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| 1 | Lateral distributions of streamwise velocity in compound channels with partially vegetated floodplains显示文摘Natural rivers are commonly characterized by a main channel for primary flow conveyance and a floodplain, often partially covered with vegetation such as shrubs or trees, to carry extra flow during floods. The hydraulic resistance due to vegetation on the floodplain typically causes a further reduction of flow velocity and increases the velocity difference between the main channel and the floodplain. As a consequence a strong lateral shear layer leads to the exchange of mass and momentum between the main channel and floodplain, which in turn affects the overall channel conveyance and certain fluvial processes. The prediction of the lateral velocity distribution is important for many flood alleviation schemes, as well as for studies on sediment transport and dispersion in such channels. The present paper proposes a method for predicting the depth-averaged velocity in compound channels with partially vegetated floodplains, based on an analytical solution to the depth-integrated Reynolds-Averaged Navier-Stokes equation with a term included to account for the effects of vegetation. The vegetation is modelled via an additional term in the momentum equation to account for the additional drag force. The method includes the effects of bed friction, drag force, lateral turbulence and secondary flows, via four coefficients f, CD, λ & Γ respectively. The predicted lateral distributions of depth-averaged velocity agree well with the experimental data. The analytical solutions can also be used to predict the distribution of boundary shear stresses, which adds additional weight to the method proposed. | KNIGHT Donald W | 2009 | Science China(Technological Sciences)2009，52，11： | 13 |
| 2 | Role of polyethylene particles in peri-prosthetic osteolysis:A review显示文摘There is convincing evidence that particles produced by the wear of joint prostheses are causal in the periprosthetic loss of bone,or osteolysis,which,if it progresses,leads to the phenomenon of aseptic loosening.It is important to fully understand the biology of this bone loss because it threatens prosthesis survival,and loosened implants can result in peri-prosthetic fracture,which is disastrous for the patient and presents a difficult surgical scenario.The focus of this review is the bioactivity of polyethylene(PE)particles,since there is evidence that these are major players in the development and progression of osteolysis around prostheses which use PE as the bearing surface.The review describes the biological consequences of interaction of PE particles with macrophages,osteoclasts and cells of the osteoblast lineage,including osteocytes.It explores the possible cellular mechanisms of action of PE and seeks to use the findings to date to propose potential nonsurgical treatments for osteolysis.In particular,a nonsurgical approach is likely to be applicable to implants containing newer,highly cross-linked PEs(HXLPEs),for which osteolysis seems to occur with much reduced PE wear compared with conventional PEs.The caveat here is that we know little as yet about the bioactivity of HXLPE particles and addressing this constitutes our next challenge. | Gerald J Atkins David R Haynes Donald W Howie David M Findlay | 2011 | World Journal of Orthopedics2011，2，10： | 11 |
| 3 | Epigenetic profiles of pre-diabetes transitioning to type 2 diabetes and nephropathy显示文摘AIM: To examine DNA methylation profiles in a longitudinal comparison of pre-diabetes mellitus(Pre-DM) subjects who transitioned to type 2 diabetes mellitus(T2DM).METHODS: We performed DNA methylation study in bisulphite converted DNA from Pre-DM(n = 11) at baseline and at their transition to T2 DM using Illumina Infinium Human Methylation27 Bead Chip, that enables the query of 27578 individual cytosines at Cp G loci throughout the genome, which are focused on the promoter regions of 14495 genes.RESULTS: There were 694 Cp G sites hypomethylated and 174 Cp G sites hypermethylated in progression from Pre-DM to T2 DM, representing putative genes involved in glucose and fructose metabolism, inflammation, oxidative and mitochondrial stress, and fatty acid metabolism. These results suggest that this high throughput platform is able to identify hundreds of prospective Cp G sites associated with diverse genes that may