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| 1 | Photodynamic therapy vs radiofrequency ablation for Barrett's dysplasia: Efficacy,safety and cost-comparison显示文摘AIM:To compare effectiveness,safety,and cost of photodynamic therapy(PDT)and radiofrequency ablation(RFA)in treatment of Barrett’s dysplasia(BD).METHODS:Consecutive case series of patients undergoing either PDT or RFA treatment at single center by a single investigator were compared.Thirty-three patients with high-grade dysplasia(HGD)had treatment with porfimer sodium photosensitzer and 630 nm laser(130 J/cm),with maximum of 3 treatment sessions.Fifty-three patients with BD(47 with low-grade dysplasia-LGD,6 with HGD)had step-wise circumferential and focal ablation using the HALO system with maximum of 4 treatment sessions.Both groups received proton pump inhibitors twice daily.Endoscopic biopsies were acquired at 2 and 12 mo after enrollment,with 4-quadrant biopsies every 1 cm of the original BE extent.A complete histological resolution response of BD(CR-D)was defined as all biopsies at the last endoscopy session negative for BD.Fisher’s exact test was used to assess differences between the two study groups for primary outcomes.For all outcomes,a two-sided P value of less than 0.05 was considered to indicate statistical significance.RESULTS:Thirty(91%)PDT patients and 39(74%)RFA were men(P=0.05).The mean age was 70.7±12.2 and 65.4±12.7(P=0.10)year and mean length of BE was 5.4±3.2 cm and 5.7±3.2 cm(P=0.53)for PDT and RFA patients,respectively.The CR-D was(18/33)54.5%with PDT vs(47/53)88.7%with RFA(P=0.001).One patient with PDT had an esophageal perforation and was managed with non-surgical measures and no perforation was seen with RFA.PDT was five times more costly than RFA at our institution.The two groups were not randomized and had different BD grading are the limitations of the study.CONCLUSION:In our experience,RFA had higher rate of CR-D without any serious adverse events and was less costly than PDT for endoscopic treatment of BD. | Atilla Ertan Irum Zaheer Arlene M Correa Nirav Thosani Shanda H Blackmon | 2013 | World Journal of Gastroenterology2013,19,41: | 7 |
| 2 | 老年男性勃起功能及迟发性性腺功能减退症状与下尿路症状严重性的关系显示文摘本文旨在研究土耳其爱琴海地区的老年男性下尿路症状(LUTSs)、勃起功能障碍(ED)和有症状的迟发性性腺功能减退症(SLOH)三者间的关系。符合以下标准的500名男性患者被纳入该研究:40周岁以上;过去6个月内有稳定的性关系;在六个泌尿外科诊所之一进行过就诊登记。每位患者均行血清PSA、睾酮水平及尿流率的检测,并填写国际前列腺症状评分和生活质量评分(IPSS-QoL)量表、国际勃起功能指数(IIEF)问卷和老年男性症状(AMS)量表。在所有的研究对象中,23.9%的患者有轻度LUTSs,53.3%有中度LUTSS,22.8%有重度LUTSS。每组间总睾酮水平无明显差异。除此之外,69.6%的病人患有ED,且ED的发生率与LUTS严重性呈正相关。71.2%的患者出现SLOH(AMS〉27),且IPSS评分越高,严重的性腺功能减退症状的发生率也越高。相关性分析显示以上三种问卷分数之间有显著关联。总之,LUTS严重性是ED和SLOH的非年龄依赖性危险因素,LUTS严重性和SLOH症状之间似乎有显著的相关性,但还需要从病因学和生物学角度进行深入阐明。 | Ozan Bozkurt Deniz Bolat Omer Demir Oktay Ucer Ali Sahin Burak Ozcift Abdulkadir Pekta Tahir Turan Bilal H Gümü Ertan Cans Ahmet Bolukbasi Haluk Erol Adil Esenx | 2013 | Asian Journal of Andrology2013,15,6: | 4 |
| 3 | Atonomous wind energy conversion system with a simple controller for maximum-power transfer 显示文摘 | Ermis A Ertan M Akpinar H B | 1992 | Electric Power Applications IEE Proceedings B1992,139,5: | 2 |
