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| 1 | Current scenario of traditional medicines in management of diabetic foot ulcers:A review显示文摘Diabetic foot infections and diabetic foot ulcers(DFU)cause significant suffering and are often recurring.DFU have three important pathogenic factors,namely,microangiopathy causing local tissue anoxia,neuropathy making the foot prone to injuries from trivial trauma,and local tissue hyperglycaemia favouring infection and delaying the wound healing.DFU have been the leading cause for non-traumatic amputations of part or whole of the limb.Western medicines focus mainly on euglycaemia,antimicrobials,debridement and wound cover with grafts,and off-loading techniques.Advances in euglycaemic control,foot care and footwear,systemic antimicrobial therapy,and overall health care access and delivery,have resulted in an overall decrease in amputations.However,the process of wound care after adequate debridement remains a major cost burden globally,especially in developing nations.This process revolves around two basic concerns regarding control/eradication of local infection and promotion of faster healing in a chronic DFU without recurrence.Wound modulation with various dressings and techniques are often a costly affair.Some aspects of the topical therapy with modern/Western medicines are frequently not addressed.Cost of and compliance to these therapies are important as both the wounds and their treatment are“chronic.”Naturally occurring agents/medications from traditional medicine systems have been used frequently in different cultures and nations,though without adequate clinical base/relevance.Traditional Chinese medicine involves restoring yin-yang balance,regulating the‘chi’,and promoting local blood circulation.Traditional medicines from India have been emphasizing on‘naturally’available products to control wound infection and promote all the aspects of wound healing.There is one more group of chemicals which are not pharmaceutical agents but can create acidic milieu in the wound to satisfy the above-mentioned basic concerns.Various natural and plant derived products(e.g.,honey,aloe vera,oils,and calendula)and maggots are also used for wound healing purposes.We believe that patients with a chronic wound are so tired physically,emotionally,and financially that they usually accept native traditional medicine which has the same cultural base,belief,and faith.Many of these products have never been tested in accordance to“evidence-based medicine.”There are usually case reports and experience-based reports about these products.Recently,there have been some trials(in vitro and in vivo)to verify the claims of usage of traditional medicines in management of DFU.Such studies show that these natural products enhance the healing process by controlling infection,stimulating granulation tissue,antimicrobial action,promoting fibroblastic activity and collagen deposition,etc.In this review,we attempt to study and analyse the available literature on results of topical traditional medicines,which are usually advocated in the management of DFU.An integrated and‘holistic’approach of both modern and traditional medicine may be more acceptable to the patient,cost effective,and easy to administer and monitor.This may also nevertheless lead to further improvement in quality of life and decrease in the rates of amputations for DFU. | Abhijit S Rayate Basavraj S Nagoba Sachin S Mumbre Hardi B Mavani Ajay M Gavkare Advait S Deshpande | 2023 | World Journal of Diabetes2023，14，1： | 3 |
| 2 | Molecular and industrial aspects of glucose isomerase 显示文摘 | Bhosale S H Rao M B Deshpande V V | 1996 | Microbiol Reveiw1996，60，： | 1 |
| 3 | Fast RCS Computation over a Frequency Band Using Method of Moments in Conjunction with Asymptotic Waveform Evaluation Technique显示文摘 | Reddy C J Deshpande M D Cockrell C R | 1998 | IEEE Trans on Antennas and Propagation1998，46，8： | 1 |
| 4 | Reduced memory listless speck image compression 显示文摘 | LATTE M V AYACHIT N H DESHPANDE D K | 2006 | Digital Signal Processing: A Review Journal2006，16，6： | 1 |
| 5 | Direct conversion of cellulose/hemicellulose to ethanol by Neurospom crassa显示文摘 | Deshpande V Keskar S Mishra C & Rao M | 1985 | Enzyme Microb Technol1985，7，： | 1 |
| 6 | Item-based top-N Recommendation Algorithms显示文摘 | Deshpande M Karypis G | 2004 | ACM Transactionon Information Systems2004，22，1： | 1 |
| 7 | Experimental Studies on Bursting Pressure of Thin - walled Flow Formed Pressure Vessels 显示文摘 | RAJAN K M DESHPANDE U P NARASIMHAN K | 2002 | Journal of Materials Processing Technology2002，，： | 1 |
| 8 | UHF wind profiler observations of monsoon low level jet over Pune显示文摘 | JOSHI R R NARENDRA S DESHPANDE S M | 2006 | Indian Journal of Radio & Space physics2006，35，： | 1 |
| 9 | Experimen- tal reproduction of canine influenza virus H3N8 infection in young puppies显示文摘 | DESHPANDE M ABDELMAGID O TUBBS A | 2009 | Vet Ther2009，10，12： | 1 |
| 10 | Web usage mining:discovery and application of usage patterns from web data显示文摘 | Srivastava J Cooley R Deshpande M | 2000 | SIGKDD Explorations2000，1，2： | 1 |
| 11 | Extracapsular cataract surgery compared with manual small incision cataract surgery in community eye care setting in western India:a randomised controlled trial 显示文摘 | Gogatc P Deshpande M Wormald R | 2003 | Br J Ophthalmol2003，87，6： | 1 |
| 12 | Catalytic Vapor Phase Reduction of Nitrobenzene to Aniline in Fluidized Beds显示文摘 | Deshpande P K Kuloor N R | 1963 | Chemical Age of India1963，14，： | 1 |
| 13 | 8042-/ SnO2: Efficient, chemoselective, and reusable catalyst for acylation of alcohols, phenols, and amines at room temperature 显示文摘 | Satam J R Gawande M B Deshpande S S | 2007 | Synth Commun2007，37，17： | 1 |
| 14 | Management of pediatric pain with opioid analgesics 显示文摘 | Yaster M Deshpande JK | 1988 | J Pediatr1988，113，： | 1 |
| 15 | Web usage mining:Discovery and applications of usage patterns from web data显示文摘 | Srivastava J Cooley R Deshpander M | 2000 | SIGDD Explorations2000，，1： | 1 |
| 16 | Web usage mining: discovery and applications of us- age patterns from web data 显示文摘 | SRIVASTAVA J COOLEY R DESHPANDE M | 2000 | SlGKDD Explorer Ne- wsletter2000，1，2： | 1 |
| 17 | Antimitogenic effects of 13-agonists and PGE2 on airway smooth muscle are PKA dependent 显示文摘 | Yan H Deshpande D A Misior A M | 2011 | FASEB J2011，25，1： | 1 |
| 18 | Evaluation of Natural Essential Oils as Antifeedants against Spodoptera litura显示文摘 | SHARMA R N DESHPANDE S G JOSEPH M | 1990 | Indian Perfumer1990，34，3： | 1 |
| 19 | Op- posing effects of pigment epithelium-derived factor on breast cancer cell versus neuronal survival:implication for brain metastasis and metastasis-induced brain damage显示文摘 | Fitzgerald DP~Subramanian P Deshpande M | 2012 | Cancer Res2012，72，1： | 1 |
| 20 | Selective assay for endo-β-1,4-glucanases显示文摘 | Pettersson L G Eriksson K E | 1988 | Methods Enzymol1988，160，： | 1 |
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