reflect differences in Pre-DM compared with T2 DM. In addition, there were Cp G hypomethylation changes associated with a number of genes that may be associated with development of complications of diabetes, such as nephropathy. These hypomethylation changes were observed in all of the subjects.CONCLUSION: These data suggest that some epigenomic changes that may be involved in the progression of diabetes and/or the development of complications may be apparent at the Pre-DM state or during the transition to diabetes. Hypomethylation of a number of genes related to kidney function may be an early marker for developing diabetic nephropathy. | Thomas A Vander Jagt Monica H Neugebauer Marilee Morgan Donald W Bowden Vallabh O Shah | 2015 | World Journal of Diabetes2015，6，9： | 5 |
| 4 | Speakeasy: the military software radio显示文摘 | Raymond JL Donald W U | | 0，，： | 3 |
| 5 | Minimally invasive versus open oesophagectomy for patients with oesophageal cancer: a multicentre, open-label, randomised controlled trial显示文摘 | Surya SAY Biere Mark I van Berge Henegouwen Kirsten W Maas Luigi Bonavina Camiel Rosman Josep Roig Garcia Suzanne S Gisbertz Jean HG Klinkenbijl Markus W Hollmann Elly SM de Lange H Jaap Bonjer Donald L van der Peet Miguel A Cuesta | 2012 | The Lancet . 2012 (9829)2012，，： | 3 |
| 6 | The immobilization of high level radioactive wastes using ceramics and glasses显示文摘 | I. W Donald B. L Metcalfe R. N. J Taylor | 1997 | Journal of Materials Science1997，，22： | 2 |
| 7 | King, Lessons for the Futures of Journals显示文摘 | Carol Tenopir Donald W | 2001 | Nature2001，413，： | 2 |
| 8 | T cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppression显示文摘 | Elena Klyushnenkova Joseph D Mosca Valentina Zernetkina Manas K Majumdar Kirstin J Beggs Donald W Simonetti Robert J Deans Kevin R McIntosh | 2005 | Journal of Biomedical Science2005，，1： | 2 |
| 9 | 2009年南极冰穹A的双色天光背景统计和分析显示文摘天光背景是天文台址的一个重要指标。利用2009年位于南极冰穹A的CSTAR望远镜两个波段的观测数据,对南极冰穹A的天光背景进行了统计和分析。结果表明约74%的g波段天光背景的ADU值小于每像素100/s;90.5%的r波段的天光背景的ADU值小于每像素100/s。在不考虑大气消光的情况下,定标后的结果为2009年冰穹A的观测数据中天光背景亮度的中值:g波段为19.9 mag/arcsec2,r波段为20.1 mag/arcsec2。 | 宗伟凯 付建宁 牛家树 Ashley Michael C B 宫雪非 Lawrence J S 刘强 Luong-Van Daniel Pennypacker C R Storey John W V 王灵芝 王力帆 杨惠根 袁祥岩 York Donald G 朱镇熹 | 2014 | 天文研究与技术2014，11，1： | 2 |
| 10 | An efficient algorithm for analysis of nonlinear heat transfer with phase changes显示文摘 | Donald Rolph W Bathe K J | 1982 | International Journal for Numerical Methods in Engineering1982，18，： | 2 |
| 11 | Human ICE/CED-3 Protease Nomenclature显示文摘 | Emad S Alnemri David J Livingston Donald W Nicholson Guy Salvesen Nancy A Thornberry Winnie W Wong Junying Yuan | 1996 | Cell1996，，2： | 2 |
| 12 | Olympic games competition: structural correlates of national success显示文摘 | BALL DONALD W | 1972 | Int J Comparative Soc1972，12，： | 1 |
| 13 | Sequence analysis of ARI-1,a novel OXA beta-lactamase,responsible for imipenem resistance in Acinetobacter baumannii 6B92显示文摘 | Donald HM Scaife W Amyes SG | 2000 | Antimicrob Agents Chemother2000，，： | 1 |
| 14 | Management of intracranial dypertention显示文摘 | Donald W Peter BL | 1997 | Cotemporary Neurosurgery1997，19，1： | 1 |
| 15 | No Significant Association of 14 Candidate Genes With Schizophrenia in a Large European Ancestry Sample: Implications for Psychiatric Genetics显示文摘 | Sanders Alan R Duan Jubao Levinson Douglas F Shi Jianxin He Deli Hou Cuiping Burrell Gregory J Rice John P Nertney Deborah A Olincy Ann Rozic Pablo Vinogradov Sophia Buccola Nancy G Mowry Bryan J Freedman Robert Amin Farooq Black Donald W | 2008 | The American Journal of Psychiatry2008，，4： | 1 |
| 16 | Harmonic diffractive lenses 显示文摘 | DONALD W S GARY E S | 1995 | Appl Opt1995，34，： | 1 |
| 17 | Perspectives in alkline phosphatase research显示文摘 | DONALD W M | 1992 | Clin Chem1992，38，12： | 1 |
| 18 | Sequence analysis of ARI-1, a novel OXA beta-lactamase, responsible for imipenem resistance in Acinetobacter baumannii 6B92显示文摘 | Donald HM Scaife W Amyes SG | 2000 | Antimicrob Agents Chemother2000，44，： | 1 |
| 19 | Magnetorheological finishing in commercial precision optics manufacturing显示文摘 | Golini D Donald Kordonski W I | 1999 | SPIE1999，3782，： | 1 |
| 20 | Design considerations and topology selection for 120 kW IGBT converter for EV fast charging显示文摘 | Nasser H Kutkut Deepak M Divan Donald W Novotny | 1998 | IEEE Transactions on Power Electronics1998，13，1： | 1 |
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