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| 1 | Ketamine use in current clinical practice显示文摘在市场上的将近半个世纪以后, ketamine 仍然在治疗疼痛的麻醉学者或临床医生的医药一套设备占据一个唯一的角落。在最后二十年,许多研究被进行了加亮行动的药机制,明确地那些它的 enantiomers。现在, ketamine 也在紧急情况部门为小儿科的疼痛控制正在被利用,与它在剧烈、长期的疼痛管理被揭示的反痛觉过敏、反煽动性的效果。最近,新卓见被逼近了反压抑的 ketamines 潜力和 antisuicidal 效果。当也在各种各样的临床的背景讨论 ketamine 管理的潜在的好处和风险时,这篇文章提供药 pharmacokinetics 和药效学的概述。 | Mei GAO Damoon REJAEI Hong LIU | 2016 | Acta Pharmacologica Sinica2016,37,7: | 11 |
| 2 | Phytochemistry,pharmacology,and therapeutic uses of black seed(Nigella sativa)显示文摘Black seed(Nigella sativa) is an annual flowering plant from Ranunculaceae family, native to southwest Asia. This plant has many food and medicinal uses. The use of its seeds and oil is common for treatment of many diseases, including rheumatoid arthritis, asthma, inflammatory diseases, diabetes and digestive diseases. The purpose of this study was to provide a comprehensive review on the scientific reports that have been published about N. sativa. The facts and statistics presented in this review article were gathered from the journals accessible in creditable databases such as Science Direct, Medline, Pub Med, Scopus, EBSCO, EMBASE, SID and Iran Medex. The keywords searched in Persian and English books on medicinal plants and traditional medicine, as well as the above reputable databases were 'Black seed', 'Nigella sativa', 'therapeutic effect', and 'medicinal plant'. The results showed that N. sativa has many biological effects such as anti-inflammatory, anti-hyperlipidemic, anti-microbial, anti-cancer, anti-oxidant, anti-diabetic, anti-hypertensive, and wound healing activities. It also has effects on reproductive, digestive, immune and central nervous systems, such as anticonvulsant and analgesic activities. In summary, it can be used as a valuable plant for production of new drugs for treatment of many diseases. | Wesam Kooti Zahra Hasanzadeh-Noohi Naim Sharafi-Ahvazi Majid Asadl-Samani Damoon Ashtary-Larky | 2016 | Chinese Journal of Natural Medicines2016,14,10: | 5 |
| 3 | Seismic ground amplification induced by box-shaped tunnels显示文摘The growing use of underground structures,specifically to facilitate urban transportation,highlights the need to scrutinize the effects of such spaces on the seismic ground response as well as the surrounding buildings.In this regard,the seismic ground amplification variations in the vicinity of single and twin box-shaped tunnels subjected to SV waves have been investigated by the finite difference method.To evaluate the effects,generalizable dimensionless diagrams based on the results of parametric numerical analysis considering factors such as variations in the tunnels′depth,the distances between the tunnels,tunnel lining flexibility,and input wave frequency,have been presented.In addition,to assess the effects of underground box-shaped tunnels on the response spectrum of the ground surface,seven selected accelerograms have been matched based on a specific design spectrum for the stiff soil condition of Eurocode 8(CEN,2006).The results underline the significant amplification effect of the box-shaped tunnels on the ground motions,specifically in the case of horizontal twin tunnels,which should be given more attention in current seismic design practices for surface structures. | Damoon Feizi Jafar Asgari Marnani Hamid Alielahi Mehdi Panji | 2022 | Earthquake Engineering and Engineering Vibration2022,21,3: | 1 |
| 4 | Protection of Rear Seat Occupants in Frontal Crashes, Controlling for Occupant and Crash Characteristics显示文摘 | Sahraei Elham Soudbakhsh Damoon Digges Kennerly | 2009 | Stapp Car Crash Journal2009,,: | 1 |