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50篇 您的检索式：作者名="Denner J"

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	题名	作者	年代	出处	被引量
1	Feyn Arts: Computer Algebraic Generation of Feynman Graphs and Amplitudes 显示文摘	Kublbeck J Bohm M Denner A	1990	Computer Physics Communications1990，60，：	1
2	Porcine endogenous retroviruses inhibit human immune cell function: risk for xenotransplantation显示文摘	Tacke S J Kurth R Denner J	2000	Virology2000，268，1：	1
3	Inhibition of porcine endogenous retroviruses by RNA interference: increasing the safety of xenotransplantation 显示文摘	Karlas A Kurth R Denner J	2004	Virology2004，325，1：	1
4	Productive infection of human primary cells and cell lines with porcine endogenous retroviruses显示文摘	Specke V Rubant S Denner J	2001	Virology2001，285，2：	1
5	Chemotaxonomic characterization of Sphingomonas显示文摘	BUSSE H J KAMPFER P DENNER E	1999	J of Ind Microbiol and Biotechnol1999，23，45：	1
6	L-glutamate decarboxylase from brain显示文摘	WU J Y Denner L	1985	Methods Enzymol1985，113，：	1
7	Directed engineering of umbilical cord blood stem cells toproduce Cpeptide and insulin显示文摘	Denner L Bodenburg Y Zhao J G	2007	Cell Proliferation2007，40，：	1
8	Cognitive enhancement with rosiglitazone links the hippoeampal PPARγ and ERK MAPK signaling pathways 显示文摘	Denner L A Rodriguez-Rivera J Haidaeher S J	2012	J Neurosci2012，32，16：	1
9	Targeted proteomics for biomarker discovery and validation of hepatocellular carcinoma in hepatitis C infected patients显示文摘Hepatocellular carcinoma(HCC)-related mortality is high because early detection modalities are hampered by inaccuracy,expense and inherent procedural risks.Thus there is an urgent need for minimally invasive,highly specific and sensitive biomarkers that enable earlydisease detection when therapeutic intervention remains practical. Successful therapeutic intervention is predicated on the ability to detect the cancer early. Similar unmet medical needs abound in most fields of medicine and require novel methodological approaches. Proteomic profiling of body fluids presents a sensitive diagnostic tool for early cancer detection. Here we describe such a strategy of comparative proteomics to identify potential serum-based biomarkers to distinguish high-risk chronic hepatitis C virus infected patients from HCC patients. In order to compensate for the extraordinary dynamic range in serum proteins,enrichment methods that compress the dynamic range without surrendering proteome complexity can help minimize the problems associated with many depletion methods. The enriched serum can be resolved using 2D-difference in-gel electrophoresis and the spots showing statistically significant changes selected for identification by liquid chromatographytandem mass spectrometry. Subsequent quantitative verification and validation of these candidate biomarkers represent an obligatory and rate-limiting process that is greatly enabled by selected reaction monitoring(SRM). SRM is a tandem mass spectrometry method suitable for identification and quantitation of target peptides within complex mixtures independent on peptidespecific antibodies. Ultimately,multiplexed SRM and dynamic multiple reaction monitoring can be utilized for the simultaneous analysis of a biomarker panel derived from support vector machine learning approaches,which allows monitoring a specific disease state such as early HCC. Overall,this approach yields high probability biomarkers for clinical validation in large patient cohorts and represents a strategy extensible to many diseases.	Gul M Mustafa Denner Larry John R Petersen Cornelis J Elferink	2015	World Journal of Hepatology2015，7，10：	1
10	Cognitive enhancement with rosiglitazone links the hippocampal PPARγ and ERK MAPK signaling pathways显示文摘	Denner LA Rodriguez-Rivera J Haidacher SJ	2012	J Neurosci2012，32，16：	1
11	Double blockade of cell cycle at G1-S transition and M phase by 3- ied oacetamido benzoyl ethylester, a new type of tubulin ligand显示文摘	Jiang J D Denner L Ling Y H	2002	Cancer Res2002，62，21：	1
12	Cognitive en- hancement with rosiglitazone links the hippocampal PPAR7 and ERK MAPK signaling pathways显示文摘	Denner LA Rodriguez-Rivera J Haidacher S J	2012	J Neurosei2012，32，16：	1
13	Computational thinking for youth in practice显示文摘	Lee I Martin F Denner J	2011	ACM Inroads2011，2，1：	1
14	Productive infection of human primary cells and cell lines with porcine endogenous retroviruses显示文摘	Specke V Rubant S Denner J	2001	Virology2001，285，2：	1
15	Virus safety in xenotransplantation:first exploratory in vivo studies in small laboratory animals and non-human primates显示文摘	Schuurman H J Plesker R Coulibaly C Ozel M Langford G Kurth R Denner J	2002	Transpl Immunol2002，9，24：	1
16	Treatment of Ebola virus infections with inhibitors of TLR4 显示文摘	Denner J	2015	Med Hypotheses2015，85，3：	1
17	Porcine endogenous retroviruses inhibit human immune cell function:risk for xenotransplantation显示文摘	Tacke S J Kurth R Denner J	2000	Virology2000，268，：	1
18	Rosiglitazone reversal of Tg2576 cognitive deficits is independent of peripheral gluco-regulatory status 显示文摘	Rodriguez-Rivera J Denner L Dineley KT	2011	Behav Brain Res2011，216，1：	1
19	Flow of He Ⅱ through porous plugs 显示文摘	Denner H D Klipping G Merzel J	1978	Cryogenics1978，18，3：	1
20	The effect of zinc coatings on the formability of automotive sheet steels显示文摘	Meuleman D J Denner S G Cheng F L	1984	SAE Paper1984，，840370：	1

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