| 2 | Peripheral vestibular system: Age-related vestibular loss and associated deficits显示文摘Given the interdependence of multiple factors in age-related vestibular loss (e.g., balance, vision,cognition), it is important to examine the individual contributions of these factors with ARVL. While therelationship between the vestibular and visual systems has been well studied (Bronstein et al., 2015),little is known about the association of the peripheral vestibular system with neurodegenerative disorders (Cronin et al., 2017). Further, emerging research developments implicate the vestibular system asan opportunity for examining brain function beyond balance, and into other areas, such as cognition andpsychological functioning. Additionally, the bidirectional impact of psychological functioning is understudied in ARVL. Recognition of ARVL as part of a multifaceted aging process will help guide thedevelopment of integrated interventions for patients who remain at risk for decline. In this review, wewill discuss a wide variety of characteristics of the peripheral vestibular system and ARVL, how it relatesto neurodegenerative diseases, and correlations between ARVL and balance, vision, cognitive, and psychological dysfunction. We also discuss clinical implications as well as future directions for research, withan emphasis on improving care for patients with ARVL. | Jennifer Coto Carmen L.Alvarez Ivette Cejas Brett M.Colbert Bonnie E.Levin Joshua Huppert Tatjana Rundek Carey Balaban Susan H.Blanton David J.Lee David Loewenstein Michael Hoffer Xue Zhong Liu | 2021 | Journal of Otology2021，16，4： | 1 |
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