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| 1 | Prospective randomized controlled trial evaluating cap-assisted colonoscopy vs standard colonoscopy显示文摘AIM: To study the significance of cap-fitted colonoscopy in improving cecal intubation time and polyp detection rate. METHODS: This study was a prospective randomized controlled trial conducted from March 2008 to February 2009 in a tertiary referral hospital at Sydney. The primary end point was cecal intubation time and the secondary endpoint was polyp detection rate. Consecutive cases of total colonoscopy over a 1-year period were recruited. Randomization into either standard colonoscopy (SC) or cap-assisted colonoscopy (CAC) was performed after consent was obtained. For cases randomized to CAC, one of the three sizes of cap was used: D-201-15004 (with a diameter of 15.3 mm), D-201-14304 (14.6 mm) and D-201-12704 (13.0 mm). All of these caps were produced by Olympus Medical Systems, Japan. Independent predictors for faster cecal time and better polyp detection rate were also determined from this study. RESULTS: There were 200 cases in each group. There was no signif icant difference in terms of demographic characteristics between the two groups. CAC, when compared to the SC group, had no signif icant difference in terms of cecal intubation rate (96.0% vs 97.0%, P = 0.40) and time (9.94 ± 7.05 min vs 10.34 ± 6.82 min, P = 0.21), or polyp detection rate (32.8% vs 31.3%, P = 0.75). On the subgroup analysis, there was no significant difference in terms of cecal intubation time by trainees (88.1% vs 84.8%, P = 0.40), ileal intubation rate (82.5% vs 79.0%, P = 0.38) or total colonoscopy time (23.24 ± 13.95 min vs 22.56 ± 9.94 min, P = 0.88). On multivariate analysis, the independent determinants of faster cecal time were consultant-performed procedures (P < 0.001), male patients (P < 0.001), non-usage of hyoscine (P < 0.001) and better bowel preparation (P = 0.01). The determinants of better polyp detection rate were older age (P < 0.001), no history of previous abdominal surgery (P = 0.04), patients not having esophagogastroduodenoscopy in the same setting (P = 0.003), trainee-performed procedures (P = 0.01), usage of hyoscine (P = 0.01) and procedures performed for polyp follow-up (P = 0.01). The limitations of the study were that it was a single-center experience, no blinding was possible, and there were a large number of endoscopists. CONCLUSION: CAC did not signif icantly different from SC in term of cecal intubation time and polyp detection rate. | Hoi-Poh Tee Crispin Corte Hamdan Al-Ghamdi Emilia Prakoso John Darke Raman Chettiar Wassim Rahman Scott Davison Sean P Griffin Warwick S Selby Arthur J Kaffes | 2010 | World Journal of Gastroenterology2010,16,31: | 10 |
| 2 | Residual renal function in peritoneal dialysis with failed allograft and minimum immunosuppression显示文摘Immunosuppression(IS) is often withdrawn in patients with end stage renal disease secondary to a failed renal allograft, and this can lead to an accelerated loss of residual renal function(RRF). As maintenance of RRF appears to provide a survival benefit to peritoneal dialysis(PD) patients, it is not clear whether this benefit of maintaining RRF in failed allograft patients returning to PD outweigh the risks of maintaining IS. A 49 year-old Caucasian male developed progressive allograft failure nine years after living-donor renal transplantation. Hemodialysis was initiated via tunneled dialysis catheter(TDC) and IS was gradually withdrawn. Two weeksafter IS withdrawal he developed a febrile illness, which necessitate removal of the TDC and conversion to PD. He was maintained on small dose of tacrolimus(1 mg/d) and prednisone(5 