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| 1 | Do ankle braces provide similar effects on ankle biomechanical variables in subjects with and without chronic ankle instability during landing?显示文摘Purpose:The purpose of this study was to examine effects of a sport version of a semi-rigid ankle brace(ElementTM) and a soft ankle brace (ASO) on ankle biomechanics and ground reaction forces(GRFs) during a drop landing activity in subjects with chronic ankle instability(CAD compared to healthy subjects with no history of CAI. Methods:Ten healthy subjects and 10 subjects who had multiple ankle sprains participated in the study as the control and unstable subjects, respectively.The CAI subjects were age,body mass index and gender matched with the control subjects.The arch index and ankle functions of the subjects were measured in a subject screening session.During the biomechanical test session,participants performed five trials of drop landing from 0.6 m,wearing no brace(NB).Element? brace and ASO brace.Simultaneous recording of three-dimensional kinematic(240 Hz) and GRF(1200 Hz) data were performed. Results:The CAI subjects had lower ankle functional survey scores.The arch index and deformity results showed greater arch deformity of ElementTM against a static load than in NB and ASO due to greater initial arch position held by the brace.CAI participants had greater eversion velocity than healthy controls.The ASO brace reduced the first peak vertical GRF whereas ElementTM increased 2nd peak vertical GRF. ElementTMbrace reduced eversion range of motion(ROM) and peak eversion velocity compared to NB and ASO.In addition,ElementTM reduced dorsiflexion ROM and increased peak plantarflexion moment compared to NB and ASO. Conclusion:Results of static arch measurements and dynamic ankle motion suggest that the restrictions offered by both braces are in part due to more dorsiflexed ankle positions at contact,and higher initial arch position and stiffer ankle for ElementTM. | Songning Zhang Michael Wortley Julia Freedman Silvernail Daniel Carson Maxime R.Paquette | 2012 | Journal of Sport and Health Science2012，1，2： | 5 |
| 2 | Ron receptor-dependent gene regulation in a mouse model of endotoxin-induced acute liver failure显示文摘BACKGROUND:Prior experimentation has shown that loss of the tyrosine kinase(TK) signaling domain of the Ron receptor leads to marked hepatocyte protection in a model of lipopolysaccharideinduced acute liver failure(ALF) in D-galactosamine(GalN)sensitized mice.The aim of this study was to identify the role of Ron in the regulation of hepatic gene expression.METHODS:Microarray analyses were performed on liver RNA isolated sequentially from wild-type(WT) and TK-/mice during the progression of ALF.Gene array data were validated using Western and immunohistochemistry analyses as well as with ex vivo culture systems.RESULTS:At baseline,101 genes were differentially expressed between WT and TK-/-livers,which regulate processes involved in hypoxia,proliferation,apoptosis and metabolism.One hour after ALF induction,WT livers exhibited increased cytokine expression compared to TK-/-livers,and after 4 hours,an induction of suppressor of cytokine signaling(SOCS) genes as well as JAK-STAT pathway activation were prominent in TK-/livers compared to controls.CONCLUSION:Our studies suggest a novel hepato-protective mechanism in Ron TK-/-mice wherein increased and sustained SOCS production and JAK-STAT activation in the hepatocyte may inhibit the destructive proinflammatory milieu and promote survival factors which blunt hepatic death and the ensuing development of ALF. | Rishikesh M Kulkarni Louis W Kutcher William D Stuart Daniel J Carson Mike A Leonis Susan E Waltz | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，4： | 3 |
| 3 | Issues which Impact upon Marketing in the Small Firm显示文摘 | Danielle Mc Cartan-Quinn David Carson | 2003 | Small Business Economics2003，，2： | 1 |
| 4 | A randomized, double-blind, placebo-controlled, study of the efficacy and safety of aripiprazole 10,15 or 20 mg/day for the treatment of patients with acute exacerbations of schizophrenia 显示文摘 | McEvoy JP Daniel DG Carson WH Jr | 2007 | J Psychiatr Res2007，41，11： | 1 |
| 5 | Reliability, Validity, and Factor Structure of the Creative Achievement Questionnaire显示文摘 | Shelley H. Carson Jordan B. Peterson Daniel M. Higgins | 2005 | Creativity Research Journal2005，，1： | 1 |
| 6 | Stereotactic Radiosurgery in the Management of Brain Metastases: An Institutional Retrospective Analysis of Survival显示文摘 | James L. Frazier Sachin Batra Sumit Kapor Ananth Vellimana Rahul Gandhi Kathryn A. Carson Ori Shokek Michael Lim Lawrence Kleinberg Daniele Rigamonti | 2010 | International Journal of Radiation Oncology, Biology, Physics2010，，5： | 1 |
