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| 1 | Through-needle all-optical ultrasound imaging in vivo: a preclinical swine study显示文摘High-frequency ultrasound imaging can provide exquisite visualizations of tissue to guide minimally invasive procedures.Here,we demonstrate that an all-optical ultrasound transducer,through which light guided by optical fibers is used to generate and receive ultrasound,is suitable for real-time invasive medical imaging in vivo.Broad-bandwidth ultrasound generation was achieved through the photoacoustic excitation of a multiwalled carbon nanotube-polydimethylsiloxane composite coating on the distal end of a 300-μm multi-mode optical fiber by a pulsed laser.The interrogation of a high-finesse Fabry–Pérot cavity on a single-mode optical fiber by a wavelength-tunable continuous-wave laser was applied for ultrasound reception.This transducer was integrated within a custom inner transseptal needle(diameter 1.08 mm;length 78 cm)that included a metallic septum to acoustically isolate the two optical fibers.The use of this needle within the beating heart of a pig provided unprecedented realtime views(50 Hz scan rate)of cardiac tissue(depth:2.5 cm;axial resolution:64μm)and revealed the critical anatomical structures required to safely perform a transseptal crossing:the right and left atrial walls,the right atrial appendage,and the limbus fossae ovalis.This new paradigm will allow ultrasound imaging to be integrated into a broad range of minimally invasive devices in different clinical contexts. | Malcolm C Finlay Charles A Mosse Richard J Colchester Sacha Noimark Edward Z Zhang Sebastien Ourselin Paul C Beard Richard J Schilling Ivan P Parkin Ioannis Papakonstantinou Adrien E Desjardins | 2017 | Light(Science & Applications)2017，6，1： | 6 |
| 2 | A test of climate, sun, and culture relationships from an 1 810 year Chinese ca- ve record显示文摘 | Zhang P Z Cheng H Edwards R L | 2008 | Science2008，322，： | 1 |
| 3 | Treatment of naphthalene-2-sulfonic acid from tannery wastewater by a granular activatedcarbon fixed bed inoculated with bacterial isolates Arthrobacterglobiformis and Comamonas testosteroni显示文摘 | Song Z Edwards S R Burns R G | | 0，，03： | 1 |
| 4 | A test of climate, sun,and culture relationships from an 1810-year Chinese cave record显示文摘 | Zhang P Z Cheng H Edwards R L | 2008 | Science2008，322，： | 1 |
| 5 | Carbon dynamics in a temperate grassland soil after 9 years exposure to elevated COs (Swiss FACE)显示文摘 | Xie Z Cadiseh G Edwards G | 2005 | Soil Biology and Biochemistry2005，37，： | 1 |
| 6 | Increased superoxide pro-duction in coronary arteries in hyperhomocysteinemia : role of tumornecrosis factor-alpha, NADPH oxidase, and inducible nitric oxidesynthase 显示文摘 | Ungvari Z Csiszar A Edwards JG | 2003 | Arterioscler Thromb Vase Biol2003，23，3： | 1 |
| 7 | Structural Characterization of the Released Polysaccharide of Desiccation-Tolerant Nostoc commune DRH-1 显示文摘 | Helm R F Huang Z B Edwards D | 2000 | J Bact2000，182，4： | 1 |
| 8 | Neurotrophin-3 deficient Schwann cells impair nerve regeneration 显示文摘 | Sahenk Z Oblinger J Edwards C | 2008 | Exp Neurol2008，212，7： | 1 |
| 9 | Reducing Ambigui- ty in Tagging Systems with Folksonomy Search Expansion 显示文摘 | Jeff Z Pan Stuart Taylor Edward Thomas | 2009 | The Semantic Web: Research and Applications Lecture Notes in Computer Science Volume 55542009，，： | 1 |
| 10 | Interactions between nonionic surfactant monomers, hydrophobic organic compounds and soil 显示文摘 | Edwards D A Liu Z Luthy R G | 1992 | Water Air Soil Pollut1992，26，： | 1 |
| 11 | Two cytosolic glutamine synthetase isoforms of maize are specifically involved in the control of grain production 显示文摘 | Martin A Lee J Kichey T Gerentes D Zivy M Tatout C Dubois F Balliau T Valot B Davanture M Laforgue T T Quillere I Coque M Gallais A Moro M B G Bethencourt L Habash D Z Lea P J Charcosset A Perez P Murigneux A Sakakibara H Edwards K J Hirel B | 2006 | The Plant Cell2006，18，11： | 1 |
| 12 | A test of climate,sun and culture relationships from an 1810-year Chinese cave record显示文摘 | Zhang P Z Cheng H Edwards R L | | 0，，： | 1 |
| 13 | Hyperthermia,teratogenesis and the heat shock response in mammalian embryos in culture显示文摘 | Edwards MJ Walsh DA Li Z | 1997 | Int J Dev Boil1997，41，2： | 1 |
| 14 | Characterization of a North American orf virus isolated from a goat with persistent, proliferative dermatitis显示文摘 | GUO J ZHANG Z EDWARDS J F | 2003 | Virus Res2003，93，2： | 1 |
| 15 | 1990, Photosynthetic characteristics of cassava(Manihot esculenta), a C3 species with ehlorenchymatous bundle sheath cell 显示文摘 | Edwards G E Sheta E Moore B D Dai Z Franceschi V R Cheng S H Lin C H Ku M S B | 1990 | Plant and Cell Physiology1990，31，8： | 1 |
| 16 | A high- resolution, absolute-dated Holocene and deglacial Asian monsoon record from Dongge Cave, China显示文摘 | DYKOSKI C A EDWARDS R L CHENG H YUAN D X CAI Y J ZHANG M L LIN Y S QIN J M AN Z S REVENAUGH J | 2005 | Earth & Planetary Science Letters2005，233，12： | 1 |
| 17 | Structural characterization of the released polysaccharide of desiccation-tolerant Nostoc commune DRH- 1 显示文摘 | Helm R F Huang Z Edwards D | 2000 | J Bacteriol12000，182，： | 1 |
| 18 | Treatment of naphthalene-2- sulfonie acid from tannery wastewater by a granular activated carbon fixed bed inoculated with bacterial isolates Arthrobacter globiformis and Comamonas testosterone显示文摘 | Song Z Edwards S R Burn R G | 2006 | Water Research2006，40，3： | 1 |
| 19 | Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function显示文摘 | Csiszar A Ungvari Z Edwards JG | | 0，，11： | 1 |
| 20 | Solubilization of pulycyclic aromatic hydrocarbons in micellar nonionic surfaetant solutions显示文摘 | EDWARDS D A LUTHY R G LIU Z | 1991 | Environ Sci Technol1991，25，1： | 1 |
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