维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

17篇 您的检索式：作者名="DaiCS"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	Effect of boundary on the onset of Rayleigh-Benard convection in a horizontal PCM slurry layer 显示文摘	DaiC YangLB LiW	2008	Journal of Enhanced Heat Transfer2008，15，1：	1
	2	查看详情显示文摘	DaiC M Zhou X F Zhang Y L		0，，：	1
	3	Low ultrasonic stimulates fermentation of riboflavin producing strain Ecemothecium ashbyii 显示文摘	DaiC Wang B Duan C	2003	Colloid Surf B Biointerfaces2003，30，：	1
	4	Surface segregationstudies of fluorine-containing diblock copolymers显示文摘	LYENGAR D R PERUTZ S M DAIC A	1996	Macromolecu-les1996，29，4：	1
	5	Monocyte chemo attractant protein-1 expression in renal tissue is associated with monocyte recruitment and tubulointerstitial lesions inpatients with lupus nephritis显示文摘	DaiC LiuZ zhou H	2001	Chin Med J (Engl)2001，114，：	1
	6	Triptolide inhibits proinflammmatory factor-induced over-expression of class Ⅱ MHC and B7 molecules in renaltubular epithelial cells显示文摘	Li H Liu ZH DaiCS		0，，09：	1
	7	PINCH - 1 promotes tubular epithelial - to - mesenchymaltr - ansitionby interacting with integrinlinked kinase 显示文摘	Ji Y DaiC WuC	2007	J Am Soc Nephrol2007，18，：	1
	8	显示文摘	DaiC L Mao C L Fu SC	2007	Sens Actuat B2007，123，2：	1
	9	Expression of insect (Microdera puntipennis dzungarica) antifreeze protein MpAFP149 confers the cold tolerance to transgenic tobacco显示文摘	WangY Qiu L DaiC		0，，08：	1
	10	A novelmechanism by which hepatocyte growth factor blocks tubular epithelial to mesenchymal transition显示文摘	Yang JW DaiCS Liu YH	2005	JAm SocNephrol2005，16，：	1
	11	Inhibition of PI3K/AKT/mTOR pathway enhances temozolomide-induced cytotoxicity in pituitary adenoma cell lines in vitro and xenografted pituitary adenoma in female nude mice 显示文摘	DaiC ZhangB LiuX	2013	Endocrinology2013，154，12：	1
	12	Anticarin-β shows a promising antiosteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis显示文摘Unlike healthy, non-transformed cells, the proteostasis network of cancer cells is taxed to produce proteins involved in tumor development. Cancer cells have a higher dependency on molecular chaperones to maintain proteostasis. The chaperonin T-complex protein ring complex(TRiC) contains eight paralogous subunits(CCT1-8), and assists the folding of as many as 10% of cytosolic proteome.TRiC is essential for the progression of some cancers, but the roles of TRiC subunits in osteosarcoma remain to be explored. Here, we show that CCT4/TRiC is significantly correlated in human osteosarcoma,and plays a critical role in osteosarcoma cell survival. We identify a compound anticarin-β that can specifically bind to and inhibit CCT4. Anticarin-β shows higher selectivity in cancer cells than in normal cells. Mechanistically, anticarin-β potently impedes CCT4-mediated STAT3 maturation. Anticarin-β displays remarkable antitumor efficacy in orthotopic and patient-derived xenograft models of osteosarcoma.Collectively, our data uncover a key role of CCT4 in osteosarcoma, and propose a promising treatment strategy for osteosarcoma by disrupting CCT4 and proteostasis.	Gan Wang Min Zhang Ping Meng Chengbo Long Xiaodong Luo Xingwei Yang Yunfei Wang Zhiye Zhang James Mwangi Peter Muiruri Kamau Zhi Daic Zunfu Ke Yi Zhang Wenlin Chen Xudong Zhao Fei Ge Qiumin Lv Mingqiang Rong Dongsheng Li Yang Jin Xia Sheng Ren Lai	2022	Acta Pharmaceutica Sinica B2022，12，5：	1
	13	Acoustic emission analysis on tensile failure of air plasma-sprayed thermal barrier coatings显示文摘	YAOWB DAIC Y MAOWG	2012	Surface and Coatings2012，206，18：	1
	14	PINCH-1 promotes tubular epithelial- to-mesenchymal transition by interacting with integrin-linked kinase 显示文摘	LiY DaiC Wu C	2007	JAm SocNephro2007，18，9：	1
	15	Hepatocytegrowthfactorattenuatesliverfibrosisinducedbybileductligation显示文摘	XiaJL DaiC MichalopoulosGK etal	2006	AmJPathol2006，168，5：	1
	16	Epithelial-to-mesenchymal transi-tion is a potential pathway leading to podocyte dysfunction andproteinuria显示文摘	LIY KANG Y S DAIC etal	2008	Am J Pathol2008，172，2：	1
	17	Optimized al- gorithms for predictive range and kNN queries on moving objects 显示文摘	Zhanga R Jagadishb H V Daic B T	2010	Information Systems2010，35，8：	1

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费