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| 1 | Differentiation profile of brain tumor stem cells:a comparative study with neural stem cells显示文摘大脑肿瘤干细胞(BTSC ) 的区别侧面的理解,在肿瘤房间人口之中的关键的,将通过有神经干细胞(NSC ) 的比较借卓见进 glioma 的起源并且最终产出新途径与这难处理的疾病作斗争。这里,我们从外科的 glioma 标本的有教养、净化的 BTSC 和 NSCsfrom 人的胎儿的大脑织物,并且进一步分析了他们的细胞的生物行为,他们的特别区别性质。是期望,区分进成熟神经显型的 NSC。然而, BTSC 展出了的 Inthe 一样的区别状况区分了差别。词法上,房间变得变平并且属于第一个星期,但是逐渐地此后聚集了并且改过漂浮的肿瘤范围。在相应时期期间,无差别的房间标记 CD133 和巢在的表示率在 BTSC 不停地减少,但是 1 个星期以后,他们重获上升趋势。有趣地,区分的房间标记 GFAP 和 beta-tubulinIIIshowed 表示变化逆到无差别的房间标记的。总起来说, BTSCswere 揭示了拥有一个能力抵抗区别,它实际上代表 glioma 的恶意的行为。 | Quan Bin Zhang Xiao Yan Ji Qiang Huang Jun Dong Yu De Zhu Qing Lan | 2006 | Cell Research2006，16，12： | 34 |
| 2 | THE STRUCTURE OF ARMILLARIZIN,A NEW PROTOILLUDANE SESQUITERPENOID AROMATIC ESTER FROM ARMILLARIA MELLEA(VAHL.EX FR)QUEL.显示文摘A new protoilludane sesquiterpenoid aromatic ester,named armillarizin(1)has been isolated from the artificially cultured mycelium of Armillaria me-llea(Vahl.ex Fr)Quel.(Tricholomataceae).Its structure was deduced on the ba-sis of spectral analyses.The relative configuration was established from thenuclear Overhauser effects and from the values of ~1H-~1H coupling constants. | Jun Shan YANG Ya Lun SU Yu Lan WANG Xiao Zhang FENG De Quan YU Xiao Tian LIANG Institute of Materia Medica,Chinese Academy of Medical Sciences,Beijing,100050 | 1990 | Chinese Chemical Letters1990，1，2： | 8 |
| 3 | Stereoselective Addition of Organotitanium and Grignard Reagents to 3,5-O-isopropylidene-L-glucurono-γ-lactone显示文摘Substituted PhMgX and PhTi(OCHMe2)4MgX react with 3,5-O-isopropylidene-L-glucurono-γ-lactone 4 to give tetrads 5a-e and its stereoisomers 6a-e Tetrads 5a-e are the important intermediates in the synthesis of howiinol Al and its derivatives. The stereoselectivities of substituted PhTi(OCHMe2)4Mg (5a-e:6a-e ratio, 68-72:32-28) were better than those of substituted PhMgX(33-64:67-36) in the reaction. The effects of different substitUted groups and positions (p-Me, m-Me, o-MeO, p-Cl) of the phenyl ring on their stereoselectivies were not significant. | Hong CHEN Shao Yi SUN and De Quan YU(Institute of Meteria Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050) | 1998 | Chinese Chemical Letters1998，9，10： | 5 |
| 4 | A New Isoprenylated flavonol from the Leaves of Broussonetia kazinoki显示文摘A new isoprenylated flavonol, named broussonol A (1) was isolated from the leaves of Broussonetia kazinoki Sieb. The structure of broussonol A was characterized by chemical and spectral methods. | Pei Cheng ZHANG, Si WANG, Ying Hong WANG, Ruo Yun CHEN, De Quan YU* Institute of Materia Medica, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100050 | 2001 | Chinese Chemical Letters2001，12，2： | 5 |
| 5 | Three New Compounds from Forsythia Suspensa (Thunb.) Vahl显示文摘Three new compounds, suspenolic acid (1), forsythenside A (2), and forsythenside B (3) have been isolated from the fruits of Forsythia suspensa. Their smictures were elucidated by special methods including IR, 1H- and 13C-NMR, DEPT, 1H-1H COSY, 1H-13C COSY, NOE difference, HMBC, FABMS, CIMS, and chemical reactions. | Dong Sheng MING De Quan YU Shi Shan YU (Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050) | 1998 | Chinese Chemical Letters1998，9，1： | 5 |
