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| 1 | Optical disassembly of cellular clusters by tunable ‘tug-of-war’ tweezers显示文摘Bacterial biofilms underlie many persistent infections,posing major hurdles in antibiotic treatment.Here we design and demonstrate‘tug-of-war’optical tweezers that can facilitate the assessment of cell–cell adhesion—a key contributing factor to biofilm development,thanks to the combined actions of optical scattering and gradient forces.With a customized optical landscape distinct from that of conventional tweezers,not only can such‘tug-of-war’tweezers stably trap and stretch a rod-shaped bacterium in the observing plane,but,more importantly,they can also impose a tunable lateral force that pulls apart cellular clusters without any tethering or mechanical movement.As a proof of principle,we examined a Sinorhizobium meliloti strain that forms robust biofilms and found that the strength of intercellular adhesion depends on the growth medium.This technique may herald new photonic tools for optical manipulation and biofilm study,as well as other biological applications. | Anna S Bezryadina Daryl C Preece Joseph C Chen Zhigang Chen | 2016 | Light(Science & Applications)2016,5,1: | 4 |
| 2 | Saturable pharmacokinetics and paclitaxel pharmacodynamics in children with solid tumor显示文摘 | Craig A Charles B | 1994 | J Clin Oncol1994,12,3: | 1 |
| 3 | Mining single-nucleo- tide polymorphisms from hexaploid wheat ESTs显示文摘 | Daryl J S Robert K Mariko M | 2003 | Genome2003,49,: | 1 |
| 4 | Postharvest physiology and vola-tile production by flowers of Ptilotus nobilis显示文摘 | Amanda J A Heather S Daryl J | 2014 | Postharvest Biolo-gy and Technology2014,88,: | 1 |
| 5 | Estimating Genetic Coefficients for the CSM-CERES-Maize Model in North Carolina Environments显示文摘 | Yang Zhengyu Wilkerson Gail G Buol Gregory S Bowman Daryl T Heiniger Ronnie W | 2009 | Agronomy Journal2009,,5: | 1 |
| 6 | Uterine perforation and migration of an ntrauterine contraceptive device in a 24-year- old patient seeking care for abdominal pain 显示文摘 | Michelle Barber MSW Daryl S | 2011 | Journal of Chi-ropractic Medicine2011,10,: | 1 |
| 7 | The impact of specialized oncology nursing on patient supportive care outcomes 显示文摘 | Jonathan S Doris H Daryl B | 2011 | J Psychosoc Oncol2011,29,3: | 1 |
| 8 | Predictions of 2010's tropical cyclones using the GFS and ensemble-based data assimila-tion methods显示文摘 | Hamill T M Whitaker J S Daryl T | | 0,,10: | 1 |
| 9 | Valuing the physically active life:Contemporary andfuture directions显示文摘 | DARYL S | 1996 | Quest1996,48,3: | 1 |
| 10 | Molecular Confinement Influen-ces Protein Structure and Enhances Thermal Proterin Stabil-ity显示文摘 | Daryl K Eggers A Joan S | 2001 | Protein Sei2001,10,: | 1 |
| 11 | Scale factor non-linearity of a body dither laser gyro显示文摘 | THOMAS J H DARYL C S | 1978 | J IEEE1978,66,5: | 1 |
| 12 | Health Insurance Status and the Care of Nursing Home Resi- dents with Advanced Dementia显示文摘 | Keith S Goldfeld David C Grabowski Daryl J Caudry | 2013 | Published in final edited form as: JAMA Intern Med2013,173,22: | 1 |
| 13 | External Demand for Hong / Kong Dollar Currency (revisited) 显示文摘 | DARYL H S JIMM J SHI | 2006 | HKMA Quarterly Bulletin2006,,3: | 1 |
| 14 | A fi- nite-element model of the mechanical effects of implant- able microelectrodes in the cerebral cortex 显示文摘 | JEYAKUMAR S MARTIN D C DARYL R K | 2005 | Journal of Neural Engineering2005,2,4: | 1 |
| 15 | Cyclosporin A inhibits chromium(VI)-induced apoptosis and mitochondrial cytochrome c release and restores clonogenic survival in CHO cells 显示文摘 | DARYL P E JATINDER S DIANE C L | 2000 | Carcinogenesis2000,21,11: | 1 |
| 16 | Coherent random radar imaging显示文摘 | Xu Xiaojian Daryl C B Dmitriy S G | 2002 | The First International Workshop on the Noise Radar Technology Yalta Crimea UKRAINE2002,2002,: | 1 |
| 17 | Predictors of Rehemorrhage After Treatment of Ruptured Intracranial Aneurysms: The Cerebral Aneurysm Rerupture After Treatment (CARAT) Study显示文摘 | S Claiborne Johnston Christopher F. Dowd Randall T. Higashida Michael T. Lawton Gary R. Duckwiler Daryl R. Gress | 2008 | Stroke2008,,1: | 1 |
