维普中文期刊产品整合服务
1篇 您的检索式:作者名="Deter R.L."
    题名 作者 年代 出处 被引量
1宫内输血两次后大脑中动脉收缩期流速峰值与胎儿血红蛋白的关系显示文摘The middle cerebral artery peak systolic velocity (MCA- PSV) has been successfully used for timing the first 2 transfusions in fetuses at risk for anemia because of maternal red cell alloimmunization. The Abstract of this study was to assess whether the correlation between the MCA- PSV and fetal hemoglobin is maintained in fetuses that had undergone 2 previous intrauterine transfusions. Study design: Doppler measurement of MCA- PSV was performed before cordocentesis in 39 fetuses. The timing of the third transfusion was based on traditional criteria. The values of MCA- PSV and hemoglobin were expressed as multiples of the median (MoM). Anemia was defined as mild (hemoglobin < 0.84 MoM for a given gestational age, moderate (hemoglobin < 0.65 MoM), and severe (hemoglobin < 0.55 MoM). Regression analysis was used to assess the correlation between the MCA- PSV MoM and fetal hemoglobin MoM. Results: Gestational age at Doppler study ranged from 22 to 35 weeks. Six fetuses (15% ) had normal hemoglobin concentration; 21 (53% ) had mild anemia; 7 (20% ) had moderate anemia; and 5 (12% ) had severe anemia. There was a linear correlation between fetal hemoglobin (y) and the MCA- PSV (x): y = 1.185 - 0.341x. Conclusion: Previously, concerns have been expressed about the accuracy of Doppler prediction of anemia after previous transfusions. Our data suggest that there is a good correlation between the MCA- PSV and fetal hemoglobin in fetuses that have undergone 2 previous transfusions. Our findings expand the clinical situation in which Doppler can be used to monitor red cell alloimmunized pregnancies.Mari G. Zimmermann R. Moise Jr. K.J. Deter R.L. 高雪莲 2006世界核心医学期刊文摘(妇产科学分册)2006,2,1:1
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