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| 1 | Bile leakage after loop closure vs clip closure of the cystic duct during laparoscopic cholecystectomy:A retrospective analysis of a prospective cohort显示文摘BACKGROUND Laparoscopic cholecystectomy(LC)is one of the most frequently performed surgical procedures.Cystic stump leakage is an underestimated,potentially life threatening complication that occurs in 1%-6%of the patients.With a secure cystic duct occlusion technique during LC,bile leakage becomes a preventable complication.AIM To investigate the effect of polydioxanone(PDS)loop closure of the cystic duct on bile leakage rate in LC patients.METHODS In this retrospective analysis of a prospective cohort,the effect of PDS loop closure of the cystic duct on bile leakage complication was compared to patients with conventional clip closure.Logistic regression analysis was used to develop a risk score to identify bile leakage risk.Leakage rate was assessed for categories of patients with increasing levels of bile leakage risk.RESULTS Of the 4359 patients who underwent LC,136(3%)underwent cystic duct closure by a PDS loop.Preoperatively,loop closure patients had significantly more complicated biliary disease compared to the clipped closure patients.In the loop closure cohort,zero(0%)bile leakage occurred compared to 59 of 4223(1.4%)clip closure patients.For patients at increased bile leakage risk(risk score≥1)rates were 1.6%and up to 13%(4/30)for clip closure patients with a risk score≥4.This risk increase paralleled a stepwise increase of actual bile leakage complication for clip closure patients,which was not observed for loop closure patients.CONCLUSION Cystic duct closure with a PDS loop during LC may reduce bile leakage in patients at increased risk for bile leakage. | Sandra C Donkervoort Lea M Dijksman Aafke H van Dijk Emile A Clous Marja A Boermeester Bert van Ramshorst Djamila Boerma | 2020 | World Journal of Gastrointestinal Surgery2020，12，1： | 4 |
| 2 | Systematic review of cystic duct closure techniques in relation to prevention of bile duct leakage after laparoscopic cholecystectomy显示文摘AIM To study the effect of different techniques of cystic duct closure on bile leakage after laparoscopic cholecystectomy(LC) for biliary disease.METHODS A systematic search of MEDLINE, Cochrane and EMBASE was performed. Rate of cystic duct leakage(CDL) was the primary outcome. Risk of bias was evaluated. Odds ratios were analyzed for comparison of techniques and pooled event rates for non-comparative analyses. Pooled event rates were compared for each of included techniques.RESULTS Out of 1491 articles, 38 studies were included. A total of 47491 patients were included, of which 38683(81.5%)underwent cystic duct closure with non-locking(metal)clips. All studies were of low-moderate methodological quality. Only two studies reported separate data on uncomplicated and complicated gallbladder disease. For overall CDL, an odds ratio of 0.4(95%CI: 0.06-2.48)was found for harmonic energy vs clip closure and an odds ratio of 0.17(95%CI: 0.03-0.93) for locking vs non-locking clips. Pooled CDL rate was around 1% for harmonic energy and metal clips, and 0% for locking clips and ligatures. CONCLUSION Based on available evidence it is not possible to either recommend or discourage any of the techniques for cystic duct closure during LC with respects to CDL,although data point out a slight preference for locking clips and ligatures vs other techniques. No separate recommendation can be made for complicated gallbladder disease. | Aafke H van Dijk Stijn van Roessel Philip R de Reuver Djamila Boerma Marja A Boermeester Sandra C Donkervoort | 2018 | World Journal of Gastrointestinal Surgery2018，10，6： | 3 |
| 3 | The dissolution of Na2O-MgO-CaO-SiO2 glass in aqueous HF solutions 显示文摘 | SPIERINGS G A C M van DIJK J | 1987 | J Mater Sci1987，22，： | 2 |
| 4 | Multi-phase flow modeling of air sparging显示文摘 | Van Dijke M Van der Zee I J Van Duijn C J | 1995 | Advances in Water Resources1995，18，6： | 1 |
| 5 | Effects of atorvastatin on fasting and postprandial complement component 3 response in familial combined hyperlipidemia显示文摘 | VERSEYDEN C MEIJSSEN S van DIJK H | 2003 | J Lipid Res2003，44，11： | 1 |
| 6 | Sketch input for conceptual surface design显示文摘 | Van Dijk C G C Mayer A A C | 1997 | Computer in Industry1997，34，12： | 1 |
| 7 | Anaerobic oxidization ofmethane in a minerotrophic peatland : enrichment of nitrite-dependent methane-oxidizing bacteria 显示文摘 | ZHU Baoli VAN DIJK G FRITZ C | 2012 | Applied andEnvironmental Microbiology2012，78，24： | 1 |
| 8 | Not self-focused attention but negative beliefs affect poor social performance in social anxiety:An investigation of pathways in the social anxiety-social rejection relationship显示文摘 | Voncken M J Dijk C de Jong P J | 2010 | Behaviour Research and Therapy2010，48，10： | 1 |
| 9 | Pulmonary complications after T-cell-depleted allogeneic stem cell transplantation:low incidence and strong association with acute graft-versus-host disease显示文摘 | Huisman C van der Straaten HM Canninga-van Dijk MR | 2006 | Bone Marrow Transplant2006，38，8： | 1 |
| 10 | Cloning and expression of a functional estrogen recep- tor-α from African catfish (Clarias gariepinus) pitui- tary 显示文摘 | Teves A C C Granneman J C M Van Dijk W | 2003 | J Mol Endocrinol2003，30，： | 1 |
| 11 | Avian defensin 显示文摘 | Van Dijk A Veldhuizen E J Kalkhove S I C | 2008 | Veteri Immunolo Immunopatholo2008，124，： | 1 |
| 12 | TGF-beta signalling from cell membrane to nucleus through SMAD proteins显示文摘 | Heldin C H Miyazono K ten Dijke P | 1997 | Nature1997，390，6659： | 1 |
| 13 | The influence of horizontal internal baffles on the flow pattern in dense fluidized beds by X-ray investigation 显示文摘 | van Dijk J J Hoffmann A C Cheesman D | 1998 | Powder Technology1998，98，3： | 1 |
| 14 | New insights in computer - aided conceptual design显示文摘 | Cpsper G C van Dijk | 1995 | Design Studies1995，16，1： | 1 |
| 15 | Arthroscopy for problems after ankle fracture显示文摘 | Van Dijk C N Verhagen R A Tol J L | 1997 | J Bone Joint Surg Br1997，79，2： | 1 |
| 16 | Stable transfection of malaria parasite blood stages显示文摘 | VAN DIJK M R WATERS A P JANSE C J | 1995 | Science1995，268，5215： | 1 |
| 17 | Pathogenesis of diabetic nephropathy显示文摘 | van Dijk C Berl T | 2004 | Rev Endocr Metab Disord2004，5，3： | 1 |
| 18 | TGF-β1 signaling from cell membrane to nucleus through SMAD protein显示文摘 | Heldin C H Miyazono K ten Dijke P | 1997 | Nature1997，390，6659： | 1 |
| 19 | Circa- dian expression of clock genes and clock-controlled genes in the rat retina显示文摘 | KAMPHUIS W CAILOTTO C DIJK F | 2005 | Biochem Bioph Res Co2005，330，： | 1 |
| 20 | New insights into TGF-beta/ Smad signaling显示文摘 | Ten Dijke P I-I511 C S | | 0，，05： | 1 |
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