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| 1 | Optimization of biliary drainage in inoperable distal malignant strictures显示文摘BACKGROUND Given most patients with distal malignant biliary obstruction present in the nonresectable stage,palliative endoscopic biliary drainage with fully covered metal stent(FCMS)or uncovered metal stent(UCMS)is the only available measure to improve patients’quality of life.Half covered metal stent(HCMS)has been recently introduced commercially.The adverse effects and stent function between FCMS and UCMS have been extensively discussed.AIM To study the duration of stent patency of HCMS and compare it with FCMS and UCMS to optimize biliary drainage in inoperable patients with distal malignant obstruction.Secondary aims in our study included evaluation of patients’survival and the rates of adverse events for each type of stent.METHODS We studied 210 patients and randomized them into three equal groups;HCMS,FCMS and UCMS were inserted endoscopically.RESULTS Stent occlusion occurred in(18.6%,17.1%and 15.7%in HCMS,FCMS and UCMS groups,respectively,P=0.9).Stent migration occurred only in patients with FCMS(8.6%of patients).Cholangitis and cholecystitis occurred in 11.4%and 5.7%of patients,respectively,in FCMS.Tumor growth occurred only in 10 cases among patients with UCMS after a median of 140 d,sludge occurred in nine,seven and one patients in HCMS,FCMS and UCMS,respectively(P=0.04).CONCLUSION Given the prolonged stent functioning time,the use of HCMS is preferred over the use of UCMS and FCMS for optimizing biliary drainage in patients with distal malignant biliary obstruction. | Esam Elshimi Wesam Morad Omar Elshaarawy Ahmed Attia | 2020 | World Journal of Gastrointestinal Endoscopy2020，12，9： | 5 |
| 2 | Bile acids induce overexpression of ho-meobox gene CDX-2 and vascular endothelial growth factor (VEGF) in hu-man Barrett , s esophageal mucosa and adenocarcinoma cell line 显示文摘 | Burnat G Rau T Elshimi E | 2007 | Scand J Gastroenterol2007，42，12： | 1 |
| 3 | Non-line-sight single-scatter propagation model for noneoplanar geometries显示文摘 | ELSHIMY MOHAMED A HRANILOVIC | 2011 | Journal of the Optic Society of America A2011，28，3： | 1 |
| 4 | Non line of sight single scatter propagation model for noncoplanar geometries 显示文摘 | MOHAMED A Elshimy STEVE Hranilovic | 2011 | Optical Society of America2011，28，3： | 1 |
| 5 | Mannose-bingding lectin deficiency in preterm neonates显示文摘 | Elshimi MS Khafagy SM Abdel-al H | 2010 | Egypt J Pediatr Allergy Immunol2010，8，2： | 1 |
| 6 | Non-line-of-sight single- scatter propagation model for noneoplanar geometries 显示文摘 | ELSHIMY M A HRANILOVIC S | 2011 | Optical Society of America2011，28，3： | 1 |
| 7 | Impact of Finite Receiver-Aperture Size in a Non-Line-of Sight Single- Scatter Propagation Model 显示文摘 | ELSHIMY MOHAMEDA HRANILOVIC STEVE | 2011 | Journal of the Optical Society of America: Optics and Image Science and Vision2011，28，12： | 1 |
| 8 | Impact of finite receiver-aperture size in a non-line-of-sight single scatter propagation model显示文摘 | M A Elshimy S Hranilovie | 2011 | J OptSoeAmA2011，28，12： | 1 |
| 9 | Non-line of sight single-scatter propagation model for noneoplanar geometries显示文摘 | Mohamed A Elshimy Steve Hranilovie | 2011 | J Opt Soc Am A2011，28，3： | 1 |
| 10 | Progressive spinal cord compression due to epidural extramedullary hematopoiesis in thalassemia intermedia, a case report and literature review显示文摘 | Ghieda U Elshimy M E1 Beltagi A H | 2013 | Neuroradiol J2013，26，1： | 1 |
| 11 | Non line of sight single scatter propagation model for noncoplanar geometries 显示文摘 | Mohamed A Elshimy Steve Hranilovic | 2011 | Optical Society of America2011，28，3： | 1 |
| 12 | Outcomes of curative liver resection for hepatocellular carcinoma in patients with cirrhosis显示文摘BACKGROUND Given the poor synthetic function of cirrhotic liver,successful resection for patients with hepatocellular carcinoma(HCC)necessitates the ability to achieve resections with tumor free margins.AIM To validate post hepatectomy liver failure score(PHLF),compare it to other established systems and to stratify risks in patients with cirrhosis who underwent curative liver resection for HCC.METHODS Between December 2010 and January 2017,120 patients underwent curative resection for HCC in patients with cirrhosis were included,the pre-operative,operative and post-operative factors were recorded to stratify patients'risks of decompensation,survival,and PHLF.RESULTS The preoperative model for end-stage liver disease(MELD)score[odds ratio(OR)=2.7,95%CI:1.2-5.7,P=0.013],tumor diameter(OR=5.4,95%CI:2-14.8,P=0.001)and duration of hospital stay(OR=2.5,95%CI:1.5-4.2,P=0.001)were significant independent predictors of hepatic decompensation after resection.While the preoperative MELD score[hazard ratio(HR)=1.37,95%CI:1.16-1.62,P<0.001]and different grades of PHLF(grade A:HR=2.33,95%CI:0.59-9.24;Grade B:HR=3.15,95%CI:1.11-8.95;Grade C:HR=373.41,95%CI:66.23-2105.43;P<0.001)and HCC recurrence(HR=11.67,95%CI:4.19-32.52,P<0.001)were significant independent predictors for survival.CONCLUSION Preoperative MELD score and tumor diameter can independently predict hepatic decompensation.While,preoperative MELD score,different grades of PHLF and HCC recurrence can precisely predict survival. | Omar Elshaarawy Aya Aman Hazem Mohamed Zakaria Talaat Zakareya Asmaa Gomaa Esam Elshimi Eman Abdelsameea | 2021 | World Journal of Gastrointestinal Oncology2021，13，5： | 0 |
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