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2篇 您的检索式:作者名="Dethlefs F"
    题名 作者 年代 出处 被引量
1Gas chromatography/mass spectrometry of 13 resin acids as their PFB esters 显示文摘Dethlefs F Gerbardtz K O Stan H J 1996Journal of Mass Spectrometry1996,31,:1
2Training stem cells for treatment of malignant brain tumors显示文摘The treatment of malignant brain tumors remains a challenge. Stem cell technology has been applied in the treatment of brain tumors largely because of the ability of some stem cells to infiltrate into regions within the brain where tumor cells migrate as shown in preclinical studies. However, not all of these efforts can translate in the effective treatment that improves the quality of life for pa-tients. Here, we perform a literature review to identify the problems in the field. Given the lack of efficacy of most stem cell-based agents used in the treatment of malignant brain tumors, we found that stem cell distribution(i.e., only a fraction of stem cells applied capable of targeting tumors) are among the limiting factors. We provide guidelines for potential improvements in stem cell distribution. Specifically, we use an engineered tissue graft platform that replicates the in vivo microenvironment, and provide our data to validate that this culture platform is viable for producing stem cells that have better stem cell distribution than with the Petri dish culture system.Shengwen Calvin Li Mustafa H Kabeer Long T Vu Vic Keschrumrus Hong Zhen Yin Brent A Dethlefs Jiang F Zhong John H Weiss William G Loudon 2014World Journal of Stem Cells2014,6,4:0
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