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| 1 | Helicobacter pylori recurrence after eradication in Latin America:Implications for gastric cancer prevention显示文摘AIM To estimate Helicobacter pylori(H. pylori) recurrence rate in Latin America, a region with a significant H. pylori prevalence and gastric cancer burden.METHODS Pub Med, LILACS, Sci ELO, Cochrane databases and abstracts from relevant meetings were reviewed. Information collected included: Participants' characteristics, recruitment strategy, diagnostic modality, treatment arms, follow-up and recurrence rates. Recurrence was calculated using 100-patients-year rates, and data were pooled using a random effects model. The I2 statistic assessed between study heterogeneity. Meta-regression analyses evaluated for effect modifying variables. RESULTS Literature search yielded 163 articles. Twelve studies involving 4848 patients from 9 countries met inclusion criteria. Four hundred and thirty-two reinfections were recorded in 5487 person-years of follow-up. Pooled analysis showed a recurrence rate of 7.9 cases per 100 person-years(95%CI: 5.3-10.5). Meta-regression revealed that neither the antibiotic schema, a second antibiotic course, nor the diagnostic modality had an impact on the observed risk of recurrence. The recurrence rate in the first year after treatment, predominantly recrudescence,was 11.2(6.1-16.4) per 100 patient years. Recurrence in subsequent years, was only 6.2(3.8-8.7).CONCLUSION H. pylori recurrence rates in Latin America are significant, and with geographic variability, yet are acceptable based upon the current literature for consideration of large scale intervention trials. Further research in Latin America is warranted to evaluate the efficacy, cost-effectiveness, and potential adverse outcomes of proposed eradication programs. | Juan E Corral Robertino Mera Corey W Dye Douglas R Morgan | 2017 | World Journal of Gastrointestinal Oncology2017，9，4： | 5 |
| 2 | 14-day triple, 5-day concomitant, and 10-day sequential therapies for Helicobacter pylori infection in seven Latin American sites: a randomised trial显示文摘 | E Robert Greenberg Garnet L Anderson Douglas R Morgan Javier Torres William D Chey Luis Eduardo Bravo Ricardo L Dominguez Catterina Ferreccio Rolando Herrero Eduardo C Lazcano-Ponce María Mercedes Meza-Montenegro Rodolfo Pe?a Edgar M Pe?a Eduardo Salazar- | 2011 | The Lancet2011，，9790： | 2 |
| 3 | Difference in dietary intake between women with polycystic ovary syndrome and healthy controls 显示文摘 | Douglas C C Norris L E Oster R A | 2006 | Fertil Steril2006，86，2： | 1 |
| 4 | Environmentalstability of selected petroleum hydrocarbon source and weatheringratios显示文摘 | Douglas G S Bence A E Prince R C | 1996 | Environmental Science&Technology1996，30，7： | 1 |
| 5 | Mixed-genome microarrays reveal multiple serotype and LineageSpecific Differences among Strains of Listeria monocytogene 显示文摘 | DOUGLAS R CALL MONICA K BORUCKI THOMAS E BESSER | 2003 | J Clin Microbiol2003，41，2： | 1 |
| 6 | An introduction to DNA microarrays for gene expression analysis显示文摘 | Karakach T K Flight R M Douglas S E | 2010 | Chemometrics Intell Lab Syst2010，104，1： | 1 |
| 7 | Emotion Recognition in Human -computer Interaction 显示文摘 | Cowie R Douglas - Cowie E | 2001 | IEEE Signal Processing Magazine2001，18，1： | 1 |
| 8 | Geotextile tubes as submerged dykes for shoreline management in Malaysia显示文摘 | LEE E C DOUGLAS R S | 2012 | Geotextiles and Geomembranes2012，30，： | 1 |
| 9 | Fecal calprotectin levels predict colorectal inflammation among patients with chronic diarrhea referred for colonoscopy显示文摘 | Paul J Limburg David A Ahlquist William J Sandborn Douglas W Mahoney Mary E Devens Jonathan J Harrington Alan R Zinsmeister | 2000 | The American Journal of Gastroenterology2000，，10： | 1 |
| 10 | Passive thermal energy storage in refrigerated warehouse显示文摘 | Altwies Douglas T R | 2001 | International Journal of Refrigeration2001，，24： | 1 |
| 11 | Identification and expression analysis of hepcidin-like antimicrobial peptides in bony fish显示文摘 | Douglas S E Gallant J W Liebscher R S | 2003 | Dev Comp Immunol2003，27，： | 1 |
| 12 | The approximation of the pressure by a mixed method in the simulation of miscible displacement显示文摘 | J Douglas Jr R E Ewing M F Wheeler | 1983 | RAIRO Numer Anal1983，17，： | 1 |
| 13 | Color match of machinable lithium disillcate ceramics:Effects of cement color and thickness显示文摘 | Niu E Agustin M Douglas R D | 2014 | The Journal of prosthetic dentistry2014，111，1： | 1 |
| 14 | Trends in floods and low flows in the United States: impact of spatial correlation 显示文摘 | Douglas E M Vogel R M Kroll C N | 2000 | Journal of Hydrology2000，，240： | 1 |
| 15 | Design and performance of Sandia's contactless coilgun for 50 mm projectiles显示文摘 | Kaye R J Conare E C Douglas M C | 1995 | IEEE Transac- tions on Magnetics1995，29，1： | 1 |
| 16 | Global estimates for mixed methods for second order elliptic equations显示文摘 | Douglas JJ r Roberts J E | 1985 | Math Comp1985，44，： | 1 |
| 17 | The products of human cytomegalovirus genes UL23, UL24, UIA-3 and US22 are tegument components显示文摘 | Adair R Douglas E R Maclean J B | 2002 | J Gen Virol2002，83，6： | 1 |
| 18 | Trends in floods and low flows in the United States:impact of spatial correlation显示文摘 | Vogel R M Kroll C N | 2000 | Journal of Hydrology2000，，240： | 1 |
| 19 | Supply Chain Management:More than a New Name for Logistics显示文摘 | Cooper M C Douglas M Lambert R E Mason Janus D Pagh | 1997 | International Journal of Logistics Management1997，8，1： | 1 |
| 20 | Identification andexpression analysis of hepcidin-like antimicrobial peptides inbony fish显示文摘 | Douglas S E Gallant J W Liebscher R S | 2003 | Developmental and Comparative Immunology2003，27，67： | 1 |
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