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您的检索式：作者名="Dingchang ZHENG"
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| 1 | Index of microcirculatory resistance: state-of-the-art and potential applications in computational simulation of coronary artery disease显示文摘The dysfunction of coronary microcirculation is an important cause of coronary artery disease(CAD).The index of microcirculatory resistance(IMR)is a quantitative evaluation of coronary microcirculatory function,which provides a significant reference for the prediction,diagnosis,treatment,and prognosis of CAD.IMR also plays a key role in investigating the interaction between epicardial and microcirculatory dysfunctions,and is closely associated with coronary hemodynamic parameters such as flow rate,distal coronary pressure,and aortic pressure,which have been widely applied in computational studies of CAD.However,there is currently a lack of consensus across studies on the normal and pathological ranges of IMR.The relationships between IMR and coronary hemodynamic parameters have not been accurately quantified,which limits the application of IMR in computational CAD studies.In this paper,we discuss the research gaps between IMR and its potential applications in the computational simulation of CAD.Computational simulation based on the combination of IMR and other hemodynamic parameters is a promising technology to improve the diagnosis and guide clinical trials of CAD. | Yingyi GENG Xintong WU Haipeng LIU Dingchang ZHENG Ling XIA | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，2： | 1 |
| 2 | Estimation of mean arterial pressure from the oscillometric cuff pressure: comparison of different techniques显示文摘 | Zheng Dingchang Amoore JN | 2011 | Medical and Biological Engineering and Computing2011，49，： | 1 |
| 3 | A preliminary observation on rod cell photobiomodulation in treating diabetic macular edema显示文摘Purpose:To evaluate the safety and effectiveness of photobiomodulation(PBM)in the treatment of diabetic macular edema(DME).Methods:It was a single-center,self-controlled prospective study.The clinical records of 12 diabetic retinopathy patients(5 males and 7 females,20 eyes in total)who were treated with PBM for DME at the Second Affiliated Hospital,Zhejiang University School of Medicine,were analyzed.The mean age was 56(26–68)years.All the participants received PBM treatment during darkness at night in no less than 5 days per week and no less than 8 h per day.In the baseline check and follow-up checks(1,2,6,10,and 12 months after the start of treatment),the best-corrected visual acuity,the thickness of the retina in the macula,and the changes of the fundus lesions were observed.Wilcoxon signed rank test was used to compare the results before and after treatment.P<0.05 was considered statistically significant.Results:No fundus complication was observed during follow-up checks.In baseline and 12-month follow-up checks,the best-corrected visual acuity was 71.7512.47 and 79.5010.85,maximal retinal thickness in macular area was 390.9577.12μm and 354.1355.03μm,average retinal thickness in macular area was 334.2536.45μm and 314.3133.28μm,foveal thickness was 287.0046.79μm and 265.6367.14μm.The best-corrected visual acuity,average retinal thickness in macular area in consecutive follow-up results except that in the 1st month showed significant difference compared with baseline results.There were significant difference between every follow-up result and baseline result of maximal retinal thickness in macular area(P<0.05).All follow-up results of foveal thickness were not significantly different(P>0.05)from the baseline result,except that in the 6th month(P?0.049).Obvious improvement could be observed in retinal fundus fluorescein angiography images.Conclusions:PBM is a safe and effective treatment of DME,which deserves further investigation. | Zhiqing Chen Binbin Chen Peike Hu Haipeng Liu Dingchang Zheng | 2022 | Advances in Ophthalmology Practice and Research2022，2，2： | 0 |
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