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| 1 | Mesenchymal stem cells: Molecular characteristics and clinical applications显示文摘Mesenchymal stem cells (MSCs) are non-hematopoietic stem cells with the capacity to differentiate into tissues of both mesenchymal and non-mesenchymal origin. MSCs can differentiate into osteoblastic, chondrogenic, and adipogenic lineages, although recent studies have demonstrated that MSCs are also able to differentiate into other lineages, including neuronal and cardiomyogenic lineages. Since their original isolation from the bone marrow, MSCs have been successfully harvested from many other tissues. Their ease of isolation and ex vivo expansion combined with their immunoprivileged nature has made these cells popular candidates for stem cell therapies. These cells have the potential to alter disease pathophysiology through many modalities including cytokine secretion, capacity to differentiate along various lineages, immune modulation and direct cell-cell interaction with diseased tissue. Here we first review basic features of MSC biology including MSC characteristics in culture, homing mechanisms, differentiation capabilities and immune modulation. We then highlight some in vivo and clinical evidence supporting the therapeutic roles of MSCs and their uses in orthopedic, autoimmune, and ischemic disorders. | Farbod Rastegar Deana Shenaq Eric R Wagner Stephanie H Kim Russell R Reid Hue H Luu Rex C Haydon | 2010 | World Journal of Stem Cells2010，2，4： | 35 |
| 2 | 标准·方案·指南——2014年美国癌症学会最新宫颈癌筛查指南及筛查中存在的问题显示文摘美国癌症学会(ACS)每年都会发布有关癌症早期检测、癌症筛查率数据与趋势报告及相关问题的指南,并会持续关注可能需要在癌症筛查指南中做出相应改变与更新的医学科学文献中出现的新证据以及需要传达给临床工作者与公众的筛查相关信息。在制定新指南的过程中,ACS至少每5年对指南更新1次,如有重要新证据出现,则更新间隔时间会更短。本期就2014年ACS关于宫颈癌筛查的最新指南报道如下。 | Robert A Smith Deana Manassaram-Baptiste Durado Brooks Vilma Cokkinides Mary Doroshenk Debbie Saslow Richard C Wender Otis W Brawley 王静 | 2014 | 中国全科医学2014，17，27： | 16 |
| 3 | Cancer screening in the United States, 2014: A review of current American Cancer Society guidelines and current issues in cancer screening显示文摘 | Robert A. Smith Deana Manassaram-Baptiste Durado Brooks Vilma Cokkinides Mary Doroshenk Debbie Saslow Richard C. Wender Otis W. Brawley | 2014 | CA A Cancer Journal for Clinicians2014，，： | 2 |
| 4 | The effect of purified extract of Fagopyrum esculentum(buckwheat) on protein kinases involved in signal transduction pathways显示文摘 | Samel D Deana D A De Witte P | 1996 | Planta Med1996，62，2： | 1 |
| 5 | Experimental and probabilistic analysis of distal femoral periprosthetic fracture: a comparison of locking plate and intramedullary nail fixation. Part B: probabilistic investigation显示文摘 | Christina Salas Deana Mercer Thomas A. DeCoster Mahmoud M. Reda Taha | 2011 | Computer Methods in Biomechanics and Biomedical Engineering2011，，2： | 1 |
| 6 | The effect of purified extract of Fagopyrum esculentum(buckwheat) on protein kinases involved in signal transduction pathways显示文摘 | Samel D Deana D A De Witte P | 1996 | Planta Med1996，62，2： | 1 |
| 7 | A potential immune escape mechanism by melanoma ceils through the activation of chemokine -induced T cell death 显示文摘 | Mellado M Deana AM Moreno MC | 2001 | Cur Biol : CB2001，11，9： | 1 |
| 8 | Reversible ischemic colitis in young women:Association with oral contraceptive use显示文摘 | Deana DG Dean PJ | 1995 | Am J Surg Pathol1995，19，4： | 1 |
| 9 | Bridging time and distance:continuingeducation needs for rural health care providers显示文摘 | Deana M | 2001 | Home Health Care Management Practice2001，12，： | 1 |
| 10 | Some approaches to the synthesis of sulbactam显示文摘 | Suren husinec Deana Dragovic | 1989 | Cocc Czec Chem Comm1989，54，： | 1 |
| 11 | Carbapenems resistance of Acinetobacter spp strains isolated from wound swabs during 2009-2010显示文摘 | Medi Deana Mihajlovic-Ukropina Mira Gusman Vera | 2012 | Medicinski Pregled2012，64，11： | 1 |
| 12 | Visual prod- uct evaluation: exploring users' emotional relationships with prod- uets显示文摘 | Deana McDonagh Anne Bruseberg Cheryl Haslam | 2002 | Applied Ergonomics2002，33，： | 1 |
| 13 | Green tea epigallocatechin-3-gallate inhibits platelet signalling pathways triggered by both proteolytic and non-proteolytic agonists显示文摘 | Turetta L Donella-Deana A | 2003 | Thromb Haemost2003，89，5： | 1 |
| 14 | Visual product evaluation:exploring users'emotional relationships with products显示文摘 | DEANA M ANNE B CHERY H | 2002 | Applied Ergonomics2002，，33： | 1 |
| 15 | Silent mutations in the Escherichia coli ompA leader peptide region strongly affect transcription and translation in vivo 显示文摘 | Deana A Ehrlich R Reiss C | 1998 | Nucleic Acids Research1998，26，20： | 1 |
| 16 | Color differences of ca- nines and incisors in a comparative long-term clinical trim of three bleaching systems显示文摘 | Wetter NU Branco EP Deana AM | 2009 | Lasers Med Sci2009，24，6： | 1 |
| 17 | A seasonal staffing model显示文摘 | Lee S Deana N | 1996 | Lippinoff Raven1996，26，4： | 1 |
| 18 | Qualitative network models and genome-wide expression data define carbon/nitrogen-responsive molecular machines in Arabidopsis显示文摘 | Gutierrez R A LejayLV DeanA | 2007 | Genome Biol2007，8，： | 1 |
| 19 | A clinical ladder program based on carp- ers fundamental patterns of knowing in nursing显示文摘 | Lee AS Deana N Leah G | 2003 | JONA2003，33，3： | 1 |
| 20 | Energy absorption during projectile perforation of lightweight sandwich panels with metallic fibre cores显示文摘 | Deana J S -Fallah A Brown P M | 2011 | 93(3) : 1089 -10952011，93，3： | 1 |
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