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6篇 您的检索式：作者名="Daisy Li"

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		题名	作者	年代	出处	被引量
	1	Aneuploidy of chromosome 8 in circulating tumor cells correlates with prognosis in patients with advanced gastric cancer显示文摘Objective: Previous work indicated that aneuploidy of chromosome 8 in circulating tumor cells(CTCs)correlated with therapeutic efficacy for advanced gastric cancer(AGC) patients. In this follow-up study performed on the same population of AGC patients, we investigated whether and how aneuploidy of chromosome 8 in CTCs correlates with patients' clinical prognosis.Methods: The prospective study was performed on 31 patients with newly diagnosed AGC. Previously established integrated subtraction enrichment(SE) and immunostaining-fluorescence in situ hybridization(i FISH)platform was applied to identify, enumerate and characterize CTCs. Quantification of CTCs and analysis of their aneuploidy of chromosome 8 were performed on patients before and after therapy.Results: CTCs were measured in 93.5% of AGC patients, and two CTC subtypes with diverse threshold values were identified, multiploid CTCs with the threshold of ≥2 per 7.5 m L and multiploid plus triploid CTCs with the threshold of ≥4, which were found to significantly correlate with poor progression-free survival(PFS) and overall survival(OS). In particular, patients with ≥10% increased multiploid CTCs after an initial 6 weeks of therapy had poor PFS and OS, whereas improved PFS and OS were observed on those who had ≥10% decreased multiploid CTCs. After adjusting for clinically significant factors, ≥10% increased post-therapy multiploid CTCs was the only independent predictor of PFS and OS.Conclusions: Aneuploidy of CTCs correlates with prognosis of AGC patients. Quantitative comparison monitoring multiploid CTCs before and after therapy may help predict improved or inferior prognosis and chemoresistance.	Yilin Li Xiaotian Zhang Jifang Gong Qiyue Zhang Jing Gao Yanshuo Cao Daisy Dandan Wang Peter Ping Lin Lin Shen	2016	Chinese Journal of Cancer Research2016，28，6：	7
	2	The impact of monetary policy shocks on stock prices: Evidence from Canada and the United States显示文摘	Yun Daisy Li Talan B. ??can Kuan Xu	2010	Journal of International Money and Finance2010，，5：	1
	3	Ds transposon is biased towards providing splice donor sites for exonization in transgenic tobacco显示文摘	Kuo-Chan Huang Hsiu-Chun Yang Kuan-Te Li Li-yu Daisy Liu Yuh-Chyang Charng	2012	Plant Molecular Biology2012，，4：	1
	4	The Impact of Monetary Policy Shocks on Stock Prices: Evidence from Canada and the United States 显示文摘	Yun Daisy Li Talan B Iscan Kuan Xu	2010	Journal of International Money and Finance2010，，29：	1
	5	Cell cycle-related kinase is a direct androgen receptor-regulated gene that drives [Beta]-catenin/T cell factor-dependent hepatocarcinogenesis显示文摘	Feng Hai Cheng Alfred S L Tsang Daisy P Li May S Go Minnie Y Cheung Yue S Zhao Gui-jun Ng Samuel S Lin Marie C Yu Jun Lai Paul B To Ka F Sung Joseph J Y	2011	Journal of Clinical Investigation2011，，8：	1
	6	Mathematical and computational analysis of CRISPR Cas9 sgRNA off-target homologies显示文摘	Michael Zhou Daisy Li Xiaoli Huan Joseph Manthey Ekaterina Lioutikova Hong Zhou	2017	International Journal of Biomathematics2017，10，6：	0

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