|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition显示文摘在人的不孕病人的精子在场的最普通的损害之一是精子鸡蛋识别的自发的失败。尽管这个唯一的细胞的相互作用现在能被象 intracytoplasmic 精子注射(ICSI ) 那样的帮助繁殖策略乐意地绕过,最近的大规模流行病学的研究鼓励了这种技术的小心的使用并且为对为有缺点的精子鸡蛋识别负责的机制的进一步的研究加亮需要。这个领域里的以前的工作证实了为卵母细胞相互作用负责的精子领域在动态地在女繁殖的道在 epididymal 成熟和 capacitation 期间被修改以前在精子发生期间被形成。当为这些顺序的 maturational 事件的规定负责的因素无疑是复杂的时,新兴的研究识别了分子的女伴,加热吃惊蛋白质 A2 (HSPA2 ) ,,在人的精子的这些事件的一个关键管理者。HSPA2 是支持合拢,运输,和集会蛋白质建筑群的 70 kDa 热吃惊蛋白质家庭的一个充实睾丸的成员并且断然被相关与在 vitro 授精(IVF ) 成功。而且,从人的精子 proteome 减少了 HSPA2 的表示为跟随 IVF 和 ICSI 的积云矩阵疏开,精子鸡蛋识别和授精导致一个损害能力。在这评论,我们考虑在精子功能支持 HSPA2 的角色的证据并且探索它被在不肥沃的病人的精子弄空的潜在的机制。进管理精子的分子的机制的如此的信息提议小说卓见工作。 | Brett Nixon Elizabeth G Bromfield Matthew D Dun Kate A Redgrove Eileen A McLaughlin R John Aitken | 2015 | Asian Journal of Andrology2015，17，4： | 8 |
| 2 | Bay of island and Little Port complexes, revisited: Age, geochemical and isotopic evidence confirm supra-subduction zone origin显示文摘 | JNNER G A DUNNING G R MALAPS J | 1991 | Can J Geol Soc London1991，28，： | 1 |
| 3 | Melatonin and stable circadian rhythms optimize maternal, placental and fetal physiology 显示文摘 | Reiter R J Dun XT Korkmaz A | 2014 | Hum Reprod Update2014，20，2： | 1 |
| 4 | Lack of evidence for an association between alpha-adducin and blood pressure regulation in Asian populalions显示文摘 | Koustubh R Agnes C H Kwan Dun W | 2000 | Am J Hypertens2000，13，70： | 1 |
| 5 | U-Pb geochronology and origin of granitoid rocks in Thetford Mine ophiolite, Canadian Appalachians显示文摘 | WHITEHEAD J SPRAY J G DUNNING G R | 2000 | Geological Society of America Bulletin2000，112，6： | 1 |
| 6 | Some in vivo effects of localized nuclear disintegration products on a transplantable mouse sarcoma显示文摘 | ZAHL P A COOPER F S DUNNING J R | 1940 | Ptoc Natl Acad Sci1940，26，： | 1 |
| 7 | The application of laser-ablationmicroprobe; inductively coupled plasma-mass spectrometry (LAM-ICP-MS) to in situtrace-element determinations in minerals显示文摘 | JACKSON S E LONGERICH H P DUNNING G R | 1992 | The Canadian Mineralogist1992，304，： | 1 |
| 8 | Mechanisms of plasma -enhanced silicon nitride deposition using SiH4/N2 mixture显示文摘 | Dun H Pan P White F R | 1981 | J Electrochem Soc1981，128，7： | 1 |
| 9 | The appli- cation of laser-ablation microprobe~ inductively coupled plas- ma-mass spectrometry (LAM ICP MS) to in situ trace-element determinations in minerals显示文摘 | Jackson S E Longerich H P Dunning G R | 1992 | Can Mineral1992，30，4： | 1 |
| 10 | Upper cervical and upper thoracic manipulation versus mobilization and exercise in patients with cervicogenic headache:a multi - center randomized clinical trial 显示文摘 | Dunning JR Butts R Mourad F | 2016 | BMC Musculoskelet Disord2016，17，1： | 1 |
| 11 | Loss of SOX10 function contributes to the phenotype of human Merlin-null schwannoma cells显示文摘 | DODDRELL R D DUN X P SHIVANE A | 2013 | Brain2013，136，2： | 1 |
| 12 | Dendrimer-platinate:a novel approach to cancer chemotherapy 显示文摘 | Evagorous E G Dun C R | 1999 | Anticancer Drug Des1999，10，8： | 1 |
| 13 | The effect of leg length discrepancy on pelvis and spine kinematics during gait显示文摘 | Needham R Chockalingam N Dunning D | 2012 | Stud Health Technol Inform2012，176，： | 1 |
| 14 | High-fat diet causeslipotoxicity responses in cumulus-oocyte complexes and decreasedfertilization rates 显示文摘 | WU L L Dunning K R YANG X | 2010 | Endocrinology2010，151，11： | 1 |
| 15 | Prevalence and clinical consequences of herpes simplex virus type 1 FINA in human cornea tissues显示文摘 | Remeiier L Duan R van Dun JM | 2009 | Infect Dis2009，200，1： | 1 |
| 16 | Dendrimer platiante a novel approach to cancer chemotherapy显示文摘 | Malik N R Evagorous E G Dun C R | | 0，，08： | 1 |
| 17 | Graduate nurse's communication with health professionals when managing patients medications显示文摘 | MANIAS E AITKEN R DUNNING T | 2005 | J Clin Nurs2005，14，3： | 1 |
| 18 | Rapid formation of a supramolecular polypeptide-DNA hydrogel for in situ three-dimensional multilayer bioprinting显示文摘 | LI C FAULKNER-JONES A DUN A R JIN J CHEN P X1NG Y YANG Z LI Z SHU W LIU D DUNCAN R R | 2015 | Angewandte Chemie International Edition2015，54，： | 1 |
| 19 | Melatonin in walnuts: influence on levels of melatonin and total antioxidant capacity of blood显示文摘 | Reiter R J Manchester L C Dun X T | 2005 | Nutrition2005，21，9： | 1 |
| 20 | Bay of Island and Little Port complexes,revisited:age,geochemical and isotopic evidence confirm suprasubduction-zone origin显示文摘 | Jenner G A Dunning G R Malpas J | 1991 | Canadian Journal of Earth Sciences1991，28，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员