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| 1 | Celiac disease:Management of persistent symptoms in patients on a gluten-free diet显示文摘AIM:To investigate all patients referred to our center with non-responsive celiac disease (NRCD),to establish a cause for their continued symptoms.METHODS:We assessed all patients referred to our center with non-responsive celiac disease over an 18-mo period.These individuals were investigated to establish the eitiology of their continued symptoms.The patients were first seen in clinic where a thorough history and examination were performed with routine blood work including tissue transglutaminase antibody measurement.They were also referred to a specialist gastroenterology dietician to try to identift any lapses in the diet and sources of hidden gluten ingestion.A repeat small intestinal biopsy was also performed and compared to biopsies from the referring hospital where possible.Colonoscopy,lactulose hydrogen breath testing,pancreolauryl testing and computed tomography scan of the abdomen were undertaken if the symptoms persisted.Their clinical progress was followed over a minimum of 2 years.RESULTS:One hundred and twelve consecutive patients were referred with NRCD.Twelve were found not to have celiac disease (CD).Of the remaining 100 patients,45% were not adequately adhering to a strict gluten-free diet,with 24 (53%) found to be inadvertently ingesting gluten,and 21 (47%) admitting noncompliance.Microscopic colitis was diagnosed in 12% and small bowel bacterial overgrowth in 9%.Refractory CD was diagnosed in 9%.Three of these were diagnosed with intestinal lymphoma.After 2 years,78 patients remained well,eight had continuing symptoms,and four had died.CONCLUSION:In individuals with NRCD,a remediable cause can be found in 90%:with continued gluten ingestion as the leading cause.We propose an algorithm for investigation. | David H Dewar Suzanne C Donnelly Simon D McLaughlin Matthew W Johnson H Julia Ellis Paul J Ciclitira | 2012 | World Journal of Gastroenterology2012，18，12： | 2 |
| 2 | Evaluating the communication process between interpreter and visitor显示文摘 | Ryan C Dewar K | 1995 | Tourism management1995，16，4： | 1 |
| 3 | A root-shoot partitioning model based on carbon- nitrogen-water interaction and Munch phloem flow显示文摘 | Dewar R C | 1993 | Functional Ecology1993，7，3： | 1 |
| 4 | Increased understanding of nutrient immobilization in soil organic matter is critical for predicting the carbon sink strength of forest ecosystem over the next 100 years显示文摘 | Medlyn B E Dewar R C | 2001 | Tree Physiology2001，21，： | 1 |
| 5 | Jaagsiekte sheep ret- rovirus-specific immune responses induced by vaccination : a compar- ison of immunisation strategies 显示文摘 | Summers C Dewar P van der Molen R | 2006 | Vaccine2006，24，11： | 1 |
| 6 | Jaagsiekte sheep retrovirus-specific immune responses induced by vaccination: A comparison of immunisation strategies 显示文摘 | Summers C Dewar P | 2006 | Vaccine2006，，24： | 1 |
| 7 | The Correspondence Between the Resonance and Molecular Orbital Theory 显示文摘 | Dewar M J S Longuet-Higgins H C | 1952 | Proc Roy Soc1952，214，： | 1 |
| 8 | Acclimation of the respiration/photosynthesis ratio to temperature: insights from a model 显示文摘 | DEWAR R C MEDLYN B E MCMURTRIE R | 1999 | Global Change Biology1999，5，61： | 1 |
| 9 | A simple model of light and water use evaluated for Pinus radiata 显示文摘 | Dewar R C | 1997 | Tree Physiology1997，17，： | 1 |
| 10 | Systemic immune responses following infection with jaagsiekte sheep retrovirus and in the terminal stages of ovine pulmonary adenocarcinoma显示文摘 | Summers C Neill W Dewar P | 2002 | J Virol2002，83，： | 1 |
| 11 | Maximum entropy production and plant optimizationtheories显示文摘 | Dewar R C | 2010 | Philos Trans R Soc Lond B Biol Sci2010，365，1545： | 1 |
| 12 | Evaluation The Communication Process Between Interpretatier and Visitor显示文摘 | Ryan C Dewar K | 1995 | Tourism Management1995，16，4： | 1 |
| 13 | Learning from difference: The potentially transformating experience of community - university collaboration 显示文摘 | M &Isaac C | 1998 | Journal of Planning Education and Research1998，，1： | 1 |
| 14 | Maximum entropy production and the fluctuation theorem 显示文摘 | Dewar R C | 2005 | Journal of Physics A: Mathematical and General2005，38，： | 1 |
| 15 | Information theory explanation of the fluctuation theorem,maximum entropy production,and self-organized criticality in non-equilibrium stationary states 显示文摘 | Dewar R C | | Journal of Physics Application0，36，： | 1 |
| 16 | Emergency department nurse-based outpatient diagnosis of DVT using an evidence-based protocol显示文摘 | Dewar C Selby C Jamieson K | 2008 | Emergency medicine Journal2008，25，7： | 1 |
| 17 | A predominantlyclonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality 显示文摘 | Loo VG Poirier L Miller MA Oughton M Libman MD Michaud S Bourgault AM Nguyen T Frenette C KellyM Vibien A Brassard P Fenn S? Dewar K Hudson TJ?Horn R Rene P Monczak Y Dascal A | 2005 | N Engl J Med2005，353，23： | 1 |
| 18 | Review semiconducting transparent thin films: their properties and applications 显示文摘 | Dewar Joshi J C | 1980 | 51 (12):6243 - 62511980，51，12： | 1 |
| 19 | Environmental Influences on Carbon Allocation in Pines 显示文摘 | Dewar R C Ludlow A R Doughterty P M | 1994 | Ecological Bulletins1994，43，： | 1 |
| 20 | Evaluating the communication process between interpreter and visitor显示文摘 | Ryan C Dewar K | 1995 | Tourism Management1995，16，4： | 1 |
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