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| 1 | 循证指南更新:成人发作性偏头痛预防的药物治疗显示文摘目的提供偏头痛预防治疗的指南更新推荐,所提出的临床问题是什么样的药物治疗可有效预防偏头痛发作?方法作者对1999年6月—2009年5月间发表的研究使用结构式的评价程序来分类不同(美国可获得)药物对偏头痛预防的效果。结果和推荐作者评价了284篇摘要,最后对29篇包含Ⅰ类或Ⅱ类证据的文章进行综述。双丙戊酸、丙戊酸钠、托吡酯、美托洛尔、普萘洛尔和噻吗洛尔能有效预防偏头痛,应该用于偏头痛患者以减少发作频率及程度(A级证据)。夫罗曲坦可有效预防月经性偏头痛(A级证据)。拉莫三嗪对偏头痛预防无效(A级证据)。 | 邹静 李颖 冯智英 李焰生 Silberstein SD Holland S Freitag F Dodick DW Argoff C Ashman E | 2012 | 神经病学与神经康复学杂志2012，9，2： | 38 |
| 2 | 循证指南更新:非甾体类抗炎药和其他辅助治疗预防成人发作性偏头痛显示文摘目的为偏头痛预防性治疗提供最新循证推荐。所提出的临床问题是非甾体类抗炎药(NSAIDs)或其他辅助治疗是否对偏头痛预防有效?方法作者对1999年6月—2009年5月间发表的研究使用结构式的评价程序来分类不同药物对偏头痛预防的效果。结果作者总共回顾了284篇摘要,包括49篇偏头痛预防治疗的Ⅰ级或Ⅱ级证据,其中15篇为涉及非传统治疗、NSAIDs及其他辅助治疗的研究,予以了评价。推荐蜂斗菜对偏头痛预防治疗有效,应被用于偏头痛患者以降低偏头痛发作频率及严重程度(A级推荐)。非诺洛芬、布洛芬、酮洛芬、萘普生、萘普生钠、雏菊、镁剂、核黄素及组胺皮下注射对偏头痛预防很可能有效(B级推荐)。认为可能有效的药物包括赛庚啶、辅酶Q10、雌激素、甲芬那酸及氟比洛芬(C级推荐)。矛盾不一致或不足以支持或反对使用的药物包括阿司匹林、吲哚美辛、ω-3及高压氧。孟鲁司特对偏头痛预防治疗很可能无效(B级证据)。 | 华驾略 蒋仙国 季伟华 李焰生 Holland S Silberstein SD Freitag F Dodick DW Argoff C Ashman E | 2012 | 神经病学与神经康复学杂志2012，9，2： | 17 |
| 3 | Pulmonary infection control window in treatment of severe respiratory failure of chronic obstructive pulmonary diseases: a prospective, randomized controlled, multi-centred study显示文摘Background Early withdraw from invasive mechanical ventilation (MV) followed by noninvasive MV is a new strategy for changing modes of treatment. This study was conducted to estimate the feasibility and the efficacy of early extubation and sequential noninvasive MV commenced at beginning of pulmonary infection control window in patients with exacerbated hypercapnic respiratory failure caused by chronic obstructive pulmonary diseases (COPD). Methods A prospective, randomized controlled study was conducted in eleven teaching hospitals' respiratory or medical intensive care units in China. Ninety intubated COPD patients with severe hypercapnic respiratory failure triggered by pulmonary infection (pneumonia or purulent bronchitis) were involved in the study. When the pulmonary infection had been controlled by antibiotics and comprehensive therapy, the 'pulmonary infection control window (PIC window)' has been reached. Each case was randomly assigned to study group (extubation and noninvasive MV via facial mask immediately) or control group (invasive MV was received continuously after PIC window by using conventional weaning technique).Results Study group (n=47) and control group (n=43) had similar clinical characteristics initially and at the time of PIC window. Compared with control group, study group had shorter duration of invasive MV [(6.4±4.4) days vs (11.3±6.2) days, P=0.000], lower rate of ventilator associated pneumonia (VAP) (3/47 vs 12/43, P=0.014), fewer days in ICU [(12±8) days vs (16±11) days, P=0.047] and lower hospital mortality (1/47 vs 7/43, P=0.025).Conclusions In COPD patients requiring intubation and invasive MV for hypercapnic respiratory failure, which is exacerbated by pulmonary infection, early extubation followed by noninvasive MV initiated at the start of PIC window may decrease significantly the duration of invasive MV, the risk of VAP and hospital mortality. | Wang, C Zhan, QY Cao, ZX Wei, LQ Cheng, ZZ Liu, S Zhang, JL Chen, RC Luo, Q Niu, SF Zhu, L Wu, DW Fang, BM Wu, TH Wang, CZ Liu, YN | 2005 | Chinese Medical Journal2005，，19： | 6 |
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| 8 | Sleep-disordered breathjing and periodic limb movements in sleep in older patients with schizophrenia显示文摘 | Ancoli-Israel S Martin J Jones DW | 1999 | Biol Psychiatry1999，45，11： | 1 |
| 9 | Development of adverse sequelae in children born with subclinicalcongenital Toxoplasma infection显示文摘 | Wilson CB Remington JS Stagno S Reynolds DW | 1980 | Pediatrics1980，66，： | 1 |
| 10 | Effect of retinol palmitate on ovulation rate and embryo quality in superovulated cattle显示文摘 | Shaw DW Farin P W Washburn S P | 1995 | Theriogenology1995，44，： | 1 |
| 11 | Hyaluronan facilitates trans- forming growth factor- beta( 1 ) - mediated fibroblast proliferation显示文摘 | Meran S Thomas DW Stephens P | 2008 | Journal of Biological Chemistry2008，283，： | 1 |
| 12 | Incidence and preventability of adverse drug events in hospitalized adults显示文摘 | Bates DW Leape LL Petrycki S | 1993 | J Gen Intern Med1993，8，6： | 1 |
| 13 | The periodicity of lateralized epileptiform discharges显示文摘 | Gross DW Wiebe S Blume WT | 1999 | Clin Neurophysiol1999，，9： | 1 |
| 14 | GP73,a resident Golgi glycoprotein,is sensibility and specificity for hepato cellular carcinoma of diagnosis in a hepatitis B-en demic Asian population显示文摘 | Hu JS Wu DW Liang S | 2010 | Med Oncol2010，27，2： | 1 |
| 15 | Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells显示文摘 | Bollag G Clapp DW Shih S | 1996 | Nat Genet1996，12，2： | 1 |
| 16 | Iron deficiency anemia and iron losses after renal transplantation显示文摘 | Zheng S Coyne DW Joist H | 2009 | Transpl Int2009，22，4： | 1 |
| 17 | What's swot in strategic analysis显示文摘 | Pickton DW Wright S | 1998 | Strategic change1998，7，2： | 1 |
| 18 | Analysis and compensation of current measurementerror in vector-controlled AC motor drives 显示文摘 | CHUNG DW SUL S K | 1998 | IEEE Transactionon Industry Applications1998，34，34： | 1 |
| 19 | Interocular comparison of nerve fiber layer thickness and itsrelation with optic disc size in nor- mal subjects 显示文摘 | Ha DW Sung K Kim S | 2002 | Korean J Ophthalmol2002，16，1： | 1 |
| 20 | Controversies in low pain : the surgical approach 显示文摘 | Humley EN Spengler DW Wesel S | 1994 | Instr Course Lect1994，43，： | 1 |
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