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161篇 您的检索式:作者名="Drew D M"
    题名 作者 年代 出处 被引量
1Brain changes in diabetes mellitus patients withgastrointestinal symptoms显示文摘Diabetes mellitus is a common disease and its prevalence is increasing worldwide. In various studies up to 30%-70% of patients present dysfunction and complications related to the gut. To date several clinical studies have demonstrated that autonomic nervous system neuropathy and generalized neuropathy of the central nervous system(CNS) may play a major role. This systematic review provides an overview of the neurodegenerative changes that occur as a consequence of diabetes with a focus on the CNS changes and gastrointestinal(GI) dysfunction. Animal models where diabetes was induced experimentally support that the disease induces changes in CNS. Recent investigations with electroencephalography and functional brain imaging in patients with diabetes confirm these structural and functional brain changes. Encephalographic studies demonstrated that altered insular processing of sensory stimuli seems to be a key player in symptom generation. In fact one study indicated that the more GI symptoms the patients experienced, the deeper the insular electrical source was located. The electroencephalography was often used in combination with quantitative sensory testingmainly showing hyposensitivity to stimulation of GI organs. Imaging studies on patients with diabetes and GI symptoms mainly showed microstructural changes,especially in brain areas involved in visceral sensory processing. As the electrophysiological and imaging changes were associated with GI and autonomic symptoms they may represent a future therapeutic target for treating diabetics either pharmacologically or with neuromodulation.Anne M Drewes Eirik Søfteland Georg Dimcevski Adam D Farmer Christina Brock Jens B Frøkjær Klaus Krogh Asbjørn M Drewes 2016World Journal of Diabetes2016,7,2:4
2The interaction of reaction-bonded silicon carbide and Inconel 600 with a nickel-based brazing alloy显示文摘Mcdermid J R Pugh M D Drew R A L 1989Metallurgical Transactions A1989,20,:1
3FA polydisperse model for bubbly two-phase flow around a surface ship显示文摘Carrica P M Drew D Bonetto F 1999International Journal of Multiphase Flow1999,25,:1
4Multiple paternity in a natural population of a wild tobacco fly, Bactrocera cacuminata (Diptera: Tephritidae), assessed by microsatellite DNA markers 显示文摘Song S D Drew R A Hughes J M 2007Molecular Ecology2007,16,11:1
5Entropy minimization for shadow removal 显示文摘FINLAYSON G D DREW M S LU C 2009International Journal of Computer Vision2009,85,1:1
6Savoy: Absorption of methionine and 2-hydroxy-4-methylthiobutoanic acid in conventional and germ-free chickens显示文摘Drew M D Van Kessel A G Maer z D D 2003Poultry Science2003,82,7:1
7Carbon diox- ide capture using ionic liquid 1-butyl-3-methylimidazolium acetate 显示文摘Shiflett M B Drew D W Cantini R A 2010Energy & Fuels2010,24,10:1
8Deriving spectra from colors and rendering light interference 显示文摘Sun Y Fracehia F D Calvert T W Drew M S 1999IEEE Computer Graphics and Applications1999,19,4:1
9The in- teraction of background ocean air bubbles with a sur- face ship显示文摘Carrica P M Bonetto F J Drew D A etal 1998Int J Numer Methods Fluids1998,28,:1
10Regeneration of rapid escape reflex pathways in earthworms 显示文摘DREWES C D VINING E P ZORAN M J 1988Amer Zool1988,28,:1
11A polydis- perse model for bubbly two phase flow around a sur- face ship显示文摘Carrica P M Drew D Bonetto F 1999Int J Multiphase Flow1999,25,2:1
12A sub grid air entrainment model for breaking bow waves and naval surface ships 显示文摘Moraga F J Carrica P M Drew D A 2008Computers and Fluids2008,37,:1
13Entropy minimization for shadow removal 显示文摘Pinlayson G D Drew M S Lu C 2009International Journal of Computer Vision2009,85,1:1
14A polydisperse model for bubbly two-phrase flow around a surface ship 显示文摘CARRICA P M DREW D A BONETTO F J 1999Int J Multiphase Flow1999,25,:1
15Color constancy: general- ized diagonal transforms suffice 显示文摘Finlayson G D Drew M S Funt B V 1994Journal of the Optical Socie- ty of America1994,11,11:1
16Pharmacokinetics of ceftiofur in llamas and alpacas 显示文摘Drew M L Johnson L Pugh D 2004Vet Pharmacol Ther2004,27,:1
17Polydisperse model for bubbly two phases flow around a surface ship显示文摘Carrica P M Drew D Bonettor F 0,,2:1
18Escape reflex development during posterior regeneration in the earthworm显示文摘Welch M F Drewes C D 1985Eisenia foetida J EXP ZOOL1985,235,1:1
19Multiple paternity in a natural population of a wild tobacco fly, Bactrocera cacuminata ( Diptera: Tephritidae), assessed by microsatellite DNA markers 显示文摘Song S D Drew R A I Hughes J M 2007Molecular Ecology2007,16,11:1
20Open-cell reaction bon- ded silicon nitride foams: Fabrication and characterization 显示文摘Alem A Pugh M D Drew R A L 2014J Eur Ceram Soe2014,34,:1
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