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| 1 | Comparative Proteome Analysis of Human Lung Squamous Carcinoma Tissue显示文摘客观:与高分辨率建立二维的电气泳动侧面;从人的肺的重制度有鳞的癌织物;配对的正常肿瘤邻近的支气管的上皮,;识别微分表示由使用 proteome 分析的联系肿瘤的蛋白质。方法:有 20 人的肺的比较 proteome 分析有鳞的癌纸巾;邻近肿瘤的配对的正常支气管的上皮被执行。人的肺的全部的蛋白质有鳞的癌织物;配对的正常肿瘤邻近的支气管的上皮借助于使不能调动的 pH 被分开基于坡度的二维的胶化电气泳动(2-DE ) ;染色的银。微分表示蛋白质被分析;然后到飞行团分光术(MALDI-TOF-MS ) 的帮助矩阵的激光解吸附作用 / 电离时间识别了。结果:(1 ) 人的肺的解决得好的、可再现的 2-DE 模式有鳞的癌;邻近的正常支气管的上皮被获得。为肿瘤织物, 3 胶化的平均的点是 1567 ± 4 6,;4 看到的 1436 ± 5 与 91.6% 的平均匹配率被匹配。为控制, 3 胶化的平均的点是 1349 ± 5 8,;5 看到的 1228 ± 3 与 91.03% 的平均匹配率被匹配。匹配的点的平均位置偏差是在 IEF 的 0.924 ± 0 .128 公里方向,;在 SDS 页方向的 1.022 ± 0 .205 公里;(2 ) 6 看到的 1178 ± 5 的一个总数在 20 人的肺的电泳地图之间被匹配有鳞的癌纸巾;配对正常肿瘤邻近的支气管的上皮。76 差别表示了蛋白质被屏蔽;(3 ) 68 微分蛋白质被 PMF 识别,一些蛋白质是 oncogenes 的产品,;涉及房间的规定的其它骑车;信号转导变异;(4 ) 以便验证识别结果的可靠性, 3 蛋白质 mdm2 的表示, c-jun;EGFR,它与肺被相关有鳞的癌,被免疫检测组织化学的染色;西方的污点分析。结果揭示了那 mdm2, c-jun;EGFR 在肺是起来调整的有鳞的癌而他们在邻近的正常支气管的上皮是下面调整的,正常的肺纸巾;煽动性的假肿瘤,它与我们的 proteome 分析一致结果。结论:人的肺的解决得好的、可再现的 2-DE 模式有鳞的癌;邻近的正常支气管的上皮被建立;68 微分蛋白质被成功地使用比较 proteome 分析描绘。这些结果将为屏蔽使用到 diagnose 的分子的简历标记提供科学基础;对待肺有鳞的癌,以及改进病人的预后;为肺的研究提供新线索有鳞的致癌机制。 | LI Cui TANG Can'e DUAN Chaojun YI Hong XIAO Zhiqiang CHEN Zhuchu | 2006 | The Chinese-German Journal of Clinical Oncology2006，5，4： | 11 |
| 2 | Reflections on the Catastrophic 2020 Yangtze River Basin Flooding in Southern China显示文摘During the summer of 2020,southern China suffered from catastrophic flooding,the massive basin flood mainly occurred in the Yangtze River's middle and lower reaches.As of July 20,2020,the cumulative precipitation since the rain season started exceeded 500 mm over most of the Yangtze River Basin,reaching>1,200 mm in some areas of the lower reaches,exceeding the same period in 1998,the severest flood year in the past 60 years.Several water gauge stations at Poyang Lake and Chaohu Lake exceeded their historical record values.The water levels in the Wuhan section of the Yangtze River were among the highest ever recorded.As of July 22,2020,45.5 million people had been affected by the floods,with 142 people having died or were missing,and the direct economic losses expected to be around 116 billion RMB(~16.5 billion US dollars).However,the losses from this flood are much lower than those of previous major floods.For example,the catastrophic 1998 flooding led to 1,526 deaths and economic losses of 255 billion RMB(~36.4 billion US dollars).The reasons behind this are worthy of further study and discussion,and may be used for reference in the future and for other countries. | Ke Wei Chaojun Ouyang Hongtao Duan Yunliang Li Mingxing Chen Jiao Ma Huicong An Shu Zhou | 2020 | The Innovation2020，1，2： | 2 |
| 3 | The Disillusionment of the National Ideal Image of China During the Reign of the Qing Dynasty显示文摘The author analyzed the subjective factors of the gradual disillusionment of China’s national image, which can be summed up as the increasingly conservative ruling policy of the Qing Dynasty, the increasingly extravagant and corrupt feudal ruling groups, the increasing diplomatic strategy of seclusion and the increasingly imprisoned ruling ideology. The root cause lay in the decline of agricultural civilization and the rise of industrial civilization. The seclusion of the Qing Dynasty caused China to miss the wave of industrial civilization development, and finally led to the reversal of the image of the West and China. | DUAN Feng LI Chaojun | 2019 | Journal of Landscape Research2019，11，6： | 0 |
| 4 | The Decline of Image of China Under the Background of Rites Controversy in Qing Dynasty显示文摘At the turn of the 18th-19th century,in the process of developing missionary business in China,there was a debate about the nature of traditional Chinese sacrificial rites among missionaries,that is,whether the traditional rites of Confucius and Christianity were consistent.With the intervention of the Vatican and the Qing Dynasty,the Chinese rites controversy evolved into the dispute over Chinese imperial power and Roman religious imperial power.The missionary career in China also experienced the transformation from the toleration order,exclusion order and the ticket receiving order to the prohibition order.The sharp opposition between Chinese imperial power and Roman religious imperial power led to the desperate situation of Christian career in China.The missionaries naturally vented their dissatisfaction with China,the good image of China gradually collapsed,and the western image of China began to decline rapidly. | DUAN Feng LI Chaojun | 2020 | Journal of Landscape Research2020，12，1： | 0 |
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