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| 1 | Should dopamine be the first line inotrope in the treatment of neonatal hypotension? Review of the evidence显示文摘AIM: To determine if dopamine is effective in treating neonatal hypotension and safe to use comparing to other inotropes. METHODS: This is a review of evidence on inotropic treatment of neonatal hypotension. Databases searched were MEDLINE and the Cochrane Library, a total of 134 studies were identified. Only studies with high quality evidence(level 1a and b and 2a) were included. After review, only eight studies were included in the final analysis. Pooled risk ratios derived for each outcome [Mantel-Haenzel(M-H) fixed effect] with CI, as reported in the Cochrane reviews were plotted in forest plot form. RESULTS: Eight articles met inclusion criteria, which all included treatment in preterm infants. Dopamine increased mean arterial blood pressure(BP)(n = 163; r = 0.88, 95%CI: 0.76 to 0.94) and systolic BP(n = 142; r = 0.81, 95%CI: 0.42 to 0.94) comparing to placebo. Dopamine has been shown overall to be statistically more effective in increasing BP than dobutamine(n = 251, r = 0.26, 95%CI: 0.20-0.32). However there were no differences in short term outcomes(periventricular leucomalacia, periventricular haemorrhage) and mortality between both drugs. There is no statistical evidence of dopamine being more effective than adrenaline or corticosteroids. There was no difference in morbidity and mortality outcomes when dopamine was compared to hydrocortisone(RR 1.81, 95%CI: 0.18 to 18.39) or adrenaline. CONCLUSION: In preterms, dopamine is the most studied drug, and we suggest it could be used as first line treatment in hypotension. | Sadaf I Bhayat Harsha MS Gowda Michael Eisenhut | 2016 | World Journal of Clinical Pediatrics2016，5，2： | 3 |
| 2 | NeoGemOx: Gemcitabine and oxaliplatin as neoadjuvant treatment for locally advanced, nonmetastasized pancreatic cancer显示文摘 | Klaus Sahora Irene Kuehrer Axel Eisenhut Belgin Akan Claus Koellblinger Peter Goetzinger Bela Teleky Raimund Jakesz Markus Peck-Radosavljevic Ahmed Ba’ssalamah Christoph Zielinski Michael Gnant | 2011 | Surgery2011，，3： | 2 |
| 3 | Comparison of PET/CT and PET/MRI hybrid systems using a 68 Ga-labelled PSMA ligand for the diagnosis of recurrent prostate cancer: initial experience显示文摘 | A. Afshar-Oromieh U. Haberkorn H. P. Schlemmer M. Fenchel M. Eder M. Eisenhut B. A. Hadaschik A. Kopp-Schneider M. R?thke | 2014 | European Journal of Nuclear Medicine and Molecular Imaging2014，，5： | 2 |
| 4 | Comparison of PET imaging with a 68 Ga-labelled PSMA ligand and 18 F-choline-based PET/CT for the diagnosis of recurrent prostate cancer显示文摘 | Ali Afshar-Oromieh Christian M. Zechmann Anna Malcher Matthias Eder Michael Eisenhut Heinz G. Linhart Tim Holland-Letz Boris A. Hadaschik Frederik L. Giesel Jürgen Debus Uwe Haberkorn | 2014 | European Journal of Nuclear Medicine and Molecular Imaging2014，，1： | 2 |
| 5 | PET imaging with a [ 68 Ga]gallium-labelled PSMA ligand for the diagnosis of prostate cancer: biodistribution in humans and first evaluation of tumour lesions显示文摘 | A. Afshar-Oromieh A. Malcher M. Eder M. Eisenhut H. G. Linhart B. A. Hadaschik T. Holland-Letz F. L. Giesel C. Kratochwil S. Haufe U. Haberkorn C. M. Zechmann | 2013 | European Journal of Nuclear Medicine and Molecular Imaging2013，，4： | 2 |
| 6 | Radiolabeled peptides and proteins in cancer therapy 显示文摘 | Wang|er C Buchmann I Eisenhut M | 2007 | Protein Pept Lett2007，14，3： | 1 |
| 7 | Artemisi- nin derivatives versus quinine in treating se- vere malaria in children: a systematic review 显示文摘 | Praygod G Frey A Eisenhut M | 2008 | MalarJ2008，7，： | 1 |
| 8 | SF-FLT: portrait of a prolifer- ation marker显示文摘 | Mier W Haherkorn U Eisenhut M | 2002 | Eur J Nucl Med Mol Imaging2002，29，： | 1 |
| 9 | Significance of reduced reactivity in ELISPOT assay to RD antigens of Mycobacterium tuberculosis in BCG vaccinated individuals exposed to a patient with tuberculosis显示文摘 | Eisenhut M | 2010 | Virulence2010，1，2： | 1 |
| 10 | Antiviral effects of glycyrrhiza species显示文摘 | Fiore C Eisenhut M Krausse R | 2008 | Phytother Res2008，22，2： | 1 |
| 11 | Right ventricular func- tion in children with severe respiratory syncytial virus (RSV) bronchiolitis显示文摘 | Thorburn K Eisenhut M Shauq A | 2011 | Minerva Anestesiol2011，77，1： | 1 |
| 12 | Transaminase levels in ventilated children with respiratory syneytial virus bronchiolitis显示文摘 | Eisenhut M Thorburn K Ahmed | 2004 | Intensive Care Med2004，30，5： | 1 |
| 13 | Transaminase levels in ventilated children with respiratory syncytial virus bronchiolitis显示文摘 | Eisenhut M Thorburn K Ahmed T | 2004 | Intensive Care Med2004，30，5： | 1 |
| 14 | Functional genomics and proteomicsthe role of nuclear medicine显示文摘 | Haberkorn U Altmann A Eisenhut M | 2002 | Eur J Nucl Med2002，29，1： | 1 |
| 15 | Determination of boron isotopic variations in aquatic systems with vegative thermal ionization mass spectrometry as a tracer for anthropogenic influences显示文摘 | EISENHUT S HEUMANN K G VENGOSH A | 1996 | Fresenius J Anal Chem1996，354，： | 1 |
| 16 | Mediators of cellular stress response in bacterial meningitis 显示文摘 | Eisenhut M | 2008 | Critical Care Medicine2008，36，1： | 1 |
| 17 | FLT: portrait of a proliferation marker显示文摘 | Mier W Haberkorn U Eisenhut M | 2002 | Eur J Nucl Med2002，29，2： | 1 |
| 18 | Cerebrospinal Fluid Glucose Levelsand Sensorineural Hearing Loss in BacterialMeningitis显示文摘 | M. Eisenhut T. Meehan L. Batchelor | 2003 | Infection2003，，4： | 1 |
| 19 | Comparison of the diag nostic value of MR imaging and ophthalmoscopy for the staging of retinoblastoma显示文摘 | Khurana A Eisenhut CA Wan W | 2013 | Eur Radiol2013，23，5： | 1 |
| 20 | 指南结核病的诊断、治疗及防控:最新NICE指南概要显示文摘与其他西欧国家相比,英国的结核病疫情仍较严峻。结核病最易发生在得不到充分社会保障的群体,如流浪汉、居住条件差的或贫困人群、吸毒人群及来自于结核病高发国家的人群。然而很多病例是可以通过公共卫生措施进行预防的。 | Lucy Elizabeth Hoppe Rachel Kettle Michael Eisenhut Ibrahim Abubakar 闫丽萍 沙巍 | 2016 | 英国医学杂志中文版2016，0，6： | 1 |
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