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| 1 | Obesity and cardiometabolic disease risk factors among US adolescents with disabilities显示文摘AIM: To generate prevalence estimates of weight status and cardiometabolic disease risk factors among adolescents with and without disabilities.METHODS: Analysis of the 1999-2010 National Health and Nutrition Examination Survey data was conducted among 12-18 years old with(n = 256) and without disabilities(n = 5020). Mean values of waist circumference, fasting glucose, high-density-lipoprotein cholesterol, triglycerides, systolic and diastolic blood pressure and metabolic syndrome(Met S, ≥ 3 risk factors present) were examined by the following standardized body mass index(BMI) categories for those with and without disabilities; overweight(BMI ≥ 85th- < 95 th percentile for age and sex), obesity(BMI ≥ 95 th percentile) and severe obesity(BMI ≥35 kg/m2). Linear regression models were fit with each cardiometabolic disease risk factor independently as continuous outcomes to show relationships with disability status. RESULTS: Adolescents with disabilities were significantlymore likely to be overweight(49.3%), obese(27.6%) and severely obese(12%) vs their peers without disabilities(33.1%, 17.5% and 3.6%, respectively, P ≤ 0.01 for all). A higher proportion of overweight, obese and severely obese children with disabilities had abnormal SBP, fasting lipids and glucose as well as Met S(18.9% of overweight, 32.3% of obese, 55% of severely obese) vs their peers without disabilities(9.7%, 16.8%, 36.3%, respectively). US adolescents with disabilities are over three times as likely to have Met S(OR = 3.45, 95%CI: 1.08-10.99, P = 0.03) vs their peers with no disabilities.CONCLUSION: Results show that adolescents with disabilities are disproportionately affected by obesity and poor cardiometabolic health vs their peers with no disabilities. Health care professionals should monitor the cardiometabolic health of adolescents with disabilities. | Sarah E Messiah Denise C Vidot Gabriel Somarriba Kanathy Haney Semra Aytur Ruby A Natale Jeffrey P Brosco Kristopher L Arheart | 2015 | World Journal of Diabetes2015，6，1： | 2 |
| 2 | Early age-related changesin episodic memory retrieval as revealed by event-related potentials显示文摘 | Guillaume C Clochon P Denise P | 2009 | Neuroreport2009，20，2： | 1 |
| 3 | Isolation and clonal analysis of human epidermal keratinocyte stem cells in long - term culture显示文摘 | Sandra P Denise C Daniela C | 2003 | Stem Cells2003，21，： | 1 |
| 4 | Academic stress differentially influences perceived stress,salivary cortisol,and immunoglobulin-A in undergraduate students显示文摘 | Murphy L Denis R Ward C P | | 0，，4： | 1 |
| 5 | Motion sickness induced by otolith stimulation is correlated with otolith-induced eye movements显示文摘 | Ventre-Dominey J Luyat M Denise P Darlot C | 2008 | Neuroscience2008，155，： | 1 |
| 6 | Hydrogenation of Carbon Dioxide Catalyzed by Ruthenium Trimethylphosphine Complexes: The Accelerating Effect of Certain Alcohols and Amines 显示文摘 | Munshi P Denise M A Linehan J C | 2002 | J Am Chem Soc2002，124，： | 1 |
| 7 | Hydrogenation of carbon dioxide catalyzed by ruthenium trimethylphos- phine complexes : the accelerating effect of certain alcohols and amines显示文摘 | Munshi P Denise M A Linehan J C | 2002 | J Am Chem Soc2002，24，27： | 1 |
| 8 | Prenatal ultra- sound and fetal MRI : the comparative value of each modality in prenatal diagnosis显示文摘 | DENISE P BRUGGER P C DIETER B | 2008 | Eur J Radiol2008，68，2： | 1 |
| 9 | Motion sicknessinduced by otolith stimulation is correlated with otolith- induced eyemovements显示文摘 | Ventre-Dominey J Luyat M Denise P Darlot C | 2008 | Neuroscience2008，，： | 1 |
| 10 | The lethality of Euphorbia conspicua to adults of Biomphalarla glabrata, cercaria of Schistosoma mansoni and larvae of Artemia salina 显示文摘 | Aldenir F dos Santos Denise P L de Azevedo Rosalina da C dos Santos Mata | 2007 | Bioresour Technol2007，98，1： | 1 |
