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| 1 | Agricultural Risk Factors Influence Microbial Ecology in Honghu Lake显示文摘Agricultural activities, including stock-farming, planting industry, and fish aquaculture,can affect the physicochemical and biological characters of freshwater lakes. However, the effects of pollution producing by agricultural activities on microbial ecosystem of lakes remain unclear.Hence, in this work, we selected Honghu Lake as a typical lake that is influenced by agriculture activities. We collected water and sediment samples from 18 sites, which span a wide range of areas from impacted and less-impacted areas. We performed a geospatial analysis on the composition of microbial communities associated with physicochemical properties and antibiotic pollution of samples. The co-occurrence networks of water and sediment were also built and analyzed. Our results showed that the microbial communities of impacted and less-impacted samples of water were largely driven by the concentrations of TN, TP, NO_3^--N, and NO_2^--N, while those of sediment were affected by the concentrations of Sed-OM and Sed-TN. Antibiotics have also played important roles in shaping these microbial communities: the concentrations of oxytetracycline and tetracycline clearly reflected the variance in taxonomic diversity and predicted functional diversity between impacted and less-impacted sites in water and sediment samples, respectively. Furthermore, for samples from both water and sediment, large differences of network topology structures between impacted and less-impacted were also observed. Our results provide compelling evidence that the microbial community can be used as a sentinel of eutrophication and antibiotics pollution risk associated with agricultural activity; and that proper monitoring of this environment is vital to maintain a sustainable environment in Honghu Lake. | Maozhen Han Melissa Dsouza Chunyu Zhou Hongjun Li Junqian Zhang Chaoyun Chen Qi Yao Chaofang Zhong Hao Zhou Jack A Gilbert Zhi Wang Kang Ning | 2019 | Genomics, Proteomics & Bioinformatics2019，17，1： | 3 |
| 2 | Surface and subsurface characterization of epoxy - mesoporous silica composites to clarify tribological properties显示文摘 | M C Romanes N A DSouza D Coutinho | 2008 | Wear2008，265，12： | 1 |
| 3 | Supramolecular tandem en-zyme assays显示文摘 | Dsouza R N Hennig A Nau W M | 2012 | Chem Eur J2012，18，12： | 1 |
| 4 | Immunization with 60-kD Ro peptide produces different stages of preclinical autoimmunity in a Sj(o)gren's syndrome model among multiple strains of inbred mice显示文摘 | Kurien BT Dsouza A Igoe A | 2013 | Clin Exp Immunol2013，173，： | 1 |
| 5 | Multiplex Nucleic Acid Sequence-Based Amplification for Simultaneous Detection of Several Enteric Viruses in Model Ready-To-Eat Foods 显示文摘 | JEAN J DSOUZA D H JAYKUS L A | 2004 | Appl Environ Microbiol2004，70，11： | 1 |
| 6 | Modification of cement mortar with recycled ABS显示文摘 | PALOS A DSOUZA N A SNIVELY C T | 2001 | Cement and Concrete Research2001，31，7： | 1 |
| 7 | Isolation of laccase gene-specific sequences from white rot and brown rot fungi by PCR显示文摘 | DSOUZA T M BOOMINATHAN K REDDY C A | 1996 | Applied and Environmental Microbiology1996，62，10： | 1 |
| 8 | Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome显示文摘 | Carvajal-Vergara X Sevilla A DSouza SL | 2010 | Nature2010，465，7299： | 1 |
| 9 | Interactions among friction, wear, and system stiffness-part 2 : vibrations induced by dry friction 显示文摘 | ARONOV V DSOUZA A F KALPAKJIAN S | 1984 | J of Trib1984，106，： | 1 |
| 10 | The many facets of Notch lig ands 显示文摘 | Dsouza B Miyamoto A Weinmaster G | 2008 | Oncogene2008，27，38： | 1 |
| 11 | Enhanced production of laccase by a marine fungus during treatment of colored effluents and synthetic dyes显示文摘 | DSouza D T Tiwari R Sah A K | 2006 | Enzyme and Microbial Technology2006，38，： | 1 |
| 12 | Lacosamide: pharmacology, mechanisms of action and pooled efficacy and safety data in partial-onset seizures显示文摘 | Beydoun A DSouza J Hebert D | 2009 | Expert Rev Neurother2009，9，1： | 1 |
| 13 | Damage evaluation of offshore structures using resonant frequency shifts显示文摘 | Dsouza P D Qiang Y | 1992 | Serviceability of Petroleum Process and Power Equipment1992，239，33： | 1 |
| 14 | Isolation of a starch utilizing,phosphate solubilizing fungus on buffered medium and its characterization 显示文摘 | AHUJA A GHOSH S B DSOUZA S F | 2007 | Bioresource Technology2007，98，17： | 1 |
| 15 | The utility of plasma vascular endothelial growth factor levels in the di- agnosis and follow-up of patients with POEMS syndrome 显示文摘 | DSouza A Hayman S R Buadi F | 2011 | Blood2011，118，17： | 1 |
| 16 | Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting 显示文摘 | Tanghe A DSouza S Rosseels V | 2001 | Infect Immun2001，69，5： | 1 |
| 17 | The many facets of Notch ligands显示文摘 | DSOUZA B MIYAMOTO A WEINMASTER G | 2008 | Oncogene2008，27，38： | 1 |
| 18 | Rational development of neuraminidase inhibitor as novel anti-flu drug 显示文摘 | Chintakrindi A Dsouza C Kanyalkar M | 2012 | Mini Rev Med Chem2012，12，12： | 1 |
| 19 | Selected ehemo-ecologieal studies of marine ophisthobranehs from Indian coast显示文摘 | FONTANA A CIAVATA M L DSOUZA L | 2001 | J Indian Inst Sci2001，81，： | 1 |
| 20 | Meat flavor volatiles: a review of the composition, techniques of analysis and sensory evaluation 显示文摘 | Shahidi F Rubin L J DSouza L A | 1986 | Crit Hey Food Sci Nutr1986，24，2： | 1 |
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