| 4 | An Analysis of Spatial and Temporal Dimension of Drought Vulnerability in Turkey Using the Standardized Precipitation Index显示文摘 | F. KEMAL. S?NMEZ ALI üMRAN K?MüSCü AYHAN ERKAN ERTAN TURGU | 2005 | Natural Hazards2005,,2: | 2 |
| 5 | A prospective randomized trial comparing the harmonic scalpel with conventional knot tying in thyrnidectomy 显示文摘 | Kilic M Keskek M Ertan T | 2007 | Adv Ther2007,24,3: | 1 |
| 6 | Second de- rivative spectrophotometric determination o{ p-amino- phenol in the presence of paracetamol 显示文摘 | YESILADA A ERDOGAN H ERTAN M | 1991 | Analy Lett1991,24,1: | 1 |
| 7 | Randomized,prospective comparison of postoperative pain in low-versus high-pressure pneumoperitoneum显示文摘 | Koc M Ertan T Tez M | 2005 | ANZ J Surg2005,75,8: | 1 |
| 8 | Chiral capillary electrophoresis:Facts and fiction on the re- producibility of resolution with randomly substituted cyclodextrins 显示文摘 | SCHMITT U ERTAN M HOLZGRABE U | 2004 | Electrophoresis2004,25,16: | 1 |
| 9 | In vitro aldose reductase inhibitory activity of some flavonyl-2,4-thiazolidinediones显示文摘 | Das-Evcimen N Sarikaya M Ertan R | 2008 | Enzyme Inhib Med Chem2008,23,3: | 1 |
| 10 | Fas ligand expression in esophageal carcinomas and their lymph node metastases 显示文摘 | Younes M Schwartz MR Ertan A | 2000 | Cancer2000,88,3: | 1 |
| 11 | A prospective randomized trial comparing the harmonic scalpel with conventional knot tying in thyroidectomy 显示文摘 | Kilic M Keskek M Ertan T | 2007 | Adv Ther2007,24,3: | 1 |
| 12 | Synthesis, structural elucidation and pharmacological properties of some 5-acetyl-3, 4-dihydro-6-methyl-4-(substituted phenyl)-2 (1 H)-pyrimidinones 显示文摘 | Sara? S Ertan M | 1999 | IL Farmaco1999,54,: | 1 |
| 13 | Chiral capillary electrophoresis:facts and fiction on the reproducibility of resolution with randomly substituted cyclodextrins显示文摘 | Schmitt U Ertan M Holzgrabe U | 2004 | Electrophoresis2004,,25: | 1 |
| 14 | Randomized,prospective comparison of postoperative pain in low-versus high-pressure pneumoperitoneum显示文摘 | Ertan T Tez M | 2005 | Anz J Surg2005,75,8: | 1 |
| 15 | Relationship of sleep quality and quality of life in children with monosymptomatic enuresis 显示文摘 | Ertan P Yilmaz O Caglayan M | 2009 | Child Care Health Dev2009,35,4: | 1 |
| 16 | Effect of casting parameters on twin roll casting strip显示文摘 | Ertan S Dundar M Birol Y | 2000 | Light Metals2000,,: | 1 |
| 17 | Perception of pain during orthodontic treatment with fixed appliances 显示文摘 | Aslihan M Ertan Erdinc and Banu Dincer | 2004 | Eur J Orthod2004,26,: | 1 |
| 18 | Fas ligand expression in esophageal carcinomas and their lymph node metastases 显示文摘 | Younes M Schwartz MR Ertan A | 2000 | Cancer2000,88,3: | 1 |
| 19 | The effect of casting parameters on twin roll casting strip显示文摘 | ERTAN S DUNDAR M BIROL Y | 2000 | Light Metals2000,,: | 1 |
| 20 | A prospective randomized trial comparing the harmonic scalpel with conventional knot tying in thyroidectomy显示文摘 | Kilic M Keskek M Ertan T | | 0,,03: | 1 |