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20篇 您的检索式:作者名="ERION D M"
    题名 作者 年代 出处 被引量
1The hepatoselectiveglucokinase activator PF-04991532 ameliorates hyperglycemia without causing hepatic steatosis in diabetic rats 显示文摘Erion D M Lapworth A Amor P A 2014PLoS One2014,9,97:1
2Discovery of fructose-1,6-bisphosphatase inhibitors for the treatment of type 2 diabetes显示文摘VANPOELJE P D DANG Q ERION M D 2007Curr Opin Drug Discov Devel2007,10,4:1
3Hypoglycaenfic effect of AICAriboside in mice显示文摘Vincent M F Erion M D ( ruber H E el al 1996Diabetolog4a1996,39,10:1
4The role of peroxisome proliferator-activated receptorγ coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance 显示文摘Nagai Y Yonemitsu S Erion D M 2009Cell Metab2009,9,3:1
5Fructose-1, 6-bi- sphosphatase as a therapeutic target for type 2 diabetes 显示文摘VAN POELJE P D DANG Q ERION M D 2007Drug Discov Today2007,4,2:1
6Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease显示文摘KUMASHIRO N ERION D M ZHANG D 2011PNAS2011,108,16:1
7Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease显示文摘Kumashiro N Erion D M Zhang D 2011Proceedings of the National Academy of Sciences2011,108,16:1
8The role of peroxisome proliferator-activated receptor gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance显示文摘Nagai Y Yonemitsu S Erion D M 2009Cell Metab2009,9,3:1
9SIRT1 regulates adipose tissue inflammation 显示文摘GILLUM M P KOTAS M E ERION D M 2010Dia-betes2010,60,12:1
10Liver-targeted drug delivery using HepDirect prodrugs显示文摘Erion M D van Poelje P D Mackenna D A et a1 2005J Pharmacol Exp Ther2005,312,2:1
11The role of peroxisome proliferator-activated receptoR gamma coactivator-1 beta in the pathogenesis of fructose-induced insulin resistance显示文摘Nagai Y Yonemitsu S Erion D M 2009Cell Metab2009,9,3:1
12Prodrugs of phosphates and phosphonates显示文摘Hecker S J Erion M D 2008J Med Chem2008,51,8:1
13Structure- guided design of AMP mimics that inhibit fructose-I, 6-bisphosphatase with high affinity and specificity显示文摘Erion M D Dang Q Reddy M R 2007Journal of the American Chemical Society2007,129,15:1
14Sirtl knockdown in liver decreases basal hepatic glucose production and increases hepatic insulin responsiveness in diabetic rats显示文摘ERION D M YONEMITSU S NIE Y 2009Proc Natl Acad Sci USA2009,106,11:1
15Liver-targeted drug delivery using HepDirect prodrugs显示文摘Erion M D van Poelje P D Mackenna D A 2005J Pharmacol Exp Ther2005,312,2:1
16Sirtl knockdown in liver decreases basal hepatic glucose production and increases he- patic insulin responsiveness in diabetic rats显示文摘ERION D M YONEMISTSU S NIE Y 2009Proc Natl Acad Sci USA2009,106,11:1
17Prodrugs of phosphates and phosphonates显示文摘Hecker S J Erion M D 2008J Med Chem2008,51,:1
18Prevention of hepatic steatosis and hepatic in- sulin resistance by knockdown of cAMP response element-binding protein 显示文摘Erion D M Ignatova I D Yonemitsu S 2009Cell Metab2009,10,:1
19Design, synthesis, and characterization of a series of cytochrome P450 3A-activated prodrugs (HepDirect prodrugs) useful for targeting phosph(on)ate-based drugs to the liver显示文摘Erion M D Reddy K R Boyer S H 2004J Am Chem Soc2004,126,:1
20L iver-targeted drug delivery us ing hepDirect prodrugs显示文摘Erion M D Van Poelje Mackenna D A 2005J Pharm Exp Ther2005,312,2:1
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