| 11 | Localized reduction of atherosclerosis in von Willebrand factor-deficient mice显示文摘 | Methia N André P Denis C V | | 0，，05： | 1 |
| 12 | Mo- tion sickness induced by otolith stimulation is correla- ted with otolith-induced eye movements 显示文摘 | Ventre-Dominey J Luyat M Denise P Darlot C | 2008 | Neuro- science2008，155，： | 1 |
| 13 | First-line latanoprost therapy in ocular hypertension or open-angle glaucoma patients:a 3-month efficacy analysis stratified by initial intraocular pressure显示文摘 | Denis P Baudouin C Bron A | | 0，，： | 1 |
| 14 | Hydrocodensation of Carbon Dioxide:Ⅳ显示文摘 | Denise B Sneeden R P A Haman C | 1982 | J Molec Catal1982，17，3： | 1 |
| 15 | Predictors of electronic bulletin board system use in older adults 显示文摘 | Kelley L Roger W M Denise C P | 1999 | Educational Gerontology1999，25，1： | 1 |
| 16 | Expression from second-generation feline immunodeficiency virus vectors is impaired in human hematopoietic cells显示文摘 | Mary A P Scott S C Denise A C | 2002 | Molecular Therapy2002，6，5： | 1 |
| 17 | Isolation and clonal analy- sis of human epidermal keratinocyte stem cell in long term cul ture显示文摘 | Sandra P Denise C Daniela C | 2003 | Stem Cell2003，21，： | 1 |
| 18 | Is cognitive change related to hypothyroidism reversible with replacement therapy显示文摘 | Capet C Jego A Denis P | | 0，，8： | 1 |
| 19 | CD40L stabilizes arterial thrombi by a beta-3 integrin dependent mechanism显示文摘 | Andre P Prasad K S Denis C V | | 0，，03： | 1 |
| 20 | Effect of soy protein supplementation in patients with chronic hepatitis C:A randomized clinical trial显示文摘AIM:To evaluate the effects of soy supplementation on insulin resistance,fatty liver and alanine aminotransferase(ALT) levels in non-diabetic patients with chronic hepatitis C(CHC).METHODS:In a prospective,randomized and singleblinded clinical trial,we compared patients with CHC who had casein as a supplement(n = 80)(control group),with patients who consumed a soy supplement diet(n = 80) [intervention group(IG)].Both groups received 32 g/d of protein for 12 wk.RESULTS:Patients' baseline features showed that 48.1% were overweight,43.7% had abdominal fat accumulation,34.7% had hepatic steatosis and 36.3% had an homeostasis model assessment index of insulin resistance(HOMA-IR) ≥ 3.0.Descriptive analysis showed that protein supplementation diet reduced hepatic steatosis in both groups;however,significant reductions in ALT levels occurred in the soy group.Multiple regression modeling indicated that in the presence of severe fibrosis(F3/F4),g glutamyl transferase elevation and high density lipoprotein(HDL) reduction,the intervention group had 75% less chance of developing hepatic steatosis(OR= 0.25;95% CI:0.06-0.82) and 55% less chance of presenting with an ALT level ≥ 1.5 × the upper limit of normal(ULN)(OR = 0.45,95% CI:0.22-0.89).Soy treatment did not have any effect on insulin resistance(OR = 1.92;95% CI:0.80-4.83),which might be attributed to the fact that the HOMAIR values at baseline in most of our patients were in the normal range.Advanced hepatic fibrosis,an ALT level > 1.5 × ULN and visceral fat were predictors of an HOMA-IR ≥ 3.The IG group had a reduced risk of an ALT level > 1.5 × ULN.An HOMA-IR ≥ 3.0 and HDL < 35 mg/dL were also risk factors for increased ALT.CONCLUSION:Soy supplementation decreased ALT levels and thus may improve liver inflammation in hepatitis C virus(HCV) patients;it also reduced hepatic steatosis in a subgroup of patients but did not change insulin resistance.It should be considered in the nutritional care of HCV patients. | Lucivalda PM Oliveira Rosangela P de Jesus Ramona SSB Boulhosa Carlos Mauricio C Mendes Maria Cecilia Gnoatto Denise C Lemaire Maria Betania P Toralles Lourianne N Cavalcante Andre C Lyra Luiz GC Lyra | 2012 | World Journal of Gastroenterology2012，18，18： | 1 |
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