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| 1 | Factors associated with time to laparoscopic cholecystectomy for acute cholecystitis显示文摘AIM: To determine patient and process of care factors associated with performance of timely laparoscopic cholecystectomy for acute cholecystitis. METHODS: A retrospective medical record review of 88 consecutive patients with acute cholecystitis was conducted. Data collected included demographic data, co-morbidities, symptoms and physical findings at presentation, laboratory and radiological investigations, length of stay, complications, and admission service (medical or surgical). Patients not undergoing cholecystectomy during this hospitalization were excluded from analysis. Hierarchical generalized linear models were constructed to assess the association of pre-operative diagnostic procedures, presenting signs, and admitting service with time to surgery.RESULTS: Seventy cases met inclusion and exclusion criteria, among which 12 were admitted to the medical service and 58 to the surgical service. Mean ± SD time to surgery was 39.3 ± 43 h, with 87% of operations performed within 72 h of hospital arrival. In the adjusted models, longer time to surgery was associated with number of diagnostic studies and endoscopic retrograde cholangio-pancreatography (ERCP, P = 0.01) as well with admission to medical service without adjustment for ERCP (P < 0.05). Patients undergoing both magnetic resonance cholangiopancreatography (MRCP) and computed tomography (CT) scans experienced the longest waits for surgery. Patients admitted to the surgical versus medical service underwent surgery earlier (30.4 ± 34.9 vs 82.7 ± 55.1 h, P < 0.01), had less post-operative complications (12% vs 58%, P < 0.01), and shorter length of stay (4.3 ± 3.4 vs 8.1 ± 5.2 d, P < 0.01).CONCLUSION: Admission to the medical service and performance of numerous diagnostic procedures, ERCP, or MRCP combined with CT scan were associated with longer time to surgery. Expeditious performance of ERCP and MRCP and admission of medically stable patients with suspected cholecystitis to the surgical service to speed up time to surgery should be considered. | Chris N Daniak David Peretz Jonathan M Fine Yun Wang Alan K Meinke William B Hale | 2008 | World Journal of Gastroenterology2008，14，7： | 13 |
| 2 | Sentinel-lymph-node resection compared with conventional axillary-lymph-node dissection in clinically node-negative patients with breast cancer: overall survival findings from the NSABP B-32 randomised phase 3 trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Joseph P Costantino Takamaru Ashikaga Donald L Weaver Eleftherios P Mamounas Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Norman Wolmark | 2010 | Lancet Oncology2010，，10： | 3 |
| 3 | Technical outcomes of sentinel-lymph-node resection and conventional axillary-lymph-node dissection in patients with clinically node-negative breast cancer: results from the NSABP B-32 randomised phase III trial显示文摘 | David N Krag Stewart J Anderson Thomas B Julian Ann M Brown Seth P Harlow Takamaru Ashikaga Donald L Weaver Barbara J Miller Lynne M Jalovec Thomas G Frazier R Dirk Noyes André Robidoux Hugh MC Scarth Denise M Mammolito David R McCready Eleftherios P Mamo | 2007 | Lancet Oncology2007，，10： | 2 |
| 4 | Ecological Linkages Between Aboveground and Belowground Biota显示文摘 | DAVID A W RICHARD D B JOHN N K | 2004 | Science2004，304，： | 1 |
| 5 | Simultaneous measurement of phytoplanktonic primary production,nutrient and light availability along a turbid,eutrophic UK east coast estuary(the Colne Estuary)显示文摘 | ESRA K GRAHAM J C U DAVID B N | 2002 | Marine Ecology Progress Series2002，231，： | 1 |
| 6 | Negative pH and extremely acidic mine waters from ironmountain, Califomia显示文摘 | DARRELL K N CHARLES N A CAROL J P DAVID W B | 2000 | Environmental Science and Technology2000，34，： | 1 |
| 7 | Liver Fibrosis显示文摘 | RAMóN B DAVID A B | 2005 | J Clin Invest2005，115，： | 1 |
| 8 | High-pressure methane and carbon dioxide adsorption on dry and moisture-equilibrated Pennsylvanian coals显示文摘 | Krooss B M van Bergen F Gensterblum Y Siemons N Pagnier H J M David P | 2002 | Int J Coal Geol2002，51，2： | 1 |
| 9 | Efficiency of Financial Institutions: International Survey and Directions for Future Research 显示文摘 | Allen N Berger David B Humphrey | 1997 | European Journal of Operational Research1997，，98： | 1 |
| 10 | Host plant evaluation behaviour of Bemisia tabaci and its modification by external uptake of imidacloprid显示文摘 | RUFUS I MATTHEW C DAVID N B | 1999 | Physiol Entomol1999，24，： | 1 |
| 11 | High-Dose Split-Course Radiation Therapy for Anal Cancer: Outcome Analysis Regarding the Boost Strategy (CORS-03 Study)显示文摘 | Jean-Michel Hannoun-Levi Cécile Ortholan Michel Resbeut Eric Teissier Philippe Ronchin Didier Cowen Audrey Zaccariotto Karen Bénézery Eric Fran?ois Naji Salem Steve Ellis David Azria Jean-Pierre Gerard | 2011 | International Journal of Radiation Oncology Biology Physics2011，，3： | 1 |
| 12 | Mechanical properties of Al(Sc,Zr) alloys at ambient and elevated temperatures显示文摘 | Fuller Christian B Seidman David N Dunand David C | 2003 | Acta Materialia2003，51，： | 1 |
| 13 | A Reviewand Analysis of Current Computer-Aided Fixture DesignApproaches 显示文摘 | B O Y L E Iain R O N G Yiming B R O W N David C | 2011 | Robotics and Computer-Integrated Manufacturiiig2011，27，1： | 1 |
| 14 | Transparent conducting Nnc oxide thin films doped with aluminum and molybdenum显示文摘 | JOEL N D TIMOTHY A G DAVID M W TERESA M B MATTHEW Y BOBBY T TIMOTHY J C | 2007 | Journal V-acuum Society Technology2007，25，4： | 1 |
| 15 | Liver fibrosis显示文摘 | Ramón B David AB | 2005 | The Journal of Clinical Investigation2005，115，2： | 1 |
| 16 | Consistency conditions for regulatory analysis of financial institutions: a comparison of frontier efficiency methods 显示文摘 | Bauer Paul W Allen N Berger Gary D Ferrier and Humphrey David B | 1998 | Journal of Economics and Business1998，，50： | 1 |
| 17 | Medical management of hyperglycemia in type 2 Diabete:A consensus algorithm for the initiation and adjustment of therapy显示文摘 | David M Natha N John B | 2008 | Diabetes Care2008，31，12： | 1 |
| 18 | The physiology of bidirectional cavopulmonary connection 显示文摘 | ROBERT M DAVID M LEE N B | 1998 | Ann Thorac Surg1998，66，2： | 1 |
| 19 | 显示文摘 | David S M Michael B Robert E N | 1990 | J Am Ceram Soc1990，73，8： | 1 |
| 20 | P53 and Bax activation in 6-OH DA-induced apoptosis in PC12 cells 显示文摘 | David B Ying W Marie N | 1997 | Brain Res1997，751，： | 1 |
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