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181篇 您的检索式:作者名="DUDA P"
    题名 作者 年代 出处 被引量
1A nuclear import inhibitory peptide ameliorates the severity of cholecystokinin-induced acute pancreatitis显示文摘AIM: To assess the effect of our novel cell-permeable nuclear factor-kappaB (NF-κB) inhibitor peptide PN50 in an experimental model of acute pancreatitis. PN50 was produced by conjugating the cell-penetrating penetratin peptide with the nuclear localization signal of the NF-κB p50 subunit.METHODS: Pancreatitis was induced in male Wistar rats by administering 2×100 μg/kg body weight of cholecystokininoctapeptide (CCK) intraperitoneally (IP) at an interval of 1 h. PN50-treated animals received 1 mg/kg of PN50 IP 30 min before or after the CCK injections. The animals were sacrificed 4 h after the first injection of CCK.RESULTS: All the examined laboratory (the pancreatic weight/body weight ratio, serum amylase activity,pancreatic levels of TNF-α and IL-6, degree of lipid peroxidation, reduced glutathione levels, NF-κB binding activity, pancreatic and lung myeloperoxidase activity) and morphological parameters of the disease were improved before and after treatment with the PN50 peptide.According to the histological findings, PN50 protected the animals against acute pancreatitis by favoring the induction of apoptotic, as opposed to necrotic acinar cell death associated with severe acute pancreatitis.CONCLUSION: Our study implies that reversible inhibitors of stress-responsive transcription factors like NF-κB might be clinically useful for the suppression of the severity of acute pancreatitis.Tamás Letoha Csaba Somlai Tamáas Takács Annamária Szabolcs Katalin Jármay Zoltán Rakonczay Jr Péter Hegyi Ilona Varga József Kaszaki István Krizbai Imre Boros Ern(?) Duda Erzsébet Kusz Botond Penke 2005World Journal of Gastroenterology2005,11,7:15
2Adaptation of HIV-1to human leukocyte antigen class I显示文摘Kawashima Y Pfafferott K Frater J Matthews P Payne R Addo M Gatanaga H Fujiwara M Hachiya A Koizumi H Kuse N Oka S Duda A Prendergast A Crawford H Leslie A Brumme Z Brumme C Allen T Brander C Kaslow R Tang J Hunter E Allen S Mulenga J Branch S Roach T John M Mallal S Ogwu A Shapiro R Prado J G Fidler S Weber J Pybus O G Klenerman P Ndung'u T Phillips R Heckerman D Harrigan P R Walker B D Takiguchi M Goulder P 2009Nature2009,458,7238:1
3Mesenchymal stem cell therapy following muscle trauma leads to im- proved muscular regeneration in both male and female rats 显示文摘von Roth P Duda GN Radojewski P 2012Gend Med2012,9,2:1
4Use of the Hough transform to detect lines and curves in pictures显示文摘Duda R O Hart P E 1972Communications of the ACM1972,15,1:1
5Quantum Dots Spectrally Distinguish Multiple Species within the Tumor Milieu in Vivo显示文摘Stroh M Zimmer J P Duda D G 2005NatureMedicine2005,11,:1
6Quantum dots spectrally distinguish multiple species with the tumor milieu in vivo显示文摘Stroh M Zimmer J P Duda D G 2005Nat Med2005,11,6:1
7Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells显示文摘Duda D G Sunamura M Lefter L P 2003Oncogene2003,22,44:1
8Use of the Hough transformation to detect lines and curves in pictures显示文摘Duda R O Hart P E 1972Communication of the ACM1972,15,1:1
9Use of the Hough transformation to detect lines and curves in pictures 显示文摘DUDA R O HART P E 1972Communications of the ACM1972,15,1:1
10Use of the Hough transformation to detect lines and curves in pictures显示文摘Duda R O Hart P E 1972Communications of the ACM1972,15,1:1
11Use of the Hough transformation to detect lines and curves in pictures显示文摘DUDA R O HART P E 1972Communications of the ACM1972,15,1:1
12Pattern Classification显示文摘DUDA R O HART P E STORK D G 2007Journal of Classification2007,2,24:1
13Use of the hough transformation to detect lines and curves in pictures显示文摘Duda R O Hart P E 1972Communications of the Asso- ciation for Computing Machinery1972,,15:1
14Use of the Hough transformation to detect lines and curves in pictures显示文摘Duda R O Hart P E 1971Artificial Intelligence Center1971,,:1
15Guidelines on use of anti-IFN-beta antibody measurements in multiple sclerosis:report of an EFNS Task Force on IFN-beta antibodies in multiple sclerosis显示文摘SORENSEN PS DEISENHAMMER F DUDA P 2005Eur J Neurol2005,12,11:1
16Use of Hough transformation to detect lines and curves in pictures显示文摘DUDA R O HART P E 1972Commun ACM1972,18,2:1
17Pattern classification and scene analysis显示文摘Duda R O Hart P E 1973Toronto: John Wiley and Sons1973,,:1
18Roles of diversifying selection and coordinated evolution in the evolution in the evolution of amphibian antimicrobial peptides显示文摘Duda T F Jr Vanhoye D Nicolas P 0,,:1
19Pattern classification and scene analysis显示文摘Duda R Hart P 19731973,,:1
20Diffusion and equilibriumts in ternary polymer- solvent - solvent systems using inverse gas chromatography 显示文摘Surana R K Danner R P Duda J L 1998Ind Eng Chem Res1998,37,:1
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