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| 1 | 澳大利亚临床共识指南:儿童卒中的诊断和急性期处理显示文摘卒中是导致儿童死亡的十大原因之一,幸存的致残患儿将面临几十年的残疾生活,给患儿及其家庭带来了巨大负担。由于安全性和有效性的证据有限,以及诊断的延误,目前卒中患儿无法接受再灌注治疗。儿童卒中诊断和急性期处理的澳大利亚临床共识指南,旨在最大限度地减少临床诊疗中的不确定性,并记录与成人卒中不同的危险因素、病因和假性卒中情况的最佳证据。临床问题的阐述来自于对2007年至2017年数据库的系统检索,但仅限于英语和儿科研究。该指南应用SIGN方法和国家健康与医学研究委员会系统对证据进行筛选和分类,通过推荐、评估、发展和评价系统(GRADE系统)对推荐进行强弱分级。该指南提供了60多项基于证据的推荐,以帮助参与院前和急症处理的临床医师快速识别儿童卒中,选择最合适的初步检查方案来确定诊断、明确病因,并选择最恰当的干预措施以挽救脑组织、预防复发。同时,指南也提供了颅内压和先天性心脏病管理方面的推荐。该指南的实施需要将院前和急诊系统重组,包括建立区域性卒中网络,建立儿科卒中疾病编码,快速MRI,以及对能够提供再灌注治疗的初级儿科卒中中心进行认证。该指南能够审核治疗的基准时间线,获得急性期的干预措施及预后判断。它还将促进澳大利亚儿童卒中登记的发展,并与国际登记处建立数据联系,以便准确收集卒中发病率、治疗和结果相关的数据。 | Medley TL Miteff C Andrews I Ware T Cheung M Monagle P Mandelstam S Wray A Pridmore C Troedson C Dale RC Fahey M Sinclair A Walsh P Stojanovski S Macka MT 徐佳丽(译) 吴川杰(译) 肖潇(译) 吕俊萱(译) 张博维(译) 吉训明(译) | 2019 | 中国脑血管病杂志2019，16，4： | 9 |
| 2 | Processing of low-density silica gel by critical point drying or ambient pressure drying显示文摘 | Valerie D Land Thomas M Harris Dale C Teeters | 2001 | Journal of Non-Crystalline Solids2001，，1： | 2 |
| 3 | Evolution of endovascular mechanical thrombectomy for acute ischemic stroke显示文摘Acute ischemic stroke(AIS) is a common medical problem associated with significant morbidity and mortality worldwide. A small proportion of AIS patients meet eligibility criteria for intravenous thrombolysis(IVT) with recombinant tissue plasminogen activator, and its efficacy for large vessel occlusion is poor. Therefore, an increasing number of patients with AIS are being treated with endovascular mechanical thrombectomy when IVT is ineffective or contraindicated. Rapid advancement in catheter-based and endovascular device technology has led to significant improvements in rates of cerebral reperfusion with these devices. Stentrievers and modern aspiration catheters have now surpassed earlier generation devices in the degree and rapidity of revascularization. This progress has been achieved with no concurrent increase in risk of major complications or mortality, both when used alone or in combination with IVT. The initial randomized controlled trials comparing endovascular therapy to IVT for AIS failed to show superior outcomes with endovascular treatment, butkey limitations of each trial may limit the significance of these results to current practice. While endovascular devices and operator experience continue to evolve, we are optimistic that this will be accompanied by improvements in patient outcomes. This review highlights the major endovascular devices used in current practice and the trials which have investigated their efficacy. | Colin J Przybylowski Dale Ding Robert M Starke Christopher R Durst R Webster Crowley Kenneth C Liu | 2014 | World Journal of Clinical Cases2014，2，11： | 2 |
| 4 | Gene transfers with subsequent removal of the selection gene from the host genome显示文摘 | Dale E C Ow D W | 1991 | Proc Natl Acad Sci USA1991，88，10： | 2 |
| 5 | Features of promising technologies for pretreatment of lignocellulosic biomass显示文摘 | MOSIER N WYMAN C DALE B | 2005 | Bioresource Technology2005，96，： | 1 |
| 6 | Intra- and intermolecular site-specific recombination in plant cells mediated by bacteriophage P1 recombinase 显示文摘 | Dale E C Ow D W | 1990 | Gene1990，91，1： | 1 |
| 7 | Acute disseminated encephalomyelitis, multiphasic disseminated encephalomyelitis and multiple sclerosis in children 显示文摘 | Dale RC de Sousa C Chong WK | 2000 | Brain2000，2，12312： | 1 |
| 8 | High-level expression of the rat whey acidic protein gene is mediated by elements in the promoter and 3' untranslated region显示文摘 | Dale T C Krnacik M J Schmidhouser C | 1992 | Mol Cell Biol1992，12，3： | 1 |
| 9 | Analysis of the isopentenyl diphosphate isomerase gene family from Arabidopsis thaliana显示文摘 | Michael C Frederick MH C Dale P | 1998 | Plant Mol Bio11998，36，： | 1 |
| 10 | Diabetes melli-tus and risk of fatal ischaemic heart disease by gender : 18years follow 显示文摘 | Wiseth R Dale A C Nilsen T I | 2007 | European Heart Journal2007，28，23： | 1 |
| 11 | Magnetic properties of ultrafine iron particles 显示文摘 | Gangopadhyay S Hadjipanayis G C Dale B | 1992 | Phys Rev B1992，45，： | 1 |
| 12 | Coordinated development of leading biomass pretreatment technologies显示文摘 | Wyman C E Dale B E Elander R T | 2005 | Bioresour Technol2005，96，18： | 1 |
| 13 | Field performance of transgenic potato plants compared with controls regenerated from tuber discs and shoot cuttings显示文摘 | Dale P J Mcpartlan H C | 1992 | Theor Appl Genet1992，84，： | 1 |
| 14 | Intra-and intermolecular site-specific recombination in plant cells mediated by bacteriophage P1 recombinase显示文摘 | DALE E C OW D W | 1990 | Gene1990，91，： | 1 |
| 15 | Automatic parcellation of human cortical gyri and sulci using standardanatomical nomenclature显示文摘 | Destrieux C Fischl B Dale A | 2010 | Neurolmage2010，53，1： | 1 |
| 16 | Expected and unexpected stressors in major international competition:appraisal coping,and performance显示文摘 | GORDON S | 2000 | The Sport Psychologist2000，，16： | 1 |
| 17 | Features of promising technologies for pretreatment of lignocellulosic biomass显示文摘 | Mosier N Wyman C Dale B | 2005 | Bioresour technol2005，96，6： | 1 |
| 18 | lsoprenyl diphns- phale synthases: protein sequence comparisons, a phylogenetic tree, and predictions of secondary structure 显示文摘 | Chen Anjun Panlos A Kroon C Dale Poulter | 1994 | Protein Sei1994，3，： | 1 |
| 19 | Improving protein solubility through rationally designed amino aeid replacemcnts: solubilization of the trimethoprim-resistant type S1 dihydrofolate reductase显示文摘 | Dale G E Broger C Langen H | 1994 | Protein Engineering Design and Selection1994，，7： | 1 |
| 20 | Features of promising tech?nologies for pretreatment of lignocellulosic biomass显示文摘 | Mosier N Wyman C Dale B | 2005 | Biore?source Technology2005，96，6： | 1 |
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