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| 1 | Two immunomod- ulators, curcumin and sulfasalazine,enhance IDV antiretroviral activity in HIV-1 persistently infected cells 显示文摘 | Riva DA Femdndez-Larrosa PN Dolcini GL | 2008 | Archives of Virology2008，153，3： | 1 |
| 2 | C0,α regularity of ω-minima显示文摘 | Dolcini A Esposito L Fusco N | 1996 | Boll Unione Mat Ital Ser A1996，10，7： | 1 |
| 3 | Lurch Avoidance Strategy and Its Implementation in AMT Vehicles 显示文摘 | DOLCINI P CARLOS C BECHART H | 2008 | Mechatronics2008，18，5： | 1 |
| 4 | Observer-based Optimal Control of Dry Clutch Engagement显示文摘 | DOLCINI P BECHART H | 2007 | Oil & Gas Science and Technology2007，62，4： | 1 |
| 5 | Addition of heparin binding sites strongly increases the bone forming capabilities of BMP9 in vivo显示文摘Bone Morphogenetic proteins(BMPs)like BMP2 and BMP7 have shown great potential in the treatment of severe bone defects.In recent in vitro studies,BMP9 revealed the highest osteogenic potential compared to other BMPs,possibly due to its unique signaling pathways that differs from other osteogenic BMPs.However,in vivo the bone forming capacity of BMP9-adsorbed scaffolds is not superior to BMP2 or BMP7.In silico analysis of the BMP9 protein sequence revealed that BMP9,in contrast to other osteogenic BMPs such as BMP2,completely lacks so-called heparin binding motifs that enable extracellular matrix(ECM)interactions which in general might be essential for the BMPs’osteogenic function.Therefore,we genetically engineered a new BMP9 variant by adding BMP2-derived heparin binding motifs to the N-terminal segment of BMP9′s mature part.The resulting protein(BMP9 HB)showed higher heparin binding affinity than BMP2,similar osteogenic activity in vitro and comparable binding affinities to BMPR-II and ALK1 compared to BMP9.However,remarkable differences were observed when BMP9 HB was adsorbed to collagen scaffolds and implanted subcutaneously in the dorsum of rats,showing a consistent and significant increase in bone volume and density compared to BMP2 and BMP9.Even at 10-fold lower BMP9 HB doses bone tissue formation was observed.This innovative approach of significantly enhancing the osteogenic properties of BMP9 simply by addition of ECM binding motifs,could constitute a valuable replacement to the commonly used BMPs.The possibility to use lower protein doses demonstrates BMP9 HB’s high translational potential. | Claudia Siverino Shorouk Fahmy-Garcia Viktoria Niklaus Nicole Kops Laura Dolcini Massimiliano Maraglino Misciagna Yanto Ridwan Eric Farrell Gerjo JVMvan Osch Joachim Nickel | 2023 | Bioactive Materials2023，，11： | 1 |
| 6 | Cell-Free HIV Type 1 Infection is Restricted in the Human Trophoblast Choriocarcinoma BeWo Cell Line, Even With Expression of CD4, CXCR4 and CCR5 显示文摘 | G Dolcini M Derrien G Chaouat | 2003 | AIDS Research and Human Retroviruses2003，19，10： | 1 |
| 7 | Multiband photometry of the blazar PKS 0537-441:a major active state in December 2004-March 2005显示文摘 | DOLCINI A COVINO S TREVES A | 2005 | Astronomy&Astrophysics2005，443，3： | 1 |
| 8 | Role of scaffold internal structure on in vivo bone formation in macroporous calcium phosphate bioceramics显示文摘 | Maddalena Mastrogiacomo Silvia Scaglione Roberta Martinetti Laura Dolcini Francesco Beltrame Ranieri Cancedda Rodolfo Quarto | 2006 | Biomaterials2006，，17： | 1 |
| 9 | A new window into adolescents' worlds:The impact of online social interaction on risk behavior显示文摘 | DOLCINI MM | 2014 | J Adoles Health2014，54，5： | 1 |
| 10 | Physical and Chemical Aspects of a New Porous Hydroxyaptite显示文摘 | Martinetti R Dolcini L | 2005 | Anal Bioanal Chem2005，381，3： | 1 |
| 11 | Two immunomodulators, curcumin and sulfasalazine, enhance IDV antiretroviral activity in HIV-1 persistent- ly infected cells显示文摘 | D A Riva P N Ferna ndez-Larrosa G L Dolcini | 2008 | Arch Virol2008，153，： | 1 |
| 12 | Two immunomodulators, curcumin and sulfasalazine, enhance IDV antiretroviral activity in HIV - 1 persistently infected cells显示文摘 | Riva DA Fernandez - Larrosa PN Dolcini GL | 2008 | Arch Virol2008，153，3： | 1 |
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