mg/d). Currently(1 year later) he is doing exceedingly well on cycler-assisted PD. Residual urine output ranges between 600-1200 m L/d. Total weekly Kt/V achieved 1.82. RRF remained well preserved in this patient with failed renal allograft with minimal immunosuppressive therapy. This strategy will need further study in well-defined cohorts of PD patients with failed allografts and residual RRF to determine efficacy and safety. | Nadear Elmahi éva Csongrádi Kenneth Kokko Jack R Lewin Jamie Davison Tibor Fülp | 2013 | World Journal of Transplantation2013,3,2: | 5 |
| 3 | System Studies on CO2 Abatement From Power Plant 显示文摘 | Goldthorpe S H Cross P J I Davison J E | 1992 | Energy Convers Mgmt1992,33,58: | 1 |
| 4 | Stability of interfacial waves in aluminum reduction cell显示文摘 | L1NDSAY R I DAVISON P A | 1998 | Journal of Fluid Mechanics1998,362,: | 1 |
| 5 | The family Parvoviridae显示文摘 | Cotmore S F Agbandje-McKenna M Chiorini J A Mukha D V Pintel D J Qiu J Soderlund-Venermo M Tattersall P Tijssen P Gatherer D Davison A J | 2014 | Arch Virol2014,159,5: | 1 |
| 6 | Rotational Stiffness Characteristics of Steel Beam-to-column Connections显示文摘 | Davison J B Kirby P A Nethercot D A | 1987 | J of Construct Steel Research1987,,8: | 1 |
| 7 | Tissue expander infections in children:look beyond the expander pocket显示文摘 | DAVISON S P MANDERS E K | 1999 | Ann Plast Surg1999,43,5: | 1 |
| 8 | Stereotactic radiosurgery:the patient's experience显示文摘 | Menkes D B Davison M P Costello S A | | 0,,11: | 1 |
| 9 | Overexpression of beta-carotene hydroxylase enhances stress tolerance in Arabidopsis 显示文摘 | Davison P A Hunter C N Horton P | 2002 | Nature2002,418,: | 1 |
| 10 | The third-person effect in communieation显示文摘 | W P Davison | 1983 | Public Opinion Quarterly1983,47,: | 1 |
| 11 | Active signaling by HER-2/neu in a subpopulation of HER-2/neu-overexpressing ductal carcinoma in situ: clinicopathological correlates显示文摘 | Di Giovanna NIP Chu P Davison TL | 2002 | Cancer Res2002,62,22: | 1 |
| 12 | Succinic acid adsorption from fermentation broth and regeneration显示文摘 | DAVISON B H NGHIEM N P RICHARDSON G L | | Applied Biochemistry and Biotechnology-Part A Enzyme Engineering and Biotechnology0,114,123: | 1 |
| 13 | Experimental analysis and modeling of limit cycles in a dynamic wind tunnel rig显示文摘 | DAVISON P M LOWENBERG M H | 2003 | Journal of Aircraft2003,40,4: | 1 |
| 14 | Production of succinic acid by Anaerobiospirillum succiniciproducens显示文摘 | Nghiem N P Davison B H Suttle B E | 1997 | Applied Biochemistry andBiotechnology1997,63,5: | 1 |
| 15 | Active signaling by HER-2/neu in a subpopulation of HER-2/neu-overexpressing ductal carcinoma in situ:clinicopathological correlates显示文摘 | Digiovanna MP Chu P Davison TL | 2002 | Cancer Res2002,62,22: | 1 |
| 16 | Differential cytokine responses following Marek's disease virus infection of chickens differing in resistance to Marek's disease显示文摘 | KAISER P UNDERWOOD G DAVISON F | 2002 | J Virol2002,77,1: | 1 |
| 17 | Kinetics of metal exchange be- tween solids and solutions in sediments and soils interpreted from DGT measured fluxes显示文摘 | Harper M P Davison W Zhang H | 1998 | Geochimicaet Cosmochimica Acta1998,62,16: | 1 |
| 18 | Production of succinic acid by Anaerobiospirillum succiniciproducens显示文摘 | Nghiem N P Davison B H Suttle B E | 1997 | Appl Biochem Biotech1997,63,5: | 1 |
| 19 | Rotational stiffness characteristics of steel beam-to-column connections 显示文摘 | Davison J B Kirby P A Nethercot D A | 1987 | Journal of Constructional Steel Research1987,8,1: | 1 |
| 20 | Monitoring individual morphological changes over time in ovariectomized rats by in vivo micro-computed tomography显示文摘 | Boyd SK Davison P Muller R | | 0,,: | 1 |