| 7 | Rapidly progressive metastatic multicentric epithelioid angiosarcoma of the small bowel:a case report and a review of literature显示文摘 | Grewal JS Daniel AR Carson EJ | 2008 | Iut J Colorectal Dis2008，23，8： | 1 |
| 8 | Current status of the Cincinnati GCL test plots显示文摘 | Robert M Koerner David A Carson David E Daniel | 1997 | Geotextiles and Geomembranes1997，，31： | 1 |
| 9 | A randomized, double- blind, placebo-controlled study of the efficacy and safety of aripi- prazolel0, 15 or 20 rag/day for the treatment of patients with acute ex- acerbations of schizophrenia显示文摘 | McEvoy JP Daniel DG Carson WH Jr | 2007 | Psychiatr Res2007，41，： | 1 |
| 10 | Rapidly progressive metastatic multicentric epithelioid angiosarcoma of the small bowel: a case report and a review of literature显示文摘 | Jaspreet S. Grewal Amudha R. M. Daniel Erik J. Carson Andrew T. Catanzaro Thomas M. Shehab Joseph A. Tworek | 2008 | International Journal of Colorectal Disease2008，，8： | 1 |
| 11 | Sentinel node biopsy in breast cancer显示文摘 | John M. Barnwell MD Mark A. Arredondo MD Daniel Kollmorgen MD John F. Gibbs MD Dominick Lamonica MD William Carson MD Paul Zhang MD Janet Winston MD Stephen B. Edge MD | 1998 | Annals of Surgical Oncology1998，，2： | 1 |
| 12 | In Vivo Imaging of Endogenous Pancreatic [Beta]-Cell Mass in Healthy and Type 1 Diabetic Subjects Using ^sup 18^F-Fluoropropyl-Dihydrotetrabenazine and PET显示文摘 | Normandin Marc D Petersen Kitt F Ding Yu-Shin Lin Shu-Fei Naik Sarita Fowles Krista Skovronsky Daniel M Herold Kevan C McCarthy Timothy J Calle Roberto A Carson Richard E Treadway Judith L Cline Gary W | 2012 | EN2012，，6： | 1 |
| 13 | A randomized,double-blind,placebo-controlled,study of the efficacy and safety of aripi-prazole10,15or20mg/day for the treatment of patients with acute exacerbations of schizophrenia显示文摘 | McEvoy JP Daniel DG Carson WH Jr | 2007 | J Psychiatr Res2007，41，11： | 1 |
| 14 | A random- ized, double - blind, placebo - controlled, study of the efficacy and safety of aripiprazole 10, 15 or 20 mg/day for the treatment of patients with acute exacerbations of schizophrenia显示文摘 | McEVOY J P DANIEL D G CARSON W H Jr | 2007 | J Psychiatr Res2007，41，11： | 1 |
| 15 | Disturbance history,species diversity,and structural complexity of a temperate deciduous forest显示文摘Stand structural complexity enhancement is an increasingly popular management objective,especially on public lands.Complex stand structures are hypothesized to support a relatively high degree of native forest diversity and be more resistant and resilient to disturbances.Complex structures are characterized by the presence of deadwood and heterogeneity of tree-size classes and tree architecture.Relatively little is known about how discrete disturbance events affect structural complexity and compositional diversity in Quercus-dominated stands at fine spatial scales(i.e.neighborhoods).We established 200.05 ha fixed-radius plots on the Sipsey Wilderness of William B.Bankhead National Forest in northern Alabama to quantify woody plant species composition and structure.Trees were mapped on each plot to quantify overstory structural complexity and compositional diversity.We extracted two cores from all canopy Quercus spp.C 5 cm diameter at breast height to quantify age,recruitment pulses,and reconstruct canopy disturbance history.Shannon species diversity in the sampled area was 1.75 for trees,2.08 for saplings,and 1.69 for seedlings.Quercus alba had the greatest basal area,and Ostrya virginiana had the highest density.The stand exhibited a reverse J-shaped distribution with a q-factor of 1.72.The oldest Quercus dated to 1795,and the largest recruitment pulse occurred in the 1870s.The mean return interval for intermediateseverity disturbance was 38 years.Although we documented no relationships between disturbance frequency and compositional diversity at the neighborhood scale(0.05 ha),less frequent disturbance was associated with higher structural complexity(r^2=0.258,p=0.026)at the neighborhood scale.We suggest that localized disturbance increases species diversity and structural complexity,but these processes are manifest at the stand level and not at the neighborhood scale.We conclude that the spatial variability(i.e.size,shape,orientation,microsite conditions)is likely more influential on diversity and complexity than the temporal variation(frequency)of these processes at the neighborhood scale. | Jonathan D.Goode Carson R.Barefoot Justin L.Hart Daniel C.Dey | 2020 | Journal of Forestry Research2020，31，2： | 0 |
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