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11篇 您的检索式:作者名="Dewi S"
    题名 作者 年代 出处 被引量
1Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma显示文摘The major type of human liver cancer is hepatocellular carcinoma(HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral(HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been difficult due to the heterogeneity and genetic complexity associated with this disease. A repertoire of animal models has been broadly used to study the pathophysiology and to develop potential treatment regimens for HBVassociated HCC. The use of these animal models has provided valuable genetic information and has been an important contributor to uncovering the factors involved in liver malignant transformation, invasion and metastasis. Recently, transposon-based mouse models are becoming more widely used in liver cancer research to interrogate the genome by forward genetics and also used to validate genes rapidly in a reverse genetic manner. Importantly, these transposon-based rapid reverse genetic mouse models could become crucial in testing potential therapeutic agents before proceeding to clinical trials in human. Therefore, this review will cover the use of transposon-based mouse models toaddress the problems of liver cancer, especially HBVassociated HCC occurrences in Asia.Amy P Chiu Barbara R Tschida Lilian H Lo Branden S Moriarity Dewi K Rowlands David A Largaespada Vincent W Keng 2015World Journal of Gastroenterology2015,21,42:2
2Stroke rehabilitation: analysis of repeated Barthel index measures 显示文摘Granger C V Dewis L S Peters N C 1979Arch Phys Med Rehabil1979,60,1:1
3The role of neutrophyl lymphocyte count ratio as an inflammatory marker in systemic lu-pus erythematosus 显示文摘Oehadima A Suryadinata H Dewi S 2013Acta Med Indones2013,45,3:1
4Protein kinase C beta selective inhihitor LY333531 ameliorates abnormal retinal haemodynamics in patients with diabetes 显示文摘Aiello LP Bursell S Dewies T 1999Diabetes1999,48,:1
5Optimising feedback using the Mini-CEX during the final semester programme显示文摘Dewi S Achmad TH 2010Meal Educ2010,44,1:1
6Empathy and conflict resolution in friendship relation among adolescents显示文摘Dewied M Branje S J T Meeus W H J 2007Aggressive rehavior2007,33,1:1
7Plant regeneration from anther cultures of several genotypes of indica rice tolerant to aluminum toxicity 显示文摘Dewi I S Purwoko B S Aswidinnoor H 2009Indones J Agrie Sci2009,2,:1
8A-gis Based Approach of Evacuation Model for Tsunami Risk Reduction 显示文摘Dewi R S 2012IDRiM Journal ($2185-8322)2012,2,2:1
9The role of neutrophyl lymphocyte count ratio as an in flammatory marker in systemic lupus erythematosus显示文摘Oehadian A Suryadinata H Dewi S 2013Acta Med Indones2013,45,:1
10The role of neutrophyl lymphocyte count ratio as an inflammatory marker in systemic lupus erythematosus显示文摘Oehadian A Suryadinata H Dewi S 2013Acta Med Indones2013,45,:1
11High occurrence of simultaneous mutation in target enzymes and MtrRCDE efflux system in quinolone - resistant Neisseria gonorrhoeae显示文摘Dewi BE Akira S Hayashi H 2004Sex T ransn Dis2004,31,:1
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