| 18 | Endoscopic ultrasound fine-needle biopsy vs fine-needle aspiration for lymph nodes tissue acquisition:a systematic review and meta-analysis显示文摘Background:Endoscopic ultrasound(EUS)-guided tissue acquisition represents the choice of methods for suspected lymph nodes(LNs)located next to the gastrointestinal tract.This study aimed to compare the pooled diagnostic performance of EUS-guided fine-needle biopsy(EUS-FNB)and fine-needle aspiration(EUS-FNA)for LNs sampling.Methods:We searched PubMed/MedLine and Embase databases through August 2021.Primary outcome was diagnostic accuracy;secondary outcomes were sensitivity,specificity,sample adequacy,optimal histological core procurement,number of passes,and adverse events.We performed a pairwise meta-analysis using a random-effects model.The results are presented as odds ratio(OR)or mean difference along with 95%confidence interval(CI).Results:We identified nine studies(1,276 patients)in this meta-analysis.Among these patients,66.4%were male;the median age was 67 years.Diagnostic accuracy was not significantly different between the two approaches(OR,1.31;95%CI,0.81–2.10;P=0.270).The accuracy of EUS-FNB was significantly higher when being performed with newer end-cutting needles(OR,1.87;95%CI,1.17–3.00;P=0.009)and in abdominal LNs(OR,2.48;95%CI,1.52–4.05;P<0.001)than that of EUSFNA.No difference in terms of sample adequacy was observed between the two approaches(OR,1.40;95%CI,0.46–4.26;P=0.550);however,histological core procurement and diagnostic sensitivity with EUS-FNB were significantly higher than those with EUS-FNA(OR,6.15;95%CI,1.51–25.07;P=0.010 and OR,1.87;95%CI,1.27–2.74,P=0.001).The number of needle passes needed was significantly lower in the EUS-FNB group than in the EUS-FNA group(mean difference,-0.54;95%CI,-0.97 to -0.12;P=0.010).Conclusions EUS-FNA and EUS-FNB perform similarly in LN sampling;however,FNB performed with end-cutting needles outperformed FNA in terms of diagnostic accuracy. | Antonio Facciorusso Stefano Francesco Crino Paraskevas Gkolfakis Daryl Ramai Andrea Lisotti Ioannis S Papanikolaou Benedetto Mangiavillano Ilaria Tarantino Andrea Anderloni Carlo Fabbri Konstantinos Triantafyllou Pietro Fusaroli | 2022 | Gastroenterology Report2022,10,1: | 0 |
| 19 | Endoscopic cryotherapy:Indications,techniques,and outcomes involving the gastrointestinal tract显示文摘Endoscopic cryotherapy is a technique utilized for the ablation of target tissue within the gastrointestinal tract.A cryotherapy system utilizes the endoscopic application of cryogen such as liquid nitrogen,carbon dioxide or liquid nitrous oxide.This leads to disruption of cell membranes,apoptosis,and thrombosis of local blood vessels within the target tissue.Several trials utilizing cryotherapy for Barrett’s esophagus(BE)with variable dysplasia,gastric antral vascular ectasia(GAVE),esophageal carcinoma,radiation proctitis,and metastatic esophageal carcinomas have shown safety and efficacy.More recently,liquid nitrogen cryotherapy(cryodilation)was shown to be safe and effective for the treatment of a benign esophageal stricture which was refractory to dilations,steroid injections,and stenting.Moreover,liquid nitrogen cryotherapy is associated with less post procedure pain as compared to radiofrequency ablation in BE with comparable ablation rates.In patients with GAVE,cryotherapy was found to be less tedious as compared to argon plasma coagulation.Adverse events from cryotherapy most commonly include chest pain,esophageal strictures,and bleeding.Gastric perforations did occur as well,but less often.In summary,endoscopic cryotherapy is a promising and growing field,which was first demonstrated in BE,but the use now spans for several other disease processes.Larger randomized controlled trials are needed before its role can be established for these different diseases. | Amaninder Dhaliwal Syed M Saghir Harmeet S Mashiana Annie Braseth Banreet S Dhindsa Daryl Ramai Pushpak Taunk Rene Gomez-Esquivel Aamir Dam Jason Klapman Douglas G Adler | 2022 | World Journal of Gastrointestinal Endoscopy2022,14,1: | 0 |