| 6 | STRUCTURE ELUCIDATION OF LIGUSTILONE FROM LIGUSTICUM SINENSIS OLIV显示文摘STRUCTUREELUCIDATIONOFLIGUSTILONEFROMLIGUSTICUMSINENSISOLIV￥DeQuanYU;RuoYunCHEN;andFengZhiXIE.(InstituteofMateriaMedica,Chine... | De Quan YU Ruo Yun CHEN and Feng Zhi XIE.(Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing,100050) | 1995 | Chinese Chemical Letters1995，6，5： | 4 |
| 7 | A NEW DITERPENE LACTONE FROM TRIPTERYGIUM WILFORDII显示文摘A new diterpene lactone with an ent--kaurane skeleton, named antriptolactone(1)was isolated from the roots of Tripterygium wilfordii cellected in Anhui province. Its structurewas elucidated by spectral data and chemical transformtion. | De Quan YU Feng Zhi XIE Xiao Tian LIANG Institute of Mateia Medica, Chinese Academy of Medial Sciences, Beijeng, 100050 | 1992 | Chinese Chemical Letters1992，3，6： | 3 |
| 8 | A New Diels-Alder Type Adduct and a New Flavone from the Stem and Root Bark of Morus mongolica显示文摘A new Diels-Alder type adduct mongolicin G (1) and a new flavone 5′-(1′′, 1′′-dimethyl- allyl)-5,7,2′,4′-tetrahydroxyflavone (2) were isolated from the stem and root bark of Morus mongolica. Their structures were determined by spectroscopic analysis and chiroptical methods. | Jie KANG Ruo Yun CHEN De Quan YU | 2005 | Chinese Chemical Letters2005，16，11： | 3 |
| 9 | STUDIES ON THE STRURE OF LIGUSTIPHENOL FROM LIGUSTICUM SINENCE OLIV显示文摘STUDIES ON THE STRURE OF LIGUSTIPHENOL FROM LIGUSTICUM SINENCE OLIV.￣1)STUDIESONTHESTRUREOFLIGUSTIPHENOLFROMLIGUSTICUMSINENCE... | De Quan YU Feng Zhi XIE Ruo Yun CHEN and Yan He HUANG(Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050) | 1996 | Chinese Chemical Letters1996，7，8： | 2 |
| 10 | Synthesis and antitumor activity of a group ofdiosgenyl glycosides显示文摘Using orthogonal protection–deprotection glycosylation strategy, a series of diosgenyl glycosides with same of monosacchar- ides component but different in sequence were synthesized. The antitumor activity in vitro of synthesized diosgenyl glycosides was evaluated by standard MTT assay. It was observed that diosgenyl glycosides with a rhamnopyranosyl at C20 of glucopyranosyl residue show potent antitumor activity in vitro. | Shu Jie Hou Chuan Chun Zou Liang Zhou Peng Xu De Quan Yu Ping Sheng Lei | 2007 | Chinese Chemical Letters2007，18，7： | 2 |
| 11 | CD8 + T Cells That Produce Interleukin-17 Regulate Myeloid-Derived Suppressor Cells and Are Associated With Survival Time of Patients With Gastric Cancer显示文摘 | Yuan Zhuang Liu–Sheng Peng Yong–Liang Zhao Yun Shi Xu–Hu Mao Weisan Chen Ken C. Pang Xiao–Fei Liu Tao Liu Jin–Yu Zhang Hao Zeng Kai–Yun Liu Gang Guo Wen–De Tong Yan Shi Bin Tang Na Li Shu Yu Ping Luo Wei–Jun Zhang Dong–Shui Lu Pei–Wu Yu Quan–Ming Zou | 2012 | Gastroenterology2012，，4： | 2 |
| 12 | Alkaloids from the Roots of Saccopetalum prolificum显示文摘A new, alkaloid. named prolilfine (1), was isolated along with four known alkaloids. liriodenine (2). 6-hydroxyonychine (3). isooncodine (4) and discretamine (5) from the roots of Saccopetalum prolificum. The structure of I was elucidated on the basis of spectroscopic and chemical methods. | Ming Lei WANG Jiang DU Ruo Yun CHEN De Quan YU (Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050) | 2000 | Chinese Chemical Letters2000，11，2： | 2 |
