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| 1 | Diabetic foot disease:From the evaluation of the “foot at risk” to the novel diabetic ulcer treatment modalities显示文摘The burden of diabetic foot disease(DFD) is expected to increase in the future. The incidence of DFD is still rising due to the high prevalence of DFD predisposing factors. DFD is multifactorial in nature; however most of the diabetic foot amputations are preceded by foot ulceration. Diabetic peripheral neuropathy(DPN) is a major risk factor for foot ulceration. DPN leads to loss of protective sensation resulting in continuous unconscious traumas. Patient education and detection of high risk foot are essential for the prevention of foot ulceration and amputation. Proper assessment of the diabetic foot ulceration and appropriate management ensure better prognosis. Management is based on revascularization procedures, wound debridement, treatment of infection and ulcer offloading. Management and type of dressing applied are tailored according to the type of wound and the foot condition. The scope of this review paper is to describe the diabetic foot syndrome starting from the evaluation of the foot at risk for ulceration, up to the new treatment modalities. | Noha Amin John Doupis | 2016 | World Journal of Diabetes2016，7，7： | 39 |
| 2 | Gestational diabetes from A to Z显示文摘Gestational diabetes mellitus(GDM) is defined as any degree of hyperglycaemia that is recognized for the first time during pregnancy. This definition includes cases of undiagnosed type 2 diabetes mellitus(T2 DM) identified early in pregnancy and true GDM which develops later. GDM constitutes a greater impact on diabetes epidemic as it carries a major risk of developing T2 DM to the mother and foetus later in life. In addition, GDM has also been linked with cardiometabolic risk factors such as lipid abnormalities, hypertensive disorders and hyperinsulinemia. These might result in later development of cardiovascular disease and metabolic syndrome. The understanding of the different risk factors, the pathophysiological mechanisms and the genetic factors of GDM, will help us to identify the women at risk, to develop effective preventive measures and to provide adequate management of the disease. Clinical trials have shown that T2 DM can be prevented in women with prior GDM, by intensive lifestyle modification and by using pioglitazone and metformin. However, a matter of controversy surrounding both screening and management of GDM continues to emerge, despite several recent welldesigned clinical trials tackling these issues. The aim of this manuscript is to critically review GDM in a detailed and comprehensive manner, in order to provide a scientific analysis and updated write-up of different related aspects. | AbdelHameed Mirghani Dirar John Doupis | 2017 | World Journal of Diabetes2017，8，12： | 10 |
| 3 | 欧洲医疗卫生信息化:向更高的目标发展显示文摘医疗卫生信息化在欧洲信息化2002和2005行动计划里,已经成为欧盟委员会战略优先项目。作者比较了欧盟15个国家医疗卫生信息化的现状和2004年5月后欧盟 25个国家的最新发展趋势和优先权,分析了医疗卫生信息化的动力和障碍。欧洲医疗卫生信息化到底取得多少进展?什么是未来的战略目标?哪些障碍等待克服?如何跨越这些障碍? | Persephone Doupi Pivi Hmlinen Pekka Ruotsalainen 沈健(编译) | 2006 | 中国卫生产业2006，，1： | 7 |
| 4 | Total serum bilirubin does not affect vascular reactivity in patients with diabetes显示文摘 | Yeh Y Doupis J Rahangdale S | 2009 | Vasc Med2009，14，2： | 1 |
| 5 | Microvascular reactivity and inflammatory cytokines in painful and painless peripheral diabetic neuropathy显示文摘 | Doupis J Lyons T E Wu S | 2009 | J Clin Endocrinol Metab2009，94，： | 1 |
| 6 | Acute hyperhomocys- teinemia impairs endothelium function in subjects with type 2 diabe- tes mellitus显示文摘 | Doupis J EleftheriadouI Kokkinos A | 2010 | Exp Clin Endocrinol Diabetes2010，118，7： | 1 |
| 7 | Acute hyperhomocysteinemia impairs endothelium function in subjects with type 2 diabetes mellitus显示文摘 | Doupis J Eleftheriadou I Kokkinos A | | 0，，07： | 1 |
| 8 | Management of diabetic foot ulcers 显示文摘 | Alexiadou K Doupis J | 2012 | Dia- betes Thor2012，3，1： | 1 |
| 9 | Supra and infra levator neurovascular pathways to the penile corpora cavemosa显示文摘 | BENOIT G DOUPY S QUILLARD J | 1999 | J Anat1999，195，5： | 1 |
| 10 | Microvaseular reacti vity and inflammatory cytokines in painful and painless peri- pheral diabetic neuropathy显示文摘 | DOUPIS J LYONS T E WU S | 2009 | Journal of Clinical Endocrinolo- gy Metabolism2009，94，6： | 1 |
| 11 | Microvascular reactivity and inflammatory cytokines in painful and painless peripheral diabetic neuropathy显示文摘 | Doupis J Lyons T E Wu S | 2009 | J Clin Endocrinol Metab2009，94，6： | 1 |
| 12 | Linagliptin/Metformin fixed-dose com- bination treatment : a dual attack to type 2 diabetes pathophysiolo- gy显示文摘 | KOLIAKI C DOUPIS J | 2012 | Adv Ther2012，29，12： | 1 |
| 13 | Incretin-hased therapy: a powerful and promising weapon in the treatment of type 2 diabetes mellitus 显示文摘 | Koliaki C Doupis J | 2011 | Diabetes Ther2011，2，2： | 1 |
| 14 | Microvascular reactivity and inflamma- tory cytokines in painful and painless peripheral diabetic neuropathy 显示文摘 | Doupis J Lyons TE Wu S | 2009 | J Clin Endocrinol Metab2009，94，6： | 1 |
| 15 | DPP4 inhibitors:from sitagliptin monotherapy to the new alogliptin-pioglitazone combination therapy显示文摘 | Argyrakopoulou G Doupis J | | 0，，03： | 1 |
| 16 | Microvascular reactivity and inflammatory cytokines in painful and painless peripheral diabetic neuropathy显示文摘 | Doupis J Lyons T E Wu S | 2009 | J Clin Endoerinol Metab2009，94，6： | 1 |
| 17 | Management of Diabetic Foot Ulcers 显示文摘 | Alexiadou K Doupis J | 2012 | Diabetes Ther2012，3，1： | 1 |
| 18 | Microvascular reactivity and inflammatory cytokines in painful and painless peripheral diabetic neu- ropathy 显示文摘 | Doupis J Lyons TE Wu S | 2009 | Jclin Endocrinol Melab2009，94，6： | 1 |
| 19 | Microvascular reactivity and inflammatory cytokines in painful and painless peripheral diabetic neuropathy显示文摘 | Doupis J Lyons TE Wu S | 2009 | J Clin Endocrinol Metab2009，94，6： | 1 |
| 20 | Microvascular reactivity and inflammatory cytokines in painful and painless peripheral diabetic neuropathy显示文摘 | Doupis J Lyons TE Wu S | 2009 | J Clin Endocrinol Metab2009，94，6： | 1 |
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