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28篇 您的检索式:作者名="Daniel AA"
    题名 作者 年代 出处 被引量
1Juvenile polyposis syndrome显示文摘Juvenile polyposis syndrome is a rare autosomal dominant syndrome characterized by multiple distinct juvenile polyps in the gastrointestinal tract and an increased risk of colorectal cancer.The cumulative life-time risk of colorectal cancer is 39% and the relative risk is 34.Juvenile polyps have a distinctive histology characterized by an abundance of edematous lamina propria with inflammatory cells and cystically dilated glands lined by cuboidal to columnar epithelium with reactive changes.Clinically,juvenile polyposis syndrome is defined by the presence of 5 or more juvenile polyps in the colorectum,juvenile polyps throughout the gastrointestinal tract or any number of juvenile polyps and a positive family history of juvenile polyposis.In about 50%-60% of patients diagnosed with juvenile polyposis syndrome a germline mutation in the SMAD4 or BMPR1A gene is found.Both genes play a role in the BMP/TGF-beta signalling pathway.It has been suggested that cancer in juvenile polyposis may develop through the socalled 'landscaper mechanism' where an abnormal stromal environment leads to neoplastic transformation of the adjacent epithelium and in the end invasive carcinoma.Recognition of this rare disorder is important for patients and their families with regard to treatment,follow-up and screening of at risk individuals.Each clinician confronted with the diagnosis of a juvenile polyp should therefore consider the possibility of juvenile polyposis syndrome.In addition,juvenile polyposis syndrome provides a unique model to study colorectal cancer pathogenesis in general and gives insight in the molecular genetic basis of cancer.This review discusses clinical manifestations,genetics,pathogenesis and management of juvenile polyposis syndrome.Lodewijk AA Brosens Danielle Langeveld W Arnout van Hattem Francis M Giardiello G Johan A Offerhaus 2011World Journal of Gastroenterology2011,17,44:7
2Criteria for improvement in rheumatoid arthritis: alternatives to the Ameri- can college ofrheumatology 20显示文摘Daniel AA Grale H George D 2004JRheumatol2004,31,5:1
3Estrogenic activity removal of 1713-estradiol by ozonation and identification of by-products显示文摘Daniele B Antonio FM D6bora de AA 2007Chemosphere2007,69,5:1
4Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbation of sehizophrenia显示文摘Casey DE Daniel DG Wassef AA 2003Neuropsychopharmaeology2003,28,:1
5Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbation of schizophrenia显示文摘 Daniel DG Wassef AA 2003Neuropsychophar macology2003,28,:1
6Traumatic spondyloptosis resulting from high-energy trauma concurrent with a tonic-clonic seizure显示文摘Daniels AH Deodhar AA Hart RA 2009Spine J2009,9,:1
7Race: an explanation of patient compliance: fact of fiction显示文摘Danels DE Rene AA Daniels VR 1994J Nat Med Assoc1994,8,6:1
8Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbation of schophrenia 显示文摘Casey DE Daniel DG Wassef AA 2003Neuropsychopharmacolgy2003,28,:1
9Granular cell tumours of the orbit显示文摘McNab AA Daniel SE 1991Aust N Z J Ophthalmol1991,19,1:1
10Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbation of schizophrenia显示文摘 Daniel DG Wassef AA 2003Neuropsychopharmacology2003,28,:1
11Contrast sensitivity and glare disability after radial keratotomy and photorefractive keratectomy显示文摘 Daniell J Stulting RD 1998Arch Ophthalmol1998,116,1:1
12Effect of divalproex com-bined with olanzapine or risperidone in patients with an acute exacerbation of schizophrenia 显示文摘Casey DE Daniel DG Wassef AA 2003Neuropsychopharmacology2003,28,:1
13Lymphoma involving the breast显示文摘Daniel AA Jean FS Lawrence MW 1994Am J Surg Pathol1994,18,3:1
14Effect of divalproex combined with olanzapine or risperidone in patients with all acute exacerbation of schizophrenia显示文摘 Daniel DG Wassef AA 2003Neuropsychopharmacology2003,28,:1
15Systolic blood pressure in childhood predicts hypertension and metabolic syndrome later in life显示文摘Sun SS Grave GD Siervogel RM Pickoff AA Arslanian SS Daniels SR 0,,02:1
16Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbation of schizophrenia 显示文摘Casey DE Daniel DG Wassef AA 2003Neuropsychopharmacology2003,28,1:1
17The orphan Gprotein-coupled receptors GPR41 and GPR43are activated by propionate and other short chain carboxylic acids显示文摘Brown AJ Goldsworthy SM Barnes AA Eilert MM Tcheang L Daniels D 2003J Biol Chem2003,278,11:1
18Traumatic spondyloptosis re-suhing from high-energy trauma concurrent with a tonic-clonic seizure显示文摘Daniels AH Deodhar AA Hart RA 2009Spine J2009,9,1:1
19Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbution of schizophrenia 显示文摘Casey DE Daniel DG Massef AA 2003Neuropsychopharmacology2003,28,:1
20Angiotropic lymphoma: an immunophenotypically and clinocally heterogeneous lymphoma显示文摘 Robert C Daniel AA 2001Modern Pathology2001,14,11:1
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