| 13 | A NEW SESQUITERPENE FROM CHRYSANTHEMUM INDICUM显示文摘A new sesquiterpene with an eudesmane skeleton,named Chrysantherol wasisolated from the flowers of Chrysanthemum indicum.Its structure was elucidated as 1 mainly by theanalysis of spectral data. | De Quan YU Feng Zhi XIE Institute of Materia Medica,Chinese Academy of Medical Sciences,Beijing,100050 | 1993 | Chinese Chemical Letters1993，4，10： | 2 |
| 14 | Two new diterpenoids from Suregada glomerulata(Blume) Baill显示文摘二新 diterpenoids, 3,4,18-cyclopropa-ent-abieta-8 (14 ) , 13 (15 )-dien-16,12-olide (1 ) 和 3-oxojolkinolide B (2 ) ,从 Suregada glomerulata (布鲁坶) 的根被孤立 Baill。他们的结构被分光镜的证据决定。加重 2 显示出的中等 cytotoxicity。 | Ren Yi Yan Ruo Yun Chen De Quan Yu | 2011 | Chinese Chemical Letters2011，22，5： | 1 |
| 15 | Lignan and acetylenic glycosides from Aster auriculatus 显示文摘 | Wang Chang Zeng Yu De Quan | 1998 | Phytochemistry1998，48，4： | 1 |
| 16 | Calamistrin E, the First Annonaceous Acetogenin with Double Bond in Aliphatic Chain from Genus Uvaria显示文摘Calamistrin E. the first Annonaceous acetogenin with C=C bond in the aliphatic chain from the genus Uvaria was isolated from U calamistrata. Its structure including relative and absolute configurations was determined by chemical derivation and spectral analysis. | Guang Xiong ZHOU Ruo Yun CHEN Yan Jun ZHANG De Quan YU (Institute of Materia Medica. Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050) | 2000 | Chinese Chemical Letters2000，11，4： | 1 |
| 17 | Synthesis of (+) 8-O-Cinnamyl-p-chlorogoniotriol and its Analogues显示文摘(+) 8-O-Cinnamyl-p-chlorogoniotriol (p-chlorohowjinol A) and its analogues have beensynthesized in nine steps from a-D-glucoheptonic-r-lactone. Pharmacological tests showed thatmost of the compounds possessed antitumor activities toward tumor cell in | Hong CHEN Long En ZHOU Yan Jun ZHANG De Quan YU(Institute of Meteria Medica Chinese Academy of Medical Sciences &Peking Union Medical College. Beijing 100050) | 1999 | Chinese Chemical Letters1999，10，6： | 1 |
| 18 | A Novel Dihydroflavone from the Roots of Uvaria Macrophylla显示文摘A new dihydroflavone (1), named macrophyllol A, was isolated from the roots of Uvaria macrophylla. Its structure was elucidated on the basis of spectroscopic evidence. | Si WANG, Pei Cheng ZHANG, Ruo Yun CHEN, Ying Hong WANG, Wen Yi HE, De Quan YU* Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050 | 2002 | Chinese Chemical Letters2002，13，9： | 1 |
| 19 | Cracking causing cyclic instability of cathode material 显示文摘 | Wang De - yu Wu Xiao - dong Chen Li -quan | 2005 | J Power Sources2005，140，： | 1 |
| 20 | A new glycoside from the leaves of Neoalsomitra integrifoliola显示文摘新 ionone glycoside (6R,9R )-blumenyl 伪 -l-rhamnopyranosyl-(1 鈫 ? 6 )- 尾 -d-gluco-pyranoside (1 ) ,和新自然产品 2-methoxyl-4-trans-propenyl-phenol 伪 -l-rhamnopyranosyl-(1 鈫 ? 6 )- 尾 -d-glucopyranoside (2 ) ,从 Neoalsomitra integrifoliola 的叶子被孤立。他们的结构被化学、光谱的分析阐明。化合物 1 显示出弱反煽动性、低级的抗氧化剂活动。 | Dong Min Su Jing Qu You Cai Hu Shi Shan Yu Wen Zhao Tang Yun Bao Liu Shuang Gang Ma De Quan Yu | 2008 | Chinese Chemical Letters2008，19，7： | 1 |
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