8 | Electromagnetic scattering by surfaces of arbitrary shape 显示文摘 | Sadasiva M R Donald R W Allen W G | 1982 | IEEE Trans - AP1982，30，3： | 1 |
| 9 | Characterization and reactivity of iron nanoparticlesprepared with added Cu, Pd, and Ni显示文摘 | DONALD R B DEAN W M JAMES E A | 2010 | Environmen-tal Science and Technology2010，44，： | 1 |
| 10 | Adenosine inhibition of mcsopontinc cholincrgic neurons : implications for EEG arousal 显示文摘 | Donald G Rainnie Heinz C Grunze R W McCarley | 1994 | Science1994，263，5147： | 1 |
| 11 | Efficient operation of surface-mounted PM synchronous motors 显示文摘 | COLBY R S DONALD W N | 1987 | IEEE Transactions on Industry Applications1987，23，6： | 1 |
| 12 | Maximum likelihood estimation of K distribution paremeters for SAR data显示文摘 | Ian R J Donald B P Dale P W | 1993 | IEEE Transactions on Geoscience and Remote Sensing1993，31，5： | 1 |
| 13 | Is type 2 diabetes mellitus(NIDDM)a surgical disease?显示文摘 | Pories W J Mac Donald KG r Flickinger EG | 1992 | Ann Surg1992，215，： | 1 |
| 14 | The immobilization of high level radioactive wastes using ceramics and glasses显示文摘 | DONALD W METCALFE B L TAYLOR R N J | 1997 | Journal of Materials Science1997，32，22： | 1 |
| 15 | Efficient global optimization of expensive black-box functions显示文摘 | Donald R J Matthias S William J W | 1998 | Journal of Global Optimization1998，13，4： | 1 |
| 16 | Review: The immobilization of high level radioactive wastes using ceramics and glasses显示文摘 | DONALD I W METCALFE B L TAYLOR R N J | 1997 | J Mater Sci1997，，32： | 1 |
| 17 | Lehmann Customer Satisfaction, Market Share, and Profitability: Findings From Sweden显示文摘 | Eugene W Anderson Claes Fornell Donald R | 1994 | Journal of Marketing1994，，7： | 1 |
| 18 | Insecticidalcyclodepsipeptides frorn metarhizium anisopliae显示文摘 | Sandeep G Donald W R Renwick J A A | 1989 | Journalof the Chemical Society1989，，12： | 1 |
| 19 | An integrated SOFC plant dynamic model for power systems simulation显示文摘 | Padulles J Ault G W Mc Donald J R | 2000 | Journal of Power Sources2000，86，12： | 1 |
| 20 | Plant diversity,soil microbial communities,and ecosystem function:Are there any links显示文摘 | Donald R Z Willame H David C W | 2003 | Ecology2003，84，8： | 1 |
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