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| 1 | Performance of the Montreal classification for inflammatory bowel diseases显示文摘AIM:To validate the Montreal classification system for Crohn's disease(CD) and ulcerative colitis(UC) within the Netherlands.METHODS:A selection of 20 de-identified medical records with an appropriate representation of the inflammatory bowel disease(IBD) sub phenotypes were scored by 30 observers with different professions(gastroenterologist specialist in IBD,gastroenterologist in training and IBD-nurses) and experience level with IBD patient care.Patients were classified according to the Montreal classification.In addition,participants were asked to score extra-intestinal manifestations(EIM) and disease severity in CD based on their clinical judgment.The inter-observer agreement was calculated by percentages of correct answers(answers identical to the 'expert evaluation') and Fleiss-kappa(k).Kappa cutoffs:< 0.4-poor; 0.41-0.6-moderate; 0.61-0.8-good; > 0.8 excellent.RESULTS:The inter-observer agreement was excellent for diagnosis(k = 0.96),perianal disease(k = 0.92) and disease location in CD(k = 0.82) and good for age of onset(k = 0.67),upper gastrointestinal disease(k = 0.62),disease behaviour in CD(k = 0.79) and disease extent in UC(k = 0.65).Disease severity in UC was scored poor(k = 0.23).The additional items resulted in a good inter-observer agreement for EIM(k = 0.68) and a moderate agreement for disease severity in CD(k = 0.44).Percentages of correct answers over all Montreal items give a good reflection of the inter-observer agreement(> 80%),except for disease severity(48%-74%).IBD-nurses were significantly worse in scoring upper gastrointestinal disease in CD compared to gastroenterologists(P = 0.008) and gastroenterologists in training(P = 0.040).Observers with less than 10 years of experience were significantly better at scoring UC severity than observers with 10-20 years(P = 0.003) and more than 20 years(P = 0.003) of experience with IBD patient care.Observers with 10-20 years of experience with IBD patient care were significantly better at scoring upper gastrointestinal disease in CD than observers with less than 10 years(P = 0.007) and more than 20 years(P = 0.007) of experience with IBD patient care.CONCLUSION:We found a good to excellent interobserver agreement for all Montreal items except for disease severity in UC(poor). | Lieke M Spekhorst Marijn C Visschedijk Rudi Alberts Eleonora A Festen Egbert-Jan van der Wouden Gerard Dijkstra Rinse K Weersma | 2014 | World Journal of Gastroenterology2014，20，41： | 4 |
| 2 | 13C andl5N natural abundance of the soil microbial biomass显示文摘 | Dijkstra P Ishizu A Doucett R Hart S C Schwartz E Menyailo O V Hungate B A | 2006 | Soil Biology & Biochemistry2006，38，： | 1 |
| 3 | Simulation of nutrient digestion,absorption and outflow in the rumen:model description显示文摘 | DIJKSTRA J NEALH D S C BEEVER D E | 1992 | The Journal of Nutrition1992，122，11： | 1 |
| 4 | The role of arginine 47 in the cyclization and coupling reactions of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 implications for product inhibition and product specificity显示文摘 | VEEN BA V UITDEHAAG J C DIJKSTRA B W | 2000 | Eur J Biochem2000，267，： | 1 |
| 5 | Maternal antibody transmission and breeding in the Black-headed Gull Laras ridibundus显示文摘 | Mlleer W Groothuis T G G Dijkstra C | 2004 | Funcrional Ecology2004，18，： | 1 |
| 6 | The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3 显示文摘 | Dijkstra C D Dtipp E A Joling P | 1985 | Immunology1985，54，： | 1 |
| 7 | Thermosensitive micelle-forming block copolymers of poly ( ethylene glycol ) and poly ( N-isopropylacrylamide) 显示文摘 | Topp M D C Dijkstra P J | 1997 | Macromolecules1997，30，： | 1 |
| 8 | Multiple sclerosis and vitamin D:an update显示文摘 | VanAmerongen B M Dijkstra C D Lips P | 2004 | Eur J Clin Nutr2004，58，8： | 1 |
| 9 | The heterogeneity of mononuclear phagocytes in lymphoid organs:distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1,ED2 and ED3显示文摘 | DIJKSTRA C D D?PP E A JOLING P | 1985 | Immunology1985，54，3： | 1 |
| 10 | Sex identification in birds using two CHD genes显示文摘 | Griffiths R Daan S Dijkstra C | 1996 | Proc R Soc Lond B Biol Sci1996，263，1374： | 1 |
| 11 | Brood size manipulations in the kestrel ( Falcotinnunadus ) : Effects on offspring and parent survival 显示文摘 | Dijkstra C Bult A Bijlsma S Daan S Meijer T | 1990 | J Anim Ecol1990，59，： | 1 |
| 12 | Hydroconsolidation and subsidence of loess: studies from China, Russia, North America and Europe显示文摘 | ROGERS C D E DIJKSTRA T A SMALLEY I J | 1994 | Engineering Geology1994，37，2： | 1 |
| 13 | Raman spectroscopy as a detection method for liquid-separation tech- niques显示文摘 | DIJKSTRA R J ARIESE F GOOIJER C | 2005 | Tr Anal Chem2005，24，： | 1 |
| 14 | Family planning in the Kestrel (Falco tinnunculus):the ultimate control of covariance of laying date and clutch size 显示文摘 | DAAN S DIJKSTRA C TINBERGEN J M | 1990 | Behaviour1990，114，14： | 1 |
| 15 | Leaching of heavy metals from contaminated soils: an experimental and modeling study 显示文摘 | Dijkstra J J Meeussen J C L Comans R N J | 2004 | Environ Sci Technol2004，38，： | 1 |
| 16 | The usefulness of the gfp reporter gene for monitoring Agrobacterium-mediated transformation of potato dihaploid and tetraploid genotypes显示文摘 | Rakosy-Tiean E Aurori C M Dijkstra C et 01 | 2007 | Plant Cell Rep2007，26，5： | 1 |
| 17 | The loess of north- central China: geotechnical properties and their relation to slope sta- bility显示文摘 | Dijkstra T A Rogers C D F Smalley I J | 1994 | Engineering Geology1994，36，： | 1 |
| 18 | Leaching of heavy metals from contaminated soils:an experimental and modeling study显示文摘 | Dijkstra J J Meeussen J C L Comans R N J | 2004 | Environ Sci Technol2004，38，： | 1 |
| 19 | Sex identi- fication in birds using two CHD genes显示文摘 | GRIFFITHS R DAAN S DIJKSTRA C | 1996 | Proc Biol Sci1996，263，1374： | 1 |
| 20 | Efficient immunocastration of male piglets by immunoneutralization of GnRH using a new GnRH-like peptide显示文摘 | Meloen R H Turkstra J A Lankhof H Puijk W C Schaaper W M Dijkstra G Wensing C J Oonk R B | 1994 | Vaccine1994，12，8